参考文献/References:
[1] MORGAN I G,FRENCH A N,ASHBY R S,GUO X,DING X,HE M, et al.The epidemics of myopia: Aetiology and prevention[J].Prog Retin Eye Res,2018,62:134-149.
[2] HOLDEN B A,FRICKE T R,WILSON D A,JONG M,NAIDOO K S,SANKARIDURG P, et al.Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050[J].Ophthalmology,2016,123(5):1036-1042.
[3] DOLGIN E.The myopia boom[J].Nature,2015,519(7543):276-278.
[4] JOACHIMSEN L,BOHRINGER D,GROSS N J,REICH M,STIFTER J,REINHARD T,et al.A pilot study on the efficacy and safety of 0.01% atropine in german school children with progressive myopia[J].Ophthalmol Ther,2019,8(3):427-433.
[5] SACCHI M,SERAFINO M,VILLANI E,TAGLIABUE E,LUCCARELLI S,BONSIGNORE F,et al.Efficacy of atropine 0.01% for the treatment of childhood myopia in European patients[J].Acta Ophthalmol,2019,97(8):e1136-e1140.
[6] QIAN L,ZHAO H,LI X,YIN J,TANG W,CHEN P,et al.Pirenzepine inhibits myopia in guinea pig model by regulating the balance of MMP-2 and TIMP-2 expression and increased tyrosine hydroxylase levels[J].Cell Biochem Biophys,2015,71(3):1373-1378.
[7] VUTIPONGSATORN K,YOKOI T,OHNO-MATSUI K.Current and emerging pharmaceutical interventions for myopia[J].Br J Ophthalmol,2019,103(11):1539-1548.
[8] LUU C D,FOO H,CREWTHER S G,GREWTHER D P.Effects of a non-steroidal (ketorolac tromethamine) and a steroidal (dexamethasone) anti-inflammatory drug on refractive state and ocular growth[J].Clin Exp Ophthalmol,2001,29(3):175-178.
[9] ZHAO F,ZHOU Q,REINACH P S,YANG J,MA L,WANG X,et al.Cause and effect relationship between changes in scleral matrix metallopeptidase-2 expression and myopia development in mice[J].Am J Pathol,2018,188(8):1754-1767.
[10] LIU H H,KENNING M S,JOBLING A I,MCBRIEN N A,GENTLE A.Reduced scleral TIMP-2 expression is associated with myopia development: TIMP-2 supplementation stabilizes scleral biomarkers of myopia and limits myopia development[J].Invest Ophthalmol Vis Sci,2017,58(4):1971-1981.
[11] JIA Y,YUE Y,HU D N,CHEN J L,ZHOU J B.Human aqueous humor levels of transforming growth factor-beta2: Association with matrix metalloproteinases/tissue inhibitors of matrix metalloproteinases[J].Biomed Rep,2017,7(6):573-578.
[12] CHEN B Y,WANG C Y,CHEN W Y,MA J X.Altered TGF-beta2 and bFGF expression in scleral desmocytes from an experimentally-induced myopia guinea pig model[J].Graefes Arch Clin Exp Ophthalmol,2013,251(4):1133-1144.
[13] 刘蓓,张磊,刘玉震,高洪莲,隋文君.康柏西普对兔眼准分子激光角膜切削术术后角膜上皮下雾状混浊的影响[J].中华实验眼科杂志,2019,37(2):94-100.
LIU B,ZHANG L,LIU Y Z,GAO H L,SUI W J.Effects of conbercept on haze formation after photorefractive keratectomy in rabbit eyes[J].Chin J Exp Ophthalmol,2019,37(2):94-100.
[14] CAMPBELL I C,HANNON B G,READ A T,SHERWOOD J M,SCHWANER S A,ETHIER C R.Quantification of the efficacy of collagen cross-linking agents to induce stiffening of rat sclera[J].J R Soc Interface,2017,14(129): 20170014.
[15] JIA Y,HU D N,ZHU D,ZHANG L,GU P,FAN X,et al.MMP-2,MMP-3,TIMP-1,TIMP-2,and TIMP-3 protein levels in human aqueous humor: relationship with axial length[J].Invest Ophthalmol Vis Sci,2014,55(6):3922-3928.
[16] WU H,CHEN W,ZHAO F,ZHOU Q,REINACH P S,DENG L,et al.Scleral hypoxia is a target for myopia control[J].Proc Natl Acad Sci U S A,2018,115(30):E7091-E7100.
[17] XI L Y,YIP S P,SHAN S W,SUMMERS-RADA J,KEE C S.Region-specific differential corneal and scleral mRNA expressions of MMP2,TIMP2,and TGFβ2 in highly myopic-astigmatic chicks[J].Sci Rep,2017,7(1):11423.
[18] LI T,ZHOU X,LI B,JIANG B.Effect of MT3 on retinal and choroidal TGF-beta2 and HAS2 expressions in form deprivation myopia of guinea pig[J].J Ophthalmol,2017,2017:5028019.
[19] MAO J,ZHANG C,LIU C,SHEN L,LAO L,SHAO Y,et al.The efficacy of intravitreal conbercept for chronic central serous chorioretinopathy[J].J Ophthalmol,2019,2019:7409426.
[20] DE OLIVEIRA D J,DE ANDRADE G C,NOVAIS E A,FARAH M E,RODRIGUES E B.Fusion proteins for treatment of retinal diseases: aflibercept,ziv-aflibercept, and conbercept[J].Int J Retina Vitreous,2016,2:3.
[21] CAI S,YANG Q,LI X,ZHANG Y.The efficacy and safety of aflibercept and conbercept in diabetic macular edema[J].Drug Des Devel Ther,2018,12:3471-3483.
[22] LAZZARA F,FIDILIO A,PLATANIA C,GIURDANELLA G,SALOMONE S,LEGGIO G M,et al.Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway[J].Biochem Pharmacol,2019,168:341-351.
[23] FOROOGHIAN F,KERTES P J,ENG K T,ALBIANI D A,KIRKER A W,MERKUR A B,et al.Alterations in intraocular cytokine levels following intravitreal ranibizumab[J].Can J Ophthalmol,2016,51(2):87-90.
[24] 张兰兰,刘琼,于健,唐晓娟,徐静.转化生长因子-β(TGF-β)影响豚鼠巩膜成纤维细胞增殖和α-平滑肌肌动蛋白(α-SMA)表达的研究[J].眼科新进展,2016,36(11):1011-1015.
ZHANG L L,LIU Q,YU J,TANG X J,XU J.Effects of TGF-β on cellular proliferation and α-SMA expression in guinea pig scleral fibroblasts[J].Rec Adv Ophthalmol,2016,36(11):1011-1015.
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