[1]韩梦雨,金明,王志军.炎性细胞因子与新生血管性眼病[J].眼科新进展,2017,37(11):1088-1092.[doi:10.13389/j.cnki.rao.2017.0275]
　HAN Meng-Yu,JIN Ming,WANG Zhi-Jun.Inflammatory cytokines in neovascular eye diseases[J].Recent Advances in Ophthalmology,2017,37(11):1088-1092.[doi:10.13389/j.cnki.rao.2017.0275]
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炎性细胞因子与新生血管性眼病/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年11期
页码:
1088-1092
栏目:
文献综述
出版日期:
2017-11-05

文章信息/Info

Title:
Inflammatory cytokines in neovascular eye diseases
作者:
韩梦雨; 金明; 王志军
100029　北京市，北京中医药大学（韩梦雨，金明）；100029　北京市，中日友好医院眼科（金明，王志军）
Author(s):
HAN Meng-Yu; JIN Ming; WANG Zhi-Jun
Beijing University of Chinese Medicine（HAN Meng-Yu，JIN Ming），Beijing 100029，China；Department of Ophthalmology，China-Japan Friendship Hospital（JIN Ming，WANG Zhi-Jun），Beijing 100029，China
关键词:
新生血管性眼病; 肿瘤坏死因子-α; 白细胞介素-1; 白细胞介素-6; 白细胞介素-18
Keywords:
neovascular eye diseases; TNF-α; IL-1; IL-6; IL-18
分类号:
R77
DOI:
10.13389/j.cnki.rao.2017.0275
文献标志码:
A
摘要:
新生血管性眼病是引起人类不可逆视力损害的主要病因。尽管眼内抗血管内皮生长因子药物治疗已成为临床中新生血管性眼病的重要疗法之一，但该疗法本身疗效不稳定且存在诸多的潜在风险和并发症。因此探寻更明确有效的治疗靶点是必要的。研究表明，肿瘤坏死因子-α、白细胞介素-1、白细胞介素-6和白细胞介素-18等炎性细胞因子与新生血管性眼病关系密切，本文就近些年来与新生血管性眼病相关的炎性细胞因子作一综述。
Abstract:
Neovascular eye diseases are the leading cause of irreversible visual impairment in humans.Although intraocular anti-vascular endothelial growth factor therapy has become one of the most important treatments for these disease，the treatment itself is not stable and there are many potential risks and complications.So it is necessary to explore a clearer and more effective therapeutic target.Studies have shown that the inflammatory cytokines，especially TNF-α，IL-1，IL-6 and IL-18，are closely related to the onset of neovascular eye diseases.Therefore，a review on inflammatory cytokines in neovascular eye diseases will present in this article.

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更新日期/Last Update: 2017-11-01