[1]姜媛,施叶雯,李佩君,等.50岁以上中心性浆液性脉络膜视网膜病变患者的脉络膜厚度分析[J].眼科新进展,2017,37(12):1169-1173.[doi:10.13389/j.cnki.rao.2017.0295]
　JIANG Yuan,SHI Ye-Wen,LI Pei-Jun,et al.Choroidal thickness in patients with central serous chorioretinopathy over 50 years old[J].Recent Advances in Ophthalmology,2017,37(12):1169-1173.[doi:10.13389/j.cnki.rao.2017.0295]
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50岁以上中心性浆液性脉络膜视网膜病变患者的脉络膜厚度分析/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年12期
页码:
1169-1173
栏目:
应用研究
出版日期:
2017-12-05

文章信息/Info

Title:
Choroidal thickness in patients with central serous chorioretinopathy over 50 years old
作者:
姜媛; 施叶雯; 李佩君; 郑波
710004　陕西省西安市，西安市第四医院眼科（姜媛，李佩君，郑波）；710004　陕西省西安市，西安交通大学第二附属医院耳鼻喉科（施叶雯）
Author(s):
JIANG Yuan; SHI Ye-Wen; LI Pei-Jun; ZHENG Bo
Department of Ophthalmology，the Fourth Hospital of Xi’an（JIANG Yuan，LI Pei-Jun，ZHENG Bo），Xi’an 710004，Shaanxi Province，China；Department of Otorhinolaryngology，the Second Affiliated Hospital of Xi’an Jiaotong University（SHI Ye-Wen），Xi’an 710004，Shaanxi Province，China
关键词:
中心性浆液性脉络膜视网膜病变; 脉络膜厚度; 光学相干断层扫描
Keywords:
central serous chorioretinopathy; choroidal thickness; optical coherence tomography
分类号:
R773.4
DOI:
10.13389/j.cnki.rao.2017.0295
文献标志码:
A
摘要:
目的　观察50岁以上中心性浆液性脉络膜视网膜病变（central serous chorioretinopathy，CSC）患者的脉络膜厚度水平。方法　选择2016年1月至2017年1月在我院确诊为CSC的50岁以上患者25例纳入研究。其中单眼20例，双眼5例，分为CSC患眼组（30眼），CSC对侧健眼组（19眼）。选择同期年龄匹配的健康人26例（26眼）作为正常对照组。使用光学相干断层扫描加强深度成像技术进行脉络膜厚度的测量，选取中心凹下，距离中心凹鼻侧500 μm、1500 μm，颞侧500 μm、1500 μm共5个位点。结果　CSC患者年龄为（60.08±7.68）岁。CSC患眼组、CSC对侧健眼组中心凹下脉络膜厚度（subfoveal choroidal thickness，SFCT）分别为（414.17±85.88）μm、（352.89±97.22）μm，较正常对照组的（280.69±90.99）明显增厚（均为P＜0.05）。单眼CSC患者患眼SFCT为（414.17±85.88）μm，较CSC对侧健眼的（352.89±97.22）μm明显增厚（P=0.008）。其余测量位点组间差异结果相似。结论　50岁以上CSC患者脉络膜较年龄匹配正常人明显增厚，患眼SFCT多在400 μm以上，这一特征有助于对老龄合并黄斑神经上皮脱离患者的鉴别诊断。
Abstract:
Objective　To investigate the choroidal thickness （CT） in patient （>50 years old） with central serous chorioretinopathy （CSC） compared to age-matched healthy controls.Methods　Together 25 （>50 years old） patients with CSC from January 2016 to January 2017 were enrolled in these study.Of 25 patients，20 patients were affected unilaterally and 5 patients were affected bilaterally.These patients were divided into affected eye group （30 eyes） and unaffected fellow eye group （19 eyes）.Addition 26 age-matched healthy subjects were recruited as control group （26 eyes）.Enhanced depth imaging technique of optical coherence tomography （EDI-OCT） was used to measure the choriodial thickness at 5 sites，including subfovea and 500 μm，1500 μm temporal and nasal to the fovea.Results　The mean age of patients with CSC was （60.08±7.68） years.The subfoveal choroid thickness of both affected eye group and unaffected fellow eye group was significantly thicker than that of the control group ［（414.17±85.88）μm vs.（352.89±97.22）μm vs.（280.69±90.99）μm］ （both P＜0.05）.In the patients with monocular affected eyes，the subfoveal choroid thickness of the affected eyes was thicker than that of the fellow eyes ［（414.07±85.88）μm vs.（352.89±97.22）μm］ （P＜0.05）.There were significant differences in choriodal thickness at other sites in the three groups （all P<0.05）.Conclusion　The choriodal thickness in patients with CSC at over 50 years of age is significantly thicker than that in the age-matched healthy subjects，with subfoveal choroid thickness >400 μm，which is helpful for the differential diagnosis of elderly patients with macular serous retinal detachment.

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更新日期/Last Update: 2017-12-08