[1]冯竞仰,陈凤娥,马明明.高度近视黄斑裂孔性视网膜脱离术后视功能及视觉相关生存质量分析[J].眼科新进展,2018,38(8):742-745.[doi:10.13389/j.cnki.rao.2018.0174]
　FENG Jing-Yang,CHEN Feng-E,MA Ming-Ming.Visual function and visual-related quality of life after vitrectomy for macular hole retinal detachment in high myopia[J].Recent Advances in Ophthalmology,2018,38(8):742-745.[doi:10.13389/j.cnki.rao.2018.0174]
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高度近视黄斑裂孔性视网膜脱离术后视功能及视觉相关生存质量分析/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
38卷
期数:
2018年8期
页码:
742-745
栏目:
应用研究
出版日期:
2018-08-05

文章信息/Info

Title:
Visual function and visual-related quality of life after vitrectomy for macular hole retinal detachment in high myopia
作者:
冯竞仰; 陈凤娥; 马明明
200080　上海市，上海交通大学附属第一人民医院，上海市眼底病重点实验室，上海眼视觉与光医学工程技术研究中心（冯竞仰）；200080　上海市，上海交通大学附属第一人民医院（陈凤娥，马明明）
Author(s):
FENG Jing-Yang; CHEN Feng-E; MA Ming-Ming
Shanghai General Hospital，Shanghai Key Laboratory of Ocular Fundus Diseases，Shanghai Engineering Center for Visual Science and Photomedicine （FENG Jing-Yang），Shanghai 200080，China；Shanghai General Hospital（CHEN Feng-E，MA Ming-Ming），Shanghai 200080，China
关键词:
高度近视; 黄斑裂孔; 视网膜脱离; 视功能; 视觉相关生存质量
Keywords:
high myopia; macular hole; retinal detachment; vision function; visual related quality of life
分类号:
R774.1
DOI:
10.13389/j.cnki.rao.2018.0174
文献标志码:
A
摘要:
目的　评估高度近视黄斑裂孔性视网膜脱离患者术后视功能和视觉相关生存质量（visual-related quality of life，VRQoL），并分析VRQoL与视功能之间的相关性。方法　回顾性分析2012年3月至2016年5月于上海交通大学附属第一人民医院行23G玻璃体切割联合内界膜剥除及硅油填充术的高度近视黄斑裂孔性视网膜脱离患者63例（63眼）术前及术后6个月的临床资料。记录主要观察指标，包括最佳矫正视力、对比敏感度。患者填写美国国家眼科研究院开发的视功能相关生存质量量表（visual function questionnaire-25，VFQ-25）中文版。比较患者手术前后VFQ-25总得分以及各维度得分，并分析其与视功能的相关性。结果　63例患者中60眼（95.24%）视网膜复位，术后6个月术眼平均logMAR视力（0.83±0.25）较基线logMAR视力（1.76±0.43）显著提高，差异有统计学意义（P<0.05）。术后术眼对比敏感度：1.5 c·d-1为1.25±0.28，3 c·d-1为1.27±0.31，6 c·d-1为1.03±0.27，12 c·d-1为0.71±0.23，18 c·d-1为0.32±0.13。术后6个月患者VFQ-25总得分均值为（66.13±11.28）分，较术前［（50.07±14.42）分］显著提高，差异有统计学意义（P<0.05）。术后VFQ-25总得分和术眼最佳矫正视力无相关性，与双眼平均视力、术眼中空间频率（6 c·d-1、12 c·d-1）对比敏感度呈正相关。结论　高度近视黄斑裂孔性视网膜脱离患者术后视网膜复位率高，视力显著提高。术后患者VRQoL提高，并与双眼平均视力、术眼中空间频率对比敏感度相关，与术眼视力无显著相关性。
Abstract:
Objective　To assess the visual function and visual-related quality of life (VRQoL) as well as their correlation after vitrectomy for macular hole retinal detachment (MHRD) in high myopia.Methods　From March 2012 to May 2016，a retrospective case series review of 63 patients (63 eyes)，who were diagnosed as MHRD and underwent 23G vitrectomy combined with internal membrane peeling and silicone oil tamponade at Shanghai General Hospital were collected.All patients were accorded with the definition of high myopia.Before and 6 months after surgery，best corrected visual acuity (BCVA) and contrast sensitivity (CS) were recorded.The Chinese version of 25-Item National Eye Institute Visual Function Questionnaire (VFQ-25) was employed to evaluate VRQoL.The total score of VFQ-25 and scores of each scale were calculated and their correlations with BCVA and CS were evaluated.Results　The anatomical reattachment rate of 63 eyes approached to 95.24% (60 eyes).The logMAR BCVA improved from (1.76±0.43) to (0.83±0.25) at 6 months after surgery (P<0.05).The postoperative CS was 1.25±0.28 (1.5 c·d-1)，1.27±0.31 (3 c·d-1)，1.03±0.27 (6 c·d-1)，0.71±0.23 (12 c·d-1)，0.32±0.13 (18 c·d-1).The total score of VFQ-25 was (66.13±11.28) points at 6 months after surgery，significantly higher than pre-operation (P<0.05).The postoperative VFQ-25 score was positively correlated with weighted average logMAR visual acuity (WMAR) and median frequency CS (6 c·d-1，12 c·d-1)，but had no correlation with BCVA of operated eyes.Conclusion　Vitrectomy combined with internal membrane peeling and silicone oil tamponade is safe and effective in treating MHRD with high myopia.The VFQ-25 scores improve after surgery.Postoperative VRQoL is correlated with WMAR and CS rather than BCVA of affected eyes.

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备注/Memo

备注/Memo:
国家自然科学基金青年项目（编号：81500732）
更新日期/Last Update: 2018-08-09