[1]金拓,高卫萍.代谢组学在干眼研究中的应用进展[J].眼科新进展,2022,42(4):329-332.[doi:10.13389/j.cnki.rao.2022.0066]
　JIN Tuo,GAO Weiping.Advances in the application of metabolomics in dry eye research[J].Recent Advances in Ophthalmology,2022,42(4):329-332.[doi:10.13389/j.cnki.rao.2022.0066]
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代谢组学在干眼研究中的应用进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
42卷
期数:
2022年4期
页码:
329-332
栏目:
文献综述
出版日期:
2022-04-05

文章信息/Info

Title:
Advances in the application of metabolomics in dry eye research
作者:
金拓; 高卫萍
210029　江苏省南京市，南京中医药大学附属医院眼科
Author(s):
JIN Tuo; GAO Weiping
Department of Ophthalmology,Affiliated Hospital,Nanjing University of Chinese Medicine,Nanjing 210029,Jiangsu Province,China
关键词:
代谢组学; 干眼; 综述; 代谢标志物
Keywords:
metabolomics;  dry eye;  review;  metabolic marker
分类号:
R777.2
DOI:
10.13389/j.cnki.rao.2022.0066
文献标志码:
A
摘要:
干眼是近年来临床眼科医师普遍关注的眼表疾病，其症状主要为眼睛干涩、异物感或灼热感，常会影响患者的日常生活、学习、工作等。干眼的发病机制十分复杂，目前仍未完全清楚。代谢组学是一门研究代谢产物的变化规律并揭示生命活动本质的科学。通过分析干眼患者独特的代谢产物和综合代谢状况，人们可能发现其潜在的发病机制。这有助于发现针对干眼更有效的预防和治疗措施。本文综述了代谢组学在干眼研究中的应用进展，并提出了未来研究的方向。
Abstract:
Dry eye is an ocular surface disease of concern by ophthalmologists in recent years. It shows symptoms of eye dryness, foreign body sensation or burning sensation which have affected patients’ daily life, study and work. However, the pathogenesis of dry eye is complex and still not clear. Metabolomics is a science that studies the changes in metabolites and reveals the nature of vital activities. By analyzing the unique metabolites and comprehensive metabolic conditions of dry eye patients, researchers may discover its underlying pathogenesis. This could be helpful to figure out more effective preventions and therapies for dry eye. This paper reviews the progress of metabolomics in dry eye research and suggests future research directions.

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备注/Memo

备注/Memo:
国家自然科学基金项目（编号：82074526）
更新日期/Last Update: 2022-04-05