[1]刘江,文杭,项敏泓.眼部成纤维细胞在眼科疾病中的研究进展[J].眼科新进展,2021,41(12):1183-1187.[doi:10.13389/j.cnki.rao.2021.0247]
 LIU Jiang,WEN Hang,XIANG Minhong.Research progress in ocular fibroblasts[J].Recent Advances in Ophthalmology,2021,41(12):1183-1187.[doi:10.13389/j.cnki.rao.2021.0247]
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眼部成纤维细胞在眼科疾病中的研究进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
41卷
期数:
2021年12期
页码:
1183-1187
栏目:
文献综述
出版日期:
2021-12-05

文章信息/Info

Title:
Research progress in ocular fibroblasts
作者:
刘江文杭项敏泓
200062 上海市,上海中医药大学附属普陀医院眼科(刘江,项敏泓);200212 上海市,上海中医药大学附属曙光医院眼科(文杭)
Author(s):
LIU Jiang1WEN Hang2XIANG Minhong1
1.Department of Ophthalmology,Putuo Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China
2.Department of Ophthalmology,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200212,China
关键词:
成纤维细胞纤维化细胞培养眼科疾病
Keywords:
fibroblast fibrosis cell culture ophthalmological diseases
分类号:
R771
DOI:
10.13389/j.cnki.rao.2021.0247
文献标志码:
A
摘要:
眼部成纤维细胞的增生、变性是诸多眼部疾病的发病机制之一,如结膜松弛症、翼状胬肉、角膜疾病、青光眼滤过术后的瘢痕化、视网膜疾病、基底细胞癌及Graves眼病等。对眼部成纤维细胞进行体外培养、传代及纯化成功后可广泛应用于相关的实验研究。本文就眼部成纤维细胞的生物学特征、体外培养的方法及其在眼科疾病中的研究进展作一综述。
Abstract:
The proliferation and degeneration of ocular fibroblasts is the main pathogenesis of ocular diseases, such as conjunctivochalasis, pterygium, corneal diseases, scarring after glaucoma filtration surgery, retinal diseases, basal cell carcinoma, and Graves’ ophthalmopathy. The ocular fibroblasts cultured and passaged in vitro can be widely used in related experimental studies after purification. This article reviews the biological characteristics and in vitro culture methods of ocular fibroblasts and the advances in the treatment of ophthalmological diseases.

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备注/Memo

备注/Memo:
国家自然科学基金资助(编号:82074495);上海中医药大学预算内项目(编号:2020LK068);上海市卫生和计划生育委员会科研课题(编号:201840196)
更新日期/Last Update: 2021-12-05