[1]詹冬梅,史琴,哈玲芳,等. 两种联合术式人工晶状体植入术治疗增生性糖尿病视网膜病变的对比研究[J].眼科新进展,2015,35(3):266-269.[doi:10.13389/j.cnki.rao.2015.0071]
　ZHAN Dong-Mei,SHI Qin,HA Ling-Fang,et al. Comparative study of vitrectomy combined with phacoemulsification or pars plana lensectomy for proliferative diabetic retinopathy[J].Recent Advances in Ophthalmology,2015,35(3):266-269.[doi:10.13389/j.cnki.rao.2015.0071]
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 两种联合术式人工晶状体植入术治疗增生性糖尿病视网膜病变的对比研究
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年3期
页码:
266-269
栏目:
应用研究
出版日期:
2015-03-05

文章信息/Info

Title:
 Comparative study of vitrectomy combined with phacoemulsification or pars plana lensectomy for proliferative diabetic retinopathy
作者:
 詹冬梅; 史琴; 哈玲芳; 武淑玲
 750004　宁夏回族自治区银川市，宁夏医科大学总医院眼科
Author(s):
 ZHAN Dong-Mei ;  SHI Qin ;  HA Ling-Fang ; WU Shu-Ling
 Department of Ophthatmology, the General Hospital of Ningxia Medical University , Yinchuan 750004 , Ningxia Hui Autonomous Region , China
关键词:
 ; 增生性糖尿病视网膜病变; 超声乳化术; 玻璃体切割术; 晶状体切割术; 虹膜新生血管
Keywords:
 ; proliferative diabetic retinopathy;  phacoemulsification ;  vitrectomy;  pars plana lensectomy ; iris neovascuiarization
DOI:
10.13389/j.cnki.rao.2015.0071
文献标志码:
A
摘要:
 目的　对比分析两种联合术式人工晶状体植入术治疗增生性糖尿病视网膜病变的安全性和有效性。方法　回顾性分析２０１１年３月至２０１３年１０月我院收治的增生性糖尿病视网膜病变行联合手术的患者９５例（９５眼），随机分为两组，术式１组４９眼行白内障超声乳化术联合玻璃体切割囊袋内植入后房型人工晶状体；术式２组４６眼行玻璃体手术中后路切除晶状体，保留前囊膜，前囊上睫状体沟内植入人工晶状体。观察两组患者术后视力改善及术后并发症情况。术后随访５个月～２．５ａ。结果　术式１组视力改善４０眼（８１．６３％）；术式２组视力改善２８眼（６０．８７％），两组术后视力改善眼数比较差异有统计学意义（χ２＝５．０２８，Ｐ＝０．０２５）。术式１组术后发生虹膜新生血管（ｉｒｉｓｎｅｏｖａｓｃｕｉａｒｉｚａｔｉｏｎ，ＩＮＶ）１眼；术式２组术后发生ＩＮＶ７眼，两组术后ＩＮＶ发生率差异有统计学意义（χ２＝５．３４２，Ｐ＝０．０２１）。两组患者术后视力改善不佳者多伴有明显的糖尿病黄斑水肿、硬性渗出或视网膜缺血。术后主要并发症包括：角膜水肿（术式１组１２眼，术式２组５眼）、暂时性眼压升高（术式１组４眼，术式２组５眼）、葡萄膜炎表现（术式１组１６眼，术式２组１４眼）、玻璃体积血（术式１组４眼，术式２组６眼）、视网膜脱离（两组均为２眼）、新生血管性青光眼（术式１组１眼，术式２组５眼）、后发性白内障（术式１组７眼，术式２组６眼）。结论　玻璃体切割联合晶状体手术治疗合并白内障的增生性糖尿病视网膜病变是安全有效的；术式ｌ组优于术式２组，其术后ＩＮＶ和新生血管性青光眼的发生率也较低；糖尿病黄斑病变是影响术后视力提高的主要原因。
Abstract:
 Objective To evaluate the safety and effectiveness of vitrectomy combined with phacoemulsification or pars plana lensectomy for eyes with proliferative diabetic retinopathy. Methods Retrospective analysis were performed about the clinical data of 95 cases (95 eyes) with cataract and proliferative diabetic retinopathy who were received two different combined surgery from March 2011 to October 2013 in our hospital. Two groups were divided. and 49 eyes received the techniques of vitrectomy combined with phacoemulsification as group one . intraocular lens ( IOL) was implanted into the intracapsule. Another 46 eyes were treated with vitrectomy combined with lensectomy via the pars plana as group two,the IOL was inserted on the anterior capsule. Postoperative visual acuity and surgical complications were analyzed. Results The postoperative follow-up interval ranged from 5 months t0 2. 5 years. The visual improvement were achieved in 40 eyes (81. 63% ) of group one and 28 eyes (60. 87% ) of group two , there was statistical difference (X2 = 5 . 028 .P = 0. 025 ) . The eyes with low visual acuity were associated with significant diabetic macular edema. abundant macular exudate and severe ischenua. Iris neovascuiarization appeared in I eye (2. 04% ) of group one and 7 eyes of group two ( 15. 22% ) after surgery , there was statistical difference (X2 = 5. 342 ,P = 0. 021 ) . Postoperative complications included corneal edema( 12 eyes in group I and 5 eyes in group 2) , transient intraocular pressure increase (4 eyes in group I and 5 eyes in group 2) , uveitis ( 16 eyes in group I and 14 eyes in group 2) ,vitreous hemorrhage (4 eyes in group I and 6 eyes in group 2) ,retinal detachment(2 eyes in both groups) .neovascular glaucoma ( I eye in group I and 5 eyes in group 2) ,posterior capsule opacification (7 eyes in group I and 6 eyes in group 2) . Conclusion Combined surgery in the treatment of cataract and proliferative diabetic retinopathy is safe and effective. Phacoemusification and simultaneous implantation of introcapsule lens combined with vitrectomy is more effective for the eyes with cataract and proliferative diabetic retinopathy. And the visual outcome is obviously improved in the majority of selected eyes but less iris neovascuiarization appears. Diabetic macular abnormalities is main reason which affected the improvement of visual acuity.

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备注/Memo

备注/Memo:
 宁夏自然科学基金资助（编号：ＮＺ１０１２９）
更新日期/Last Update: 2015-03-04