[1]张春巍,高效曼,李睿姝,等. 应用三维光学相干断层成像术测量正常人脉络膜厚度及其影响因素的研究[J].眼科新进展,2015,35(3):274-276.[doi:10.13389/j.cnki.rao.2015.0073]
　ZHANG Chun-Wei,GAO Xiao-Man,LI Rui-Shu,et al. Assessment of choroidal thickness in hezdthy eyes using deep range imaging optical coherence tomography[J].Recent Advances in Ophthalmology,2015,35(3):274-276.[doi:10.13389/j.cnki.rao.2015.0073]
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 应用三维光学相干断层成像术测量正常人脉络膜厚度及其影响因素的研究
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年3期
页码:
274-276
栏目:
应用研究
出版日期:
2015-03-05

文章信息/Info

Title:
 Assessment of choroidal thickness in hezdthy eyes using deep range imaging optical coherence tomography
作者:
 张春巍; 高效曼; 李睿姝; 刘玲华
 150001　黑龙江省哈尔滨市，哈尔滨医科大学附属第一医院眼科
Author(s):
 ZHANG Chun-Wei ;  GAO Xiao-Man ;  LI Rui-Shu ;  LIU Ling-Hua
 Department of Ophthalmology,the First Affiliated Hospital of Harbin Medical University, Harbin 150001,Heilongjiang Provice.China
关键词:
 ; 脉络膜厚度; 三维光学相干断层成像术; 年龄; 眼轴长度
Keywords:
 ; choroidal thickness;  deep range imaging optical coherence tomography ;  age ;  axial length
DOI:
10.13389/j.cnki.rao.2015.0073
文献标志码:
A
摘要:
 目的　应用三维光学相干断层成像术测量正常人脉络膜厚度，并分析其相关影响因素。方法　应用三维光学相干断层成像术对６７位（１０６眼）正常人进行后极部脉络膜厚度的测量，软件自动测量并获得脉络膜厚度值。采用单变量和多变量回归分析脉络膜厚度与年龄、性别、眼轴长度、收缩期眼灌注压、舒张期眼灌注压、中央角膜厚度及眼压的关系。结果　正常人眼脉络膜厚度为（１７９．９±３６．１）μｍ。脉络膜厚度随着年龄的增加和眼轴的延长而变薄，呈高度线性负相关性（均为Ｐ＜０．０５），多变量回归分析结果显示，年龄每增加１０ａ，脉络膜厚度平均下降８．６２μｍ，而眼轴长度每增加１ｍｍ，脉络膜厚度平均下降１２．７０μｍ。脉络膜厚度与性别、中央角膜厚度等因素无相关关系。结论　ＤＲＩＯＣＴ可定量检测正常人脉络膜厚度；正常人的脉络膜厚度与年龄和眼轴长度呈负相关。
Abstract:
 Objective To evaluate the choroidal thickness ( CT) and its relationship with age and axial length in healthy eyes using deep range imaging optical coherence tomography ( DRI-OCT). Methods A total of 106 eyes of 67 healthy subjects were enrolled in this study. CT was assessed by DRI-OCT. The association between CT and potential confounding variables including age , gender , axial length , intraocular pressure .central corneal thickness and ocular perfusion pressure was exanuned using univariable and multivariable regression analyses. Results Overall CT was ( 179. 9 + 36. I ) ym in healthy eyes. Older age and longer axial length was sigruficantly associated with CT( all P < 0. 05 ) . Each decade of increasing age was associated with a 8. 62 Vm decrease in CT and each I mm longer axial length , a 12. 70 pdm decrease in CT in healthy eyes. CT was not associated with central corneal thickness and gender. Conclusion Normal CT can be accurately measured by DRI-OCT. Older age and longer axial length are associated with thinner CT.

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备注/Memo

备注/Memo:
 黑龙江省教育厅科学技术研究项目（编号：１２５１１３１１）
更新日期/Last Update: 2015-03-04