[1]王光,陈晓隆,王爱媛,等.糖尿病视网膜病变患者全视网膜激光光凝前后视网膜动、静脉循环时间的改变[J].眼科新进展,2017,37(10):962-965.[doi:10.13389/j.cnki.rao.2017.0244]
　WANG Guang,CHEN Xiao-Long,WANG Ai-Yuan,et al.Changes of retinal circulation time before and after panretinal laser photocoagulation in patients with diabetic retinopathy[J].Recent Advances in Ophthalmology,2017,37(10):962-965.[doi:10.13389/j.cnki.rao.2017.0244]
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糖尿病视网膜病变患者全视网膜激光光凝前后视网膜动、静脉循环时间的改变/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年10期
页码:
962-965
栏目:
应用研究
出版日期:
2017-10-05

文章信息/Info

Title:
Changes of retinal circulation time before and after panretinal laser photocoagulation in patients with diabetic retinopathy
作者:
王光; 陈晓隆; 王爱媛; 赵芳; 施丰雪; 翟文佳; 王晶雪
110001　辽宁省沈阳市，中国医科大学附属盛京医院眼科
Author(s):
WANG Guang; CHEN Xiao-Long; WANG Ai-Yuan; ZHAO Fang; SHI Feng-Xue; ZHAI Wen-Jia; WANG Jing-Xue
Department of Ophthalmology，Shengjing Hospital of China Medical University，Shenyang 110001，Liaoning Province，China
关键词:
糖尿病视网膜病变; 全视网膜激光光凝; 视网膜循环时间; 荧光素眼底血管造影
Keywords:
diabetic retinopathy; panretinal laser photocoagulation; retinal circulation time; fundus fluorescein angiography
分类号:
R774.1
DOI:
10.13389/j.cnki.rao.2017.0244
文献标志码:
A
摘要:
目的　观察糖尿病视网膜病变（diabetic retinopathy，DR）患者全视网膜激光光凝（pan-retinal laser photocoagulation，PRP）治疗前后视网膜动、静脉循环时间的改变。方法　经荧光素眼底血管造影（fundus fluorescein angiography，FFA）检查确诊为重度非增殖期及增殖期DR且符合PRP适应证的16例（16眼）患者纳入研究，并行PRP。治疗前、治疗后1~3个月，采用FFA对所有患眼视网膜动、静脉循环时间进行记录，观察视网膜动脉4个分支主干出现显影的时间、完全充盈的时间，视网膜静脉4个分支主干全部出现层流的时间、完全充盈的时间，计算得出视网膜动脉、视网膜毛细血管、视网膜静脉、视网膜动静脉通过时间，对比观察治疗前后患眼不同时段的视网膜通过时间的变化。结果　DR患者PRP治疗前视网膜毛细血管通过时间为（1.58±0.99）s，治疗后为（2.19±1.23）s，差异有统计学意义（P=0.011）。DR患者PRP治疗前后的视网膜动脉、视网膜静脉、视网膜动静脉通过时间的差异均无统计学意义（均为P＞0.05）。结论　PRP是DR患者的最重要治疗方式，在PRP治疗后1~3个月视网膜毛细血管通过时间的血流动力学改变最为显著，较PRP治疗前有显著延长。
Abstract:
Objective　To observe the changes of preoperative and postoperative retinal circulation time in panretinal laser photocoagulation (PRP) in patients with diabetic retinopathy (DR).Methods　Together 16 patients (16 eyes) were collected as the subjects in this study，who was diagnosed as severe non-proliferative and proliferative DR by fundus fluorescein angiography (FFA) examination and had PRP indications for undergoing pan-retinal laser photocoagulation.Then retinal arterial and venous circulation time in all patients was recorded using FFA before and 1 to 3 months after treatment.Meanwhile，it was necessary to observe the following variables，including the developing duration and complete filling time of the four branches of the retinal artery，as well as the duration of the laminar flow and complete filling time of the four branches of the venous artery，followed by calculating mean transition time of retinal artery，retinal capillary，retinal vein，retinal arteriovenous flow for comparison and analysis of changes in transit time of retina in different time-periods before and after treatment.Results　The mean transition time of the retinal capillary in patient was (1.58±0.99)s before treatment and (2.19±1.23)s after treatment，and the difference was statistically significant（P=0.011)，but there was no significant difference in the mean transition time of the retinal artery，retinal vein and arteriovenous flow (all P>0.05).Conclusion　The transit time of the retinal capillary at 1 to 3 months after PRP is significantly longer than that before treatment.

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更新日期/Last Update: 2017-10-24