[1]孙笑笑,张钰,陈跃国.近视性屈光参差病因学与矫治方法的研究进展[J].眼科新进展,2021,41(4):386-390.[doi:10.13389/j.cnki.rao.2021.0081]
 SUN Xiaoxiao,ZHANG Yu,CHEN Yueguo.Progress in etiology and correction of myopic anisometropia[J].Recent Advances in Ophthalmology,2021,41(4):386-390.[doi:10.13389/j.cnki.rao.2021.0081]
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近视性屈光参差病因学与矫治方法的研究进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
41卷
期数:
2021年4期
页码:
386-390
栏目:
文献综述
出版日期:
2021-04-05

文章信息/Info

Title:
Progress in etiology and correction of myopic anisometropia
作者:
孙笑笑张钰陈跃国
100191 北京市,北京大学第三医院眼科,眼部神经损伤的重建保护与康复 北京市重点实验室
Author(s):
SUN XiaoxiaoZHANG YuCHEN Yueguo
Department of Ophthalmology,Peking University Third Hospital,Beijing Key Laboratory of Restoration of Damaged Ocular Nerve,Beijing 100191,China
关键词:
近视性屈光参差病因学发病机制矫治方法
Keywords:
myopic anisometropiaetiologypathogenesiscorrection
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2021.0081
文献标志码:
A
摘要:
近年来,近视性屈光参差的患病率呈逐年上升趋势。严重的近视性屈光参差可破坏双眼视功能,导致斜视、重度视疲劳等问题,严重影响患者的择业与生活质量。但目前近视性屈光参差的病因和发病机制尚不明确,且防控和矫治近视性屈光参差的重要性常常被忽视。本文将对近年来近视性屈光参差病因学和矫治方法的研究进行综述,为深入认识近视性屈光参差的发病机制和防控措施提供依据。
Abstract:
In recent years, the prevalence of myopic anisometropia is increasing. Severe myopic anisometropia can damage binocular vision, resulting in strabismus, severe asthenopia and other problems, which seriously affect patient’s career and the quality of life. However, the etiology and pathogenesis of myopic anisometropia are still unclear, and the importance of preventing, controlling and correcting myopic anisometropia often be ignored. Therefore, we intend to review the recent research on the etiology, pathogenesis and treatment of myopic anisometropia to provide a basis for further understanding the cause and treatment of myopic anisometropia.

参考文献/References:

[1] DENG L,GWIAZDA J E.Anisometropia in children from infancy to 15 years[J].Invest Ophthalmol Vis Sci,2012,53(7):3782-3787.
[2] LEE C W,FANG S Y,TSAI D C,HUANG N,HSU C C,CHEN S Y,et al.Prevalence and association of refractive anisometropia with near work habits among young schoolchildren:The evidence from a population-based study[J].PLoS One,2017,12(3):e0173519.
[3] HU Y Y,WU J F,LU T L,WU H,SUN W,GUO D D,et al.Prevalence and associations of anisometropia in children[J].Invest Ophthalmol Vis Sci,2016,57(3):979-988.
[4] DE JONG P T,OOSTRA B A,DE FABER J T.High symmetric anisometropia in monozygotic twins[J].Ophthalmic Paediatr Genet,1993,14(1):29-32.
[5] WEISS A H.Unilateral high myopia:optical components,associated factors,and visual outcomes[J].Br J Ophthalmol,2003,87(8):1025-1031.
[6] FENG L,CANDY T R,YANG Y.Severe myopic anisometropia in a Chinese family[J].Optom Vis Sci,2012,89(4):507-511.
[7] SRIKANTH P,LAGOMARSINO V N,PEARSE R V 2nd,LIAO M,GHOSH S,NEHME R,et al.Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression[J].Transl Psychiatry,2018,8(1):245.
[8] FENG L,ZHOU D,ZHANG Z,HE L,LIU Y,YANG Y.Exome sequencing identifies a novel UNC5D mutation in a severe myopic anisometropia family:A case report[J].Medicine (Baltimore),2017,96(24):e7138.
[9] THOMPSON H,CAMAND O,BARKER D,ERSKINE L.Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina[J].J Neurosci,2006,26(31):8082-8091.
[10] LIU K Y,SENGILLO J D,VELEZ G,JAUREGUI R,SAKAI L Y,MAUMENEE I H,et al.Missense mutation in SLIT2 associated with congenital myopia,anisometropia,connective tissue abnormalities,and obesity[J].Orphanet J Rare Dis,2018,13(1):138.
[11] SMITH E L 3RD,HUNG L F,HUANG J,BLASDEL T L,HUMBIRD T L,BOCKHORST K H.Effects of optical defocus on refractive development in monkeys:evidence for local,regionally selective mechanisms[J].Invest Ophthalmol Vis Sci,2010,51(8):3864-3873.
[12] LIU Y,WILDSOET C.The effect of two-zone concentric bifocal spectacle lenses on refractive error development and eye growth in young chicks[J].Invest Ophthalmol Vis Sci,2011,52(2):1078-1086.
[13] ZHANG H Y,LAM C S Y,TANG W C,LEUNG M,TO C H.Defocus incorporated multiple segments spectacle lenses changed the relative peripheral refraction:A 2-year randomized clinical trial[J].Invest Ophthalmol Vis Sci,2020,61(5):53.
[14] BULLIMORE M A,JOHNSON L A.Overnight orthokeratology[J].Cont Lens Anterior Eye,2020,43(4):322-332.
[15] CHO P,TAN Q.Myopia and orthokeratology for myopia control[J].Clin Exp Optom,2019,102(4):364-377.
[16] NA M,YOO A.The effect of orthokeratology on axial length elongation in children with myopia:Contralateral comparison study[J].Jpn J Ophthalmol,2018,62(3):327-334.
[17] TSAI W S,WANG J H,LEE Y C,CHIU C J.Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment[J].J Formos Med Assoc,2019,118(7):1122-1128.
[18] CHU C H,KEE C S.Effects of optically imposed astigmatism on early eye growth in chicks[J].PLoS One,2015,10(2):e0117729.
[19] TWELKER J D,MILLER J M,SHERRILL D L,HARVEY E M.Astigmatism and myopia in Tohono O’odham Native American children[J].Optom Vis Sci,2013,90(11):1267-1273.
[20] WU L,WENG C,XIA F,WANG X,ZHOU X.Internal astigmatism and its role in the growth of axial length in school-age children[J].J Ophthalmol,2018,2018:1686045.
[21] HASHEMI H,KHABAZKHOOB M,EMAMIAN M H,SHARIATI M,ABDOLAHI-NIA T,FOTOUHI A.All biometric components are important in anisometropia,not just axial length[J].Br J Ophthalmol,2013,97(12):1586-1591.
[22] VINCENT S J,COLLINS M J,READ S A,CARNEY L G,YAP M K.Corneal changes following near work in myopic anisometropia[J].Ophthalmic Physiol Opt,2013,33(1):15-25.
[23] HIRAOKA T,KOTSUKA J,KAKITA T,OKAMOTO F,OSHIKA T.Relationship between higher-order wavefront aberrations and natural progression of myopia in schoolchildren[J].Sci Rep,2017,7(1):7876.
[24] LAU J K,VINCENT S J,COLLINS M J,CHEUNG S W,CHO P.Ocular higher-order aberrations and axial eye growth in young Hong Kong children[J].Sci Rep,2018,8(1):6726.
[25] PHILIP K,SANKARIDURG P,HOLDEN B,HO A,MITCHELL P.Influence of higher order aberrations and retinal image quality in myopisation of emmetropic eyes[J].Vision Res,2014,105:233-243.
[26] ZHANG N,YANG X B,ZHANG W Q,LIU L Q,DONG G J,CHEN T W,et al.Relationship between higher-order aberrations and myopia progression in schoolchildren:a retrospective study[J].Int J Ophthalmol,2013,6(3):295-299.
[27] CHARMAN W N.Aberrations and myopia[J].Ophthalmic Physiol Opt,2005,25(4):285-301.
[28] RAMAMIRTHAM R,KEE C S,HUNG L F,QIAO-GRIDER Y,HUANG J,ROORDA A,et al.Wave aberrations in rhesus monkeys with vision-induced ametropias[J].Vision Res,2007,47(21):2751-2766.
[29] HARTWIG A,ATCHISON D A,RADHAKRISHNAN H.Higher-order aberrations and anisometropia[J].Curr Eye Res,2013,38(1):215-219.
[30] VINCENT S J,COLLINS M J,READ S A,CARNEY L G,YAP M K.Interocular symmetry in myopic anisometropia[J].Optom Vis Sci,2011,88(12):1454-1462.
[31] OSUAGWU U L,SUHEIMAT M,ATCHISON D A.Mirror symmetry of peripheral monochromatic aberrations in fellow eyes of isomyopes and anisomyopes[J].Invest Ophthalmol Vis Sci,2016,57(7):3422-3428.
[32] CHIA A,JAURIGUE A,GAZZARD G,WANG Y,TAN D,STONE R A,et al.Ocular dominance,laterality,and refraction in Singaporean children[J].Invest Ophthalmol Vis Sci,2007,48(8):3533-3536.
[33] LINKE S J,BAVIERA J,MUNZER G,STEINBERG J,RICHARD G,KATZ T.Association between ocular dominance and spherical/astigmatic anisometropia,age,and sex:analysis of 10,264 myopic individuals[J].Invest Ophthalmol Vis Sci,2011,52(12):9166-9173.
[34] ITO M,SHIMIZU K,KAWAMORITA T,ISHIKAWA H,SUNAGA K,KOMATSU M.Association between ocular dominance and refractive asymmetry[J].J Refract Surg,2013,29(10):716-720.
[35] WANG Q,WU Y,LIU W,GAO L.Dominant eye and visual evoked potential of patients with myopic anisometropia[J].Biomed Res Int,2016,2016:5064892.
[36] JIANG F,CHEN Z,BI H,EKURE E,SU B,WU H,et al.Association between ocular sensory dominance and refractive error asymmetry[J].PLoS One,2015,10(8):e0136222.
[37] JIANG S,CHEN Z,BI H,XIA R,SHEN T,ZHOU L,et al.Elucidation of the more myopic eye in anisometropia:the interplay of laterality,ocular dominance,and anisometropic magnitude[J].Sci Rep,2019,9(1):9598.
[38] TROILO D,TOTONELLY K,HARB E.Imposed anisometropia,accommodation,and regulation of refractive state[J].Optom Vis Sci,2009,86(1):E31-39.
[39] CHEN A H,AHMAD A,KEARNEY S,STRANG N.The influence of age,refractive error,visual demand and lighting conditions on accommodative ability in Malay children and adults[J].Graefes Arch Clin Exp Ophthalmol,2019,257(9):1997-2004.
[40] LIN Z,VASUDEVAN B,LIANG Y B,ZHANG Y C,ZHAO S Q,YANG X D,et al.Nearwork-induced transient myopia (NITM) in anisometropia[J].Ophthalmic Physiol Opt,2013,33(3):311-317.
[41] PUCKER A D,JACKSON A R,MCHUGH K M,MUTTI D O.Morphological ciliary muscle changes associated with form deprivation-induced myopia[J].Exp Eye Res,2020,193:107963.
[42] LIN L L,LUE C L.Traumatic cycloplegia and myopic anisometropia[J].J Ocul Pharmacol Ther,1996,12(1):45-50.
[43] WAGNER S,SCHAEFFEL F,ZRENNER E,STRABER T.Prolonged nearwork affects the ciliary muscle morphology[J].Exp Eye Res,2019,186:107741.
[44] WAGNER S,ZRENNER E,STRASSER T.Emmetropes and myopes differ little in their accommodation dynamics but strongly in their ciliary muscle morphology[J].Vision Res,2019,163:42-51.
[45] KUCHEM M K,SINNOTT L T,KAO C Y,BAILEY M D.Ciliary muscle thickness in anisometropia[J].Optom Vis Sci,2013,90(11):1312-1320.
[46] BAYRAMLAR H,CEKI O,HEP EN I F.Does convergence,not accommodation,cause axial-length elongation at near? A biometric study in teens[J].Ophthalmic Res,1999,31(4):304-308.
[47] BHARADWAJ S R,CANDY T R.The effect of lens-induced anisometropia on accommodation and vergence during human visual development[J].Invest Ophthalmol Vis Sci,2011,52(6):3595-3603.
[48] PANG Y,FRANTZ K A,ROBERTS D K.Association of refractive error with optic nerve hypoplasia[J].Ophthalmic Physiol Opt,2015,35(5):570-576.
[49] WILDSOET C,WALLMAN J.Choroidal and scleral mechanisms of compensation for spectacle lenses in chicks[J].Vision Res,1995,35(9):1175-1194.
[50] DILLINGHAM C M,GUGGENHEIM J A,ERICHSEN J T.The effect of unilateral disruption of the centrifugal visual system on normal eye development in chicks raised under constant light conditions[J].Brain Struct Funct,2017,222(3):1315-1330.
[51] LONG W,LI Z,HU Y,CUI D,ZHAI Z,YANG X.Pattern of axial length growth in children myopic anisometropes with orthokeratology treatment[J].Curr Eye Res,2020,45(7):834-838.
[52] ZHANG Y,CHEN Y.Effect of orthokeratology on axial length elongation in anisomyopic children[J].Optom Vis Sci,2019,96(1):43-47.
[53] LAM C S Y,TANG W C,TSE D Y,LEE R P K,CHUN R K M,HASEGAWA K,et al.Defocus incorporated multiple segments (DIMS) spectacle lenses slow myopia progression:a 2-year randomised clinical trial[J].Br J Ophthalmol,2020,104(3):363-368.
[54] LAM C S Y,TANG W C,QI H,RADHAKRISHNAN H,HASEGAWA K,TO C H,et al.Effect of defocus incorporated multiple segments spectacle lens wear on visual function in myopic Chinese children[J].Transl Vis Sci Technol,2020,9(9):11.
[55] BERNTSEN D A,BARR C D,MUTTI D O,ZADNIK K.Peripheral defocus and myopia progression in myopic children randomly assigned to wear single vision and progressive addition lenses[J].Invest Ophthalmol Vis Sci,2013,54(8):5761-5770.
[56] BERNTSEN D A,SINNOTT L T,MUTTI D O,ZADNIK K.A randomized trial using progressive addition lenses to evaluate theories of myopia progression in children with a high lag of accommodation[J].Invest Ophthalmol Vis Sci,2012,53(2):640-649.
[57] ZHONG Y,KE L,QIONG W,LIU F.Orthokeratology lens for management of myopia in anisometropic children:A contralateral study[J].Cont Lens Anterior Eye,2020,43(1):40-43.
[58] TSAI W S,WANG J H,CHIU C J.A comparative study of orthokeratology and low-dose atropine for the treatment of anisomyopia in children[J].Sci Rep,2020,10(1):14176.
[59] REMN L,PREZ-MERINO P,MACEDO-DE-ARA U ′ JO R J,AMORIM-DE-SOUSA A I,GONZLEZ-MIJOME J M.Bifocal and multifocal contact lenses for presbyopia and myopia control[J].J Ophthalmol,2020,2020:8067657.
[60] LI S M,KANG M T,WU S S,MENG B,SUN Y Y,WEI S F,et al.Studies using concentric ring bifocal and peripheral add multifocal contact lenses to slow myopia progression in school-aged children:a meta-analysis[J].Ophthalmic Physiol Opt,2017,37(1):51-59.
[61] CHAMBERLAIN P,PEIXOTO-DE-MATOS S C,LOGAN N S,NGO C,JONES D,YOUNG G.A 3-year randomized clinical trial of misight lenses for myopia control[J].Optom Vis Sci,2019,96(8):556-567.
[62] RUIZ-POMEDA A,VILLA-COLLAR C.Slowing the progression of myopia in children with the misight contact lens:A narrative review of the evidence[J].Ophthalmol Ther,2020,9(4):783-795.
[63] LIN L,LAN W,LIAO Y,ZHAO F,CHEN C,YANG Z.Treatment outcomes of myopic anisometropia with 1% atropine:a pilot study[J].Optom Vis Sci,2013,90(12):1486-1492.
[64] MRAVICIC I,BOHAC M,LUKACEVIC S,JAGARIC K,MAJA M,PATEL S.The relationship between clinical measures of aniseikonia and stereoacuity before and after LASIK[J].J Optom,2020,13(1):59-68.
[65] SHAPIRA Y,VAINER I,MIMOUNI M,LEVARTOVSKY S,SELA T,MUNZER G,et al.Effect of anisometropia on the predictability and accuracy of refractive surgery[J].Cornea,2016,35(11):1410-1415.
[66] LIU H,CHEN Q,LAN F,LUO Y,LIN E,LUO W,et al.The modulation of laser refractive surgery on sensory eye dominance of anisometropia[J].J Ophthalmol,2020,2020:3873740.
[67] FENG L,LIN H,CHEN Y,WANG J,WANG Y,LIAO R,et al.The effect of Lasik surgery on myopic anisometropes’ sensory eye dominance[J].Sci Rep,2017,7(1):3629.

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备注/Memo

备注/Memo:
首都卫生发展科研专项基金(编号:首发2018-2-4092)
更新日期/Last Update: 2021-04-05