[1]汪思瑶,梁双凤,郭玉娟,等.基于多光谱屈光地形图的儿童青少年视网膜周边离焦研究[J].眼科新进展,2024,44(5):396-400.[doi:10.13389/j.cnki.rao.2024.0077]
　WANG Siyao,LIANG Shuangfeng,GUO Yujuan,et al.Peripheral retinal defocus in adolescents based on multispectral refraction topography[J].Recent Advances in Ophthalmology,2024,44(5):396-400.[doi:10.13389/j.cnki.rao.2024.0077]
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基于多光谱屈光地形图的儿童青少年视网膜周边离焦研究/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
44卷
期数:
2024年5期
页码:
396-400
栏目:
应用研究
出版日期:
2024-04-30

文章信息/Info

Title:
Peripheral retinal defocus in adolescents based on multispectral refraction topography
作者:
汪思瑶; 梁双凤; 郭玉娟; 李羽; 周跃华
610075　四川省成都市，成都中医药大学眼科学院（汪思瑶，梁双凤，郭玉娟，李羽，周跃华）；100062　北京市，北京茗视光眼科（汪思瑶，梁双凤，郭玉娟，李羽，周跃华）；610084　四川省成都市，成都中医大银海眼科医院（汪思瑶，梁双凤，郭玉娟，李羽，周跃华）
Author(s):
WANG Siyao1; 2; 3; LIANG Shuangfeng1; 2; 3; GUO Yujuan1; 2; 3; LI Yu1; 2; 3; ZHOU Yuehua1; 2; 3
1.Eye School of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,Sichuan Province,China
2.Beijing Ming Vision Ophthalmology Hospital,Beijing 100062,China
3.Ineye Hospital of Chengdu University of TCM，Chengdu 610084,Sichuan Province,China
关键词:
多光谱屈光地形图; 视网膜离焦; 近视; 儿童青少年
Keywords:
multispectral refraction topography;  retinal defocus;  myopia;  adolescent
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2024.0077
文献标志码:
A
摘要:
目的　探究视网膜周边离焦与儿童青少年近视的关系。
方法　纳入2022年10月至2023年4月在成都中医大银海眼科医院就诊的8~15岁儿童青少年192例（192眼，均取右眼），根据等效球镜度(SE)分为正视组、低度近视组和中度近视组，每组各64例(64眼)。散瞳验光，并以SE记录；IOL Master 900检测生物学参数，包括眼轴长度（AL）、中央角膜厚度（CCT）、晶状体厚度（LT）、角膜曲率值［水平角膜曲率值（K1）和垂直角膜曲率值（K2）］；采用多光谱屈光地形图测量视网膜离焦量，正值为远视性离焦，负值为近视性离焦。以黄斑中心凹为圆心，视网膜总离焦记录为TRDV；环形区域分为0°~10°、>10°~20°、>20°~30°、>30°~40°、>40°~53°，分别记录为RDV-0°~10°、RDV-10°~20°、RDV-20°~30°、RDV-30°~40°、RDV-40°~53°；象限区域分为上侧、下侧、颞侧、鼻侧，分别记录为RDV-S、RDV-I、RDV-T、RDV-N。通过单因素方差分析和非参数检验分析不同范围离焦量的差异；Spearman和Pearson相关性分析SE、AL与离焦量的关系。
结果　正视组、低度近视组和中度近视组受检者的RDV-20°~30°、RDV-30°~40°、RDV-40°~53°均为远视性离焦。三组受检者TRDV、RDV-10°~20°、RDV-20°~30°、RDV-30°~40°、RDV-40°~53°、RDV-S、RDV-T、RDV-N相比，差异均有统计学意义(均为P<0.05）。TRDV、RDV-20°~30°、RDV-30°~40°、RDV-40°~53°、RDV-S、RDV-T、RDV-N与SE均呈负相关，与AL均呈正相关（均为P<0.05）；RDV-0°~10°、RDV-I与SE、AL均不相关（均为P>0.05）;RDV-10°~20°与AL呈正相关（P=0.012)，与SE不相关（P=0.233)。
结论　视网膜周边远视性离焦随着偏心度和近视程度增大而增大。视网膜离焦具有不对称性。周边（10°~53°）、上侧、鼻侧、颞侧视网膜离焦可能与近视进展密切相关。
Abstract:
Objective　To explore the association between peripheral retinal defocus and myopia in adolescents.
Methods　This study encompassed 192 adolescents (192 right eyes), aged between eight and fifteen years, who sought treatment at Ineye Hospital of Chengdu University of TCM from October 2022 to April 2023. Based on the spherical equivalent (SE), the patients were divided into three groups: Emmetropia (E), low myopia (LM), and moderate myopia (MM), with each group comprising 64 patients (64 right eyes). After mydriatic refraction, the SE values were documented. Ocular biological parameters, including axial length (AL), central corneal thickness (CCT), lens thickness (LT), and keratometry values (K1, K2), were obtained using IOL Master 900. Multispectral refraction topography was employed to measure the retinal defocus: positive values indicated hyperopic defocus, while negative ones represented myopic defocus. With the macular fovea as the center, the total retinal defocus value was recorded as TRDV. The ring partition (eccentricity) was divided into 0°- 10°、>10°-20°、>20°-30°、>30°-40°、>40°-53° ,which was recorded as RDV-0°-10°, RDV-10°-20°, RDV-20°-30°, RDV-30°-40°, and RDV-40°-53°, respectively; the quadrants were recorded as RDV-Superior (RDV-S), RDV-Inferior (RDV-I), RDV-Temporal (RDV-T) and RDV-Nasal (RDV-N), respectively. The variance of RDV across different ranges was analyzed using One-Way ANOVA and non-parametric tests. The associations between SE, AL and RDV were examined using Spearman and Pearson correlation analyses.
Results　The RDV-20°-30°, RDV-30°-40°and RDV-40°-53°of Groups E, LM and MM all exhibited hyperopic defocus. Statistically significant differences were identified in TRDV, RDV-10°-20°, RDV-20°-30°, RDV-30°-40°, RDV-40°-53°, RDV-S, RDV-T and RDV-N among the three groups (all P<0.05). TRDV, RDV-20°-30°, RDV-30°-40°, RDV-40°-53°, RDV-S, RDV-T, and RDV-N were found to be negatively correlated with SE while positively correlated with AL (all P<0.05). RDV-0°-10° and RDV-I were uncorrelated with both SE and AL (all P>0.05); RDV-10°-20° was positively correlated with AL (P=0.012) while uncorrelated with SE (P=0.233).
Conclusion　Peripheral retinal hyperopic defocus tends to advance with escalating eccentricity and myopia. Peripheral retinal defocus is asymmetrical. Peripheral (10°-53°), superior, nasal and temporal retinal defocus may be closely related to the development of myopia.

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更新日期/Last Update: 2024-05-05