参考文献/References:
[1] RODRIGUES M,KOSARIC N,BONHAM C A,GURTNER G C.Wound healing:a cellular perspective[J].Physiol Rev,2019,99(1):665-706.
[2] KIM H S,PARK S Y,MOON S H,LEE J D,KIM S.Autophagy in human skin fibroblasts:impact of age[J].Int J Mol Sci,2018,19(8):2254.
[3] WOLTERS P J,COLLARD H R,JONES K D.Pathogenesis of idiopathic pulmonary fibrosis[J].Annu Rev Pathol,2014,9:157-179.
[4] TRAVERS J G,KAMAL F A,ROBBINS J,YUTZEY K E,BLAXALL B C.Cardiac fibrosis:the fibroblast awakens[J].Circ Res,2016,118(6):1021-1040.
[5] PAROLA M,PINZANI M.Liver fibrosis:pathophysiology,pathogenetic targets and clinical issues[J].Mol Aspects Med,2019,65:37-55.
[6] LYNCH M D,WATT F M.Fibroblast heterogeneity:implications for human disease[J].J Clin Invest,2018,128(1):26-35.
[7] BASS M D,WILLIAMSON R C,NUNAN R D,HUMPHRIES J D,BYRON A,MORGAN M R,et al.A syndecan-4 hair trigger initiates wound healing through caveolin-and RhoG-regulated integrin endocytosis[J].Dev Cell,2011,21(4):681-693.
[8] 李轶捷,张兴儒,项敏泓,张隆,李青松,韩竹梅.结膜松弛症球结膜成纤维细胞培养的研究[J].国际眼科杂志,2012,12(4):632-635.
LI Y J,ZHANG X R,XIANG M H,ZHANG L,LI Q S,HAN Z M.Cultivation of fibroblasts of bulbar conjunctival in conjunctivochalasis[J].Int Eye Sci,2012,12,12(4):632-635.
[9] SUN N,ZHANG H.Pyroptosis in pterygium pathogenesis[J].Biosci Rep,2018,38(3):BSR20180282.
[10] 刘琳琳,王辉,吴晶,刘锦荣,吴维霖,蒋贻平,等.橙皮苷对人翼状胬肉成纤维细胞增生的抑制作用[J].眼科新进展,2020,40(1):26-30.
LIU L L,WANG H,WU J,LIU J R,WU W L,JIANG Y P,et al.Inhibitory effects of hesperidin on proliferation of human pterygium fibroblasts[J].Rec Adv Ophthalmol,2020,40(1):26-30.
[11] MARMALIDOU A,KHEIRKHAH A,DANA R.Conjunctivochalasis:a systematic review[J].Surv Ophthalmol,2018,63(4):554-564.
[12] MELLER D,LI D Q,TSENG S C.Regulation of collagenase,stromelysin,and gelatinase B in human conjunctival and conjunctivochalasis fibroblasts by interleukin-1beta and tumor necrosis factor-alpha[J].Invest Ophthalmol Vis Sci,2000,41(10):2922-2929.
[13] 李轶捷,张兴儒,项敏泓,俞彰,李青松.结膜松弛症球结膜及筋膜组织的超微结构观察[J].中华实验眼科杂志,2012,30(7):638-640.
LI Y J,ZHANG X R,XIANG M H,YU Z,LI Q S.Ultrastructure change of conjunctiva and fascia tissue of conjunctivochalasis[J].Chin J Exp Ophthalmol,2012,30(7):638-640.
[14] XIANG M H,ZHANG X R,ZHANG Z Y,LI Q S,WANG H M,HAN Z M,et al.Expressions of matrix metalloproteinases 1 and 3 and their tissue inhibitors in the conjunctival tissue and fibroblasts cultured from conjunctivochalasis[J].Int J Ophthalmol,2017,10(4):555-559.
[15] 韩竹梅,张振永,张兴儒,柯梅青,李青松,项敏泓.结膜松弛症患者结膜成纤维细胞中穿透素3和肿瘤坏死因子-α刺激基因6的表达[J].中华实验眼科杂志,2015,33(5):436-439.
HAN Z M,ZHANG Z Y,ZHANG X R,KE M Q,LI Q S,XIANG M H.Expressions of pentraxin-3 and tumor necrosis factor-α stimulated gene-6 proteins in fibroblasts of conjunctivochalasis patients[J].Chin J Exp Ophthalmol,2015,33(5):436-439.
[16] 项敏泓,李轶捷,张兴儒,李青松,韩竹梅,张隆.杞精明目汤药物血清对结膜松弛症患者球结膜成纤维细胞中基质金属蛋白酶表达的影响[J].中华实验眼科杂志,2013,31(10):940-943.
XIANG M H,LI Y J,ZHANG X R,LI Q S,HAN Z M,ZHANG L.Effects of qijingmingmu soup on the expression of matrix metalloproteinases in the conjuntival fibroblasts of conjunctivochalasis[J].Chin J Exp Ophthalmol,2013,31(10):940-943.
[17] 贾元玲,项敏泓,文杭,李青松,詹月萍,黄丽,等.杞精明目汤颗粒剂对肿瘤坏死因子-α刺激下结膜松弛症成纤维细胞MAPK信号通路的影响[J].眼科新进展,2018,38(4):319-323.
JIA Y L,XIANG M H,WEN H,LI Q S,ZHAN Y P,HUANG L,et al.Effect of Qijingmingmu decoction granule on MAPK signal pathway in fibroblasts of conjunctivochalasis stimulated by TNF-α[J].Rec Adv Ophthalmol,2018,38(4):319-323.
[18] LAN W,HOU A,LAKSHMINARAYANAN R,LIM Y P,TONG L.Linc-9432 is a novel pterygium lincRNA which regulates differentiation of fibroblasts[J].FEBS Lett,2018,592(7):1173-1184.
[19] WU Y,LI Z,XIU A Y,MENG D X,WANG S N,ZHANG C Q.Carvedilol attenuates carbon tetrachloride-induced liver fibrosis and hepatic sinusoidal capillarization in mice[J].Drug Des Devel Ther,2019,13:2667-2676.
[20] DERYNCK R,MUTHUSAMY B P,SAETEURN K Y.Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition[J].Curr Opin Cell Biol,2014,31:56-66.
[21] NUWORMEGBE S A,SOHN J H,KIM S W.A PPAR-gamma agonist rosiglitazone suppresses fibrotic response in human pterygium fibroblasts by modulating the p38 MAPK pathway[J].Invest Ophthalmol Vis Sci,2017,58(12):5217-5226.
[22] LEE H,JEONG H,LEE C M,SHIN J A,JANG S W,LEE J H,et al.Antifibrotic effects of Sakuraso-Saponin in primary cultured pterygium fibroblasts in comparison with mitomycin C[J].Invest Ophthalmol Vis Sci,2019,60(14):4784-4791.
[23] 彭娟,毛雁,姚达强,董舒婷,沙翔垠.单侧与双侧翼状胬肉成纤维细胞生物学行为的差异及紫外线对其的影响[J].中华实验眼科杂志,2020,38(5):388-394.
PENG J,MAO Y,YAO D Q,DONG S T,SHA X Y.Difference in cell biological behavior and ultraviolet radiation effect between double-head and unilateral pterygium fibroblasts cultured in vitro[J].Chin J Exp Ophthalmol,2020,38(5):388-394.
[24] HACIO G LU D,ERDL H.Developments and current approaches in the treatment of pterygium[J].Int Ophthalmol,2017,37(4):1073-1081.
[25] YAMANAKA O,KITANO-IZUTANI A,TOMOYOSE K,REINACH P S.Pathobiology of wound healing after glaucoma filtration surgery[J].BMC Ophthalmol,2015,15 (Suppl 1):157.
[26] KOGA Y,MAESHIGE N,TABUCHI H,UEMURA M,AOYAMA-ISHIKAWA M,MIYOSHI M,et al.Suppression of fibrosis in human pterygium fibroblasts by butyrate and phenylbutyrate[J].Int J Ophthalmol,2017,10(9):1337-1343.
[27] CHEN Y Y,TSAI C F,TSAI M C,CHEN W K,HSU Y W,LU F J.Anti-fibrotic effect of rosmarinic acid on inhibition of pterygium epithelial cells[J].Int J Ophthalmol,2018,11(2):189-195.
[28] TAO Y,CHEN Q,ZHAO C,YANG X,CUN Q,YANG W,et al.The in vitro anti-fibrotic effect of Pirfenidone on human pterygium fibroblasts is associated with down-regulation of autocrine TGF-β and MMP-1[J].Int J Med Sci,2020,17(6):734-744.
[29] KIM J W,LIM C W,KIM B.Effects of nicotine on corneal wound healing following acute alkali burn[J].PLoS One,2017,12(6):e0179982.
[30] WILSON S E,MEDEIROS C S,SANTHIAGO M R.Pathophysiology of corneal scarring in persistent epithelial defects after PRK and other corneal injuries[J].J Refract Surg,2018,34(1):59-64.
[31] MORGAN S R,DOOLEY E P,KAMMA-LORGER C,FUNDERBURGH J L,FUNDERBURGH M L,MEEK K M.Early wound healing of laser in situ keratomileusis-like flaps after treatment with human corneal stromal stem cells[J].J Cataract Refract Surg,2016,42(2):302-309.
[32] WILSON S E.Coordinated modulation of corneal scarring by the epithelial basement membrane and descemet’s basement membrane[J].J Refract Surg,2019,35(8):506-516.
[33] LUFT N,SCHUMANN R G,DIRISAMER M,KOOK D,SIEDLECKI J,WERTHEIMER C,et al.Wound healing,inflammation,and corneal ultrastructure after SMILE and femtosecond laser-assisted LASIK:a human ex vivo study[J].J Refract Surg,2018,34(6):393-399.
[34] YUASA Y,SUGIMOTO Y,HIROOKA K,OHKUBO S,HIGASHIDE T,SUGIYAMA K,et al.Effectiveness of trabeculectomy with mitomycin C for glaucomatous eyes with low intraocular pressure on treatment eye drops[J].Acta Ophthalmol,2020,98(1):e81-e87.
[35] LINDEMANN F,PLANGE N,KUERTEN D,SCHIMITZEK H,KOUTSONAS A.Three-year follow-up of trabeculectomy with 5-Fluorouracil[J].Ophthalmic Res,2017,58(2):74-80.
[36] CHEN C Z,RAGHUNATH M.Focus on collagen:in vitro systems to study fibrogenesis and antifibrosis state of the art[J].Fibrogenesis Tissue Repair,2009(1):7.
[37] SAHAY P,REDDY S,PRUSTY B K,MODAK R,RAO A.TGFβ1,MMPs and cytokines profiles in ocular surface:possible tear biomarkers for pseudoexfoliation[J].PLoS One,2021,16(4):e0249759.
[38] KOZDON K,CARIDI B,DURU I,EZRA D G,PHILLIPS J B,BAILLY M.A tenon’s capsule/bulbar conjunctiva interface biomimetic to model fibrosis and local drug delivery[J].PLoS One,2020,15(11):e0241569.
[39] 晏维玲,廖荣丰,李宁.正常人眼结膜成纤维细胞转化为肌成纤维细胞过程中p53的表达变化及其对微小RNA-29b表达的影响[J].中华实验眼科杂志,2018,36(9):676-681.
YAN W L,LIAO R F,LI N.Expression of p53 and its effect on microRNA-29b expression in the process of normal human conjunctival fibroblasts transforming to myofibroblast[J].Chin J Exp Ophthalmol,2018,36(9):676-681.
[40] 邰雪,申颖,赵海霞,王召格,关文英,康欣,等.雷帕霉素在兔眼滤过性手术后的抗瘢痕作用[J].南方医科大学学报,2020,40(9):1346-1352.
TAI X,SHEN Y,ZHAO H X,WANG Z G,GUAN W Y,KANG X,et al.Anti-scarring effect of rapamycin following filtering surgery in rabbit eyes[J].J Southern Med Univ,2020,40(9):1346-1352.
[41] YE S,CHEN Q,JIANG N,LIANG X,LI J,ZONG R,et al.PPARα-dependent effects of palmitoylethanolamide against retinal neovascularization and fibrosis[J].Invest Ophthalmol Vis Sci,2020,61(4):15.
[42] TAMIYA S,KAPLAN H J.Role of epithelial-mesenchymal transition in proliferative vitreoretinopathy[J].Exp Eye Res,2016,142:26-31.
[43] SHU D Y,LOVICU F J.Myofibroblast transdifferentiation:the dark force in ocular wound healing and fibrosis[J].Prog Retin Eye Res,2017,60:44-65.
[44] LITTLE K,MA J H,YANG N,CHEN M,XU H.Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration-the potential sources and molecular cues for their recruitment and activation[J].EBioMedicine,2018,38:283-291.
[45] SINGH A.Systemic changes in neovascular age-related macular degeneration[J].Dan Med J,2014,61(6):B4872.
[46] SHIN J W,KWON S H,CHOI J Y,NA J I,HUH C H,CHOI H R,et al.Molecular mechanisms of dermal aging and antiaging approaches[J].Int J Mol Sci,2019,20(9):2126.
[47] 赵佐芳,王宁,王大庆,兰长骏.眼睑基底细胞癌相关成纤维细胞与正常成纤维细胞形态与生长增殖特性差异[J].眼科新进展,2016,36(4):327-330.
ZHAO Z F,WANG N,WANG D Q,LAN C J.Differences in cellular morphology and proliferation of eyelid basal cell carcinoma associated fibroblasts and normal fibroblasts[J].Rec Adv Ophthalmol,2016,36(4):327-330.
[48] CHEN M,XU G,FAN M,JIA H,XIAO L,LANG J.Anti-tumour effects of a xenogeneic fibroblast activation protein-based whole cell tumour vaccine in murine tumour models[J].Artif Cells Nanomed Biotechnol,2019,47(1):4182-4193.
[49] KHONG J J,MCNAB A A,EBELING P R,CRAIG J E,SELVA D.Pathogenesis of thyroid eye disease:review and update on molecular mechanisms[J].Br J Ophthalmol,2016,100(1):142-150.
[50] TSAI C C,WU S B,KAU H C,WEI Y H.Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts[J].Sci Rep,2018,8(1):7276.
[51] LONGO C M,HIGGINS P J.Molecular biomarkers of Graves’ophthalmopathy[J].Exp Mol Pathol,2019,106:1-6.
[52] DIK W A,VIRAKUL S,VAN STEENSEL L.Current perspectives on the role of orbital fibroblasts in the pathogenesis of Graves’ophthalmopathy[J].Exp Eye Res,2016,142:83-91.
相似文献/References:
[1]唐敏 席兴华 唐罗生 岳丽菁.人羊膜匀浆提取液对兔角膜成纤维细胞增殖和TGF-β1mRNA表达的影响[J].眼科新进展,2013,33(11):000.
[2]张敏,储三军,曾繁星,等. Bevacizumab对视网膜色素上皮细胞纤维化相关因子表达的影响[J].眼科新进展,2014,34(4):318.[doi:10.13389/j.cnki.rao.2014.0086]
[3]张海江,霍鸣,董洁玉,等.核心蛋白多糖抑制翼状胬肉成纤维细胞增生的实验研究[J].眼科新进展,2014,34(8):725.[doi:10.13389/j.cnki.rao.2014.0198]
ZHANG Hai-Jiang,HUO Ming,DONG Jie-Yu,et al.Inhibitive effects of Decorin on proliferation of cultured human pterygium fibroblasts[J].Recent Advances in Ophthalmology,2014,34(12):725.[doi:10.13389/j.cnki.rao.2014.0198]
[4]王冬杰,李宁东,韩瑞芳.遗传眼病永生化细胞系建立方法[J].眼科新进展,2014,34(12):1114.[doi:10.13389/j.cnki.rao.2014.0309]
WANG Dong-Jie,LI Ning-Dong,HAN Rui-Fang.Establishment of immortalized cell lines for genetic eye diseases[J].Recent Advances in Ophthalmology,2014,34(12):1114.[doi:10.13389/j.cnki.rao.2014.0309]
[5]王春明,冯宇梁,李佳,等. 年龄相关性黄斑变性治疗药物研究进展及未来研发方向[J].眼科新进展,2015,35(6):597.[doi:10.13389/j.cnki.rao.2015.0162]
WANG Chun-Ming,FENG Yu-Liang,LI Jia,et al. Progress in drug treatment development for age-related macular degeneration[J].Recent Advances in Ophthalmology,2015,35(12):597.[doi:10.13389/j.cnki.rao.2015.0162]
[6]赵佐芳,王宁,王大庆,等.眼睑基底细胞癌相关成纤维细胞与正常成纤维细胞形态与生长增殖特性差异[J].眼科新进展,2016,36(4):327.[doi:10.13389/j.cnki.rao.2016.0088]
ZHAO Zuo-Fang,WANG Ning,WANG Da-Qing,et al.Differences in cellular morphology and proliferation of eyelid basal cell carcinoma associated fibroblasts and normal fibroblasts[J].Recent Advances in Ophthalmology,2016,36(12):327.[doi:10.13389/j.cnki.rao.2016.0088]
[7]武朋朋,高晓唯,郭继华,等.基质蛋白Fibulin-5在眼眶IgG4相关性疾病中的表达[J].眼科新进展,2016,36(12):1121.[doi:10.13389/j.cnki.rao.2016.0299]
WU Peng-Peng,GAO Xiao-Wei,GUO Ji-Hua,et al.Expression of matrix protein Fibulin-5 in orbital IgG4-related ocular diseases[J].Recent Advances in Ophthalmology,2016,36(12):1121.[doi:10.13389/j.cnki.rao.2016.0299]
[8]饶婷,章余兰.苦参碱对兔眼小梁切除术后滤过泡瘢痕的影响[J].眼科新进展,2017,37(5):428.[doi:10.13389/j.cnki.rao.2017.0108]
RAO Ting,ZHANG Yu-Lan.Effects of matrine on filtering bleb scarring after trabeculectomy in rabbit eyes[J].Recent Advances in Ophthalmology,2017,37(12):428.[doi:10.13389/j.cnki.rao.2017.0108]
[9]崔丽珺,孙娜,田蕴霖,等.TGF-β2刺激人Tenon囊成纤维细胞生物学行为改变及表达整合素连接激酶(ILK)的研究[J].眼科新进展,2017,37(7):605.[doi:10.13389/j.cnki.rao.2017.0154]
CUI Li-Jun,SUN Na,TIAN Yun-Lin,et al.Biological behavior changes and intergrin-linked kinase (ILK) expression after exposure to TGF-β2 in human Tenon fibroblasts[J].Recent Advances in Ophthalmology,2017,37(12):605.[doi:10.13389/j.cnki.rao.2017.0154]
[10]贾元玲,项敏泓,文杭,等.杞精明目汤颗粒剂对肿瘤坏死因子-α刺激下结膜松弛症成纤维细胞MAPK信号通路的影响[J].眼科新进展,2018,38(4):319.[doi:10.13389/j.cnki.rao.2018.0075]
JIA Yuan-Ling,XIANG Min-Hong,WEN Hang,et al.Effect of Qijingmingmu decoction granule on MAPK signal pathway in fibroblasts of conjunctivochalasis stimulated by TNF-α[J].Recent Advances in Ophthalmology,2018,38(12):319.[doi:10.13389/j.cnki.rao.2018.0075]