SHI Yongwei,BI Hongsheng,JIANG Wenjun.Research progress in the relationship between transforming growth factor-β2 and eye diseases[J].Recent Advances in Ophthalmology,2023,43(5):407-411.[doi:10.13389/j.cnki.rao.2023.0082]





Research progress in the relationship between transforming growth factor-β2 and eye diseases
250014 山东省济南市,山东中医药大学(石永伟);250002 山东省济南市,山东省中西医结合眼病防治重点实验室,山东省高校中西医结合眼病防治技术(强化)重点实验室,山东省眼病防治研究院,山东中医药大学附属眼科医院(毕宏生,蒋文君)
SHI Yongwei1BI Hongsheng2JIANG Wenjun2
1.Shandong University of Traditional Chinese Medicine,Jinan 250014
2.Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Shandong,Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases,Institute of Ophthalmology Disease Prevention and Control of Shandong,Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250002
transforming growth factor-β2 epithelial-mesenchymal transition extracellular matrix eye diseases
Transforming growth factor-β2 (TGF-β2) is expressed in many ocular tissues, including the cornea, sclera and retina and plays a vital role in the proliferation, differentiation and metastasis of ocular tissue cells. Recent research has shown that TGF-β2 can participate in disease pathogenesis through biological processes such as epithelial-mesenchymal transition and extracellular matrix remodeling, and it is closely related to various eye diseases such as glaucoma, fibrotic cataracts, corneal injury, proliferative vitreoretinopathy, and myopia. This paper reviews the role and mechanism of TGF-β2 in various eye diseases.


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更新日期/Last Update: 2023-05-16