[1]滕娟,陈小红,陈梅珠,等.非增生型糖尿病视网膜病变患者黄斑水肿与中心凹下脉络膜厚度的关系[J].眼科新进展,2017,37(3):244-247.[doi:10.13389/j.cnki.rao.2017.0061]
　TENG Juan,CHEN Xiao-Hong,CHEN Mei-Zhu,et al.Relationship between macular edema and subfoveal choroidal thickness in patients with non proliferative diabetic retinopathy[J].Recent Advances in Ophthalmology,2017,37(3):244-247.[doi:10.13389/j.cnki.rao.2017.0061]
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非增生型糖尿病视网膜病变患者黄斑水肿与中心凹下脉络膜厚度的关系/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年3期
页码:
244-247
栏目:
应用研究
出版日期:
2017-03-05

文章信息/Info

Title:
Relationship between macular edema and subfoveal choroidal thickness in patients with non proliferative diabetic retinopathy
作者:
滕娟; 陈小红; 陈梅珠; 王云鹏; 余海跃
233000　安徽省蚌埠市，蚌埠市第二人民医院眼科（滕娟）；350025　福建省福州市，福州总医院，厦门大学附属东方医院，福建医科大学福总临床医学院（陈小红，陈梅珠，王云鹏，余海跃）
Author(s):
TENG Juan; CHEN Xiao-Hong; CHEN Mei-Zhu; WANG Yun-Peng; YU Hai-Yue
Department of Ophthalmology，the Second People’s Hospital of Bengbu City(TENG Juan)，Bengbu 233000，Anhui Province，China；Department of Ophthalmology，Fuzhou General Hospital，Dongfang Hospital Affiliated to Xiamen University，Clinical Medical College of Fujian Medical University(CHEN Xiao-Hong，CHEN Mei-Zhu，WANG Yun-Peng，YU Hai-Yue)，Fuzhou 350025，Fujian Province，China
关键词:
脉络膜; 光学相干断层扫描; 非增生型糖尿病视网膜病变; 黄斑水肿
Keywords:
choroid; optical coherence tomography; non-proliferative diabetic retinopathy; macular edema
分类号:
R774
DOI:
10.13389/j.cnki.rao.2017.0061
文献标志码:
A
摘要:
目的　观察非增生型糖尿病视网膜病变（non-proliferative diabetic retinopathy，NPDR）伴临床有意义的黄斑水肿（clinically significant macular edema，CSME）时黄斑中心凹下脉络膜厚度（subfoveal choroidal thickness，SFCT）的情况，探讨糖尿病患者SFCT与糖尿病视网膜病变发生发展的关系。方法　按2014年我国糖尿病视网膜病变临床诊疗指南分期标准将NPDR患者分为伴CSME（NPDR CSME+）组15例（21眼），不伴CSME（NPDR CSME-）组21例（36眼）。比较两组之间最佳矫正视力、黄斑中心凹视网膜厚度（central retinal thickness，CRT）及SFCT是否存在差异性。采用SPSS 18.0软件进行统计学分析处理。结果　NPDR CSME+组与NPDR CSME-组间性别、眼别、年龄、眼轴长度、眼压相比差异均无统计学意义(均为P＞0.05)，两组间最佳矫正视力相比差异有统计学意义(P=0.001)。NPDR CSME+组SFCT为（328.24±101.92）μm，NPDR CSME-组为（235.31±66.98）μm，两组间差异具有统计学意义（t=4.156，P=0.000）。NPDR患眼CRT与SFCT呈正相关关系（r=0.473，P=0.000）。结论　NPDR伴有CSME时，SFCT显著增厚，并且SFCT的增厚与CSME的发生发展具有一定相关性。
Abstract:
Objective　To observe the changes of subfoveal choroidal thickness (SFCT) in diabetic patients with non-proliferative diabetic retinopathy (NPDR) and clinically significant macular edema(CSME),and then investigate diabetic SFCT and the relationship of diabetic CT with diabetic retinopathy(DR).Methods　The patients were divided into 2 groups according to clinical guidelines of DR in China in 2014,including NPDR CSME+group(21 eyes) and NPDR CSME-group(36 eyes).All patients were underwent best corrected visual acuity (BCVA),intraocular pressure,axial length,slit lamp microscope,indirect ophthalmoscope,EDI-OCT examination,and mean arterial blood pressure measurement.The differences of BCVA,central retinal thickness（CRT）and SFCT between NPDR CSME+group and NPDR CSME-group were studied as well by means of using SPSS 18.0 for data statistics.Results　There was no significant difference in gender,age,eye axis and intraocular pressure between NPDR CSME+group and NPDR CSME-group (all P>0.05).There was significant difference in BCVA between the two groups (P=0.001).The mean SFCT were (328.24±101.92) μm in the NPDR CSME+group and (235.31±66.98)μm in the NPDR CSME-group,and the difference was statistically significant (t=4.156,P=0.000).And plotting changes in CRT against changes in SFCT in patients with CSME revealed a positive correlation(r=0.473,P=0.000).Conclusion　SFCT in NPDR CSME+ patient is thicker than that in NPDR CSME-patient.And plotting changes in CRT against changes in SFCT in patients with CSME reveals a positive correlation.

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备注/Memo

备注/Memo:
全军医药卫生科研重大项目（编号：15ZD041）；福建省科技厅重点项目（编号：2016Y0067）
更新日期/Last Update: 2017-04-01