[1]向菁,康丽华,管怀进.LncRNA在眼科疾病发生发展中的作用机制研究进展[J].眼科新进展,2017,37(6):579-582.[doi:10.13389/j.cnki.rao.2017.0147]
　XIANG Jing,KANG Li-Hua,GUAN Huai-Jin.Research progress on mechanism of lncRNA in ophthalmology disease[J].Recent Advances in Ophthalmology,2017,37(6):579-582.[doi:10.13389/j.cnki.rao.2017.0147]
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LncRNA在眼科疾病发生发展中的作用机制研究进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年6期
页码:
579-582
栏目:
文献综述
出版日期:
2017-06-05

文章信息/Info

Title:
Research progress on mechanism of lncRNA in ophthalmology disease
作者:
向菁; 康丽华; 管怀进
226001　江苏省南通市，南通大学附属医院眼科
Author(s):
XIANG Jing; KANG Li-Hua; GUAN Huai-Jin
Department of Ophthalmology，Affiliated Hospital of Nantong University，Nantong 226001，Jiangsu Province，China
关键词:
LncRNA; 眼科; 进展
Keywords:
LncRNA; ophthalmology; progress
分类号:
R77
DOI:
10.13389/j.cnki.rao.2017.0147
文献标志码:
A
摘要:
长链非编码RNA（long non-coding RNA，lncRNA）在生物体内广泛存在，其作为一种转录长度超过200 bp的非编码RNA，可以调控表观遗传学、转录及转录后水平的基因表达，进而影响细胞的增殖、凋亡、活性、免疫应答及氧化应激。近年来基于lncRNA在眼科学研究中进展迅速，本文主要就lncRNA在眼科疾病发生发展中的作用机制最新研究进展予以综述。
Abstract:
Long non-coding RNA (lncRNA) widely exists in living organisms.It，whose length is more than 200 bp，can regulate the genic expression in the epigenetic，transcriptional and post-transcriptional level.Therefore，it can influence cell proliferation，apoptosis，vitality，immune response and oxidative stress.In recent years，the study of lncRNA is developing rapidly in the ophthalmic research，and this article reviews the latest research progress on mechanism of lncRNA in the ophthalmology disease.

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备注/Memo

备注/Memo:
国家自然科学基金资助（编号：81470616）
更新日期/Last Update: 2017-06-28