[1]杜倩,路迎龙,李筱荣,等.梅毒性巩膜炎的临床特征与治疗[J].眼科新进展,2017,37(5):455-457.[doi:10.13389/j.cnki.rao.2017.0115]
　DU Qian,LU Ying-Long,LI Xiao-Rong,et al.Clinical features and treatment of syphilitic scleritis[J].Recent Advances in Ophthalmology,2017,37(5):455-457.[doi:10.13389/j.cnki.rao.2017.0115]
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梅毒性巩膜炎的临床特征与治疗/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年5期
页码:
455-457
栏目:
应用研究
出版日期:
2017-05-05

文章信息/Info

Title:
Clinical features and treatment of syphilitic scleritis
作者:
杜倩; 路迎龙; 李筱荣; 张晓敏
300384　天津市，天津医科大学眼科医院
Author(s):
DU Qian; LU Ying-Long; LI Xiao-Rong; ZHANG Xiao-Min
Eye Hospital of Tianjin Medical University，Tianjin 300384，China
关键词:
梅毒性巩膜炎; 后部鳞状脉络膜视网膜病变; 梅毒性葡萄膜炎
Keywords:
syphilis scleritis; posterior placoid chorioretinitis; syphilis uveitis
分类号:
R772.3
DOI:
10.13389/j.cnki.rao.2017.0115
文献标志码:
A
摘要:
目的　分析总结梅毒性巩膜炎患者的临床特征及治疗结果。方法　对我院2011年至2016年确诊的梅毒性巩膜炎患者临床资料进行回顾性研究，对梅毒性巩膜炎的临床特征及预后结果进行评价与分析。结果　7例（7眼）患者经临床及血清学检查确诊为梅毒性巩膜炎。所有患者就诊前未知梅毒感染，有3例患者眼部是唯一的临床表现。梅毒血清学检查包括梅毒快速血浆反应素试验及梅毒螺旋体颗粒凝集试验，两者均为阳性。所有患者HIV检测均为阴性，排除HIV感染。7例患者均为单眼发病，病程1周～2 a。患者均以不同程度的眼红、眼痛伴视力下降等为主诉就诊。患者中2例为前部浅层巩膜炎，3例为前部结节性前巩膜炎，1例为弥漫性前巩膜炎，1例为弥漫性表层巩膜炎伴有急性梅毒性后部鳞状脉络膜视网膜病变。所有患者均接受青霉素治疗，治疗后巩膜炎症均完全消退。结论　梅毒感染性巩膜炎较少见且易被误诊，主要表现为各种类型的前部巩膜炎。对于可疑病例要进行梅毒血清学检测以明确诊断。正确驱梅治疗后，患者预后较好。
Abstract:
Objective　To summarize and describe clinical features and treatment outcome of syphilitic scleritis．Methods　A retrospective study was conducted in patients diagnosed as syphilitic scleritis from 2011 to 2016 in our hospital.Clinical characteristics and prognosis were evaluated.Results　Seven patients （7 eyes） were diagnosed as syphilitic scleritis by clinical and serological examinations.All patients were unaware that they had syphilis infection before visit.The ocular manifestation was the only clinical findings in three patients.Both treponema pallidum particle agglutination and rapid plasma regain were positive.Meanwhile，the scleritis infection was excluded，tests for human immunodeficiency virus （HIV） were negative．Syphilitic scleritis was unilateral in all patients，and the duration was from one week to two years.Initial symptoms were varied in degree of ocular redness，pain and visual impairment.Two patients presented with anterior episcleritis，nodular anterior scleritis was found in three patients，one patient showed diffuse anterior scleritis，and one patient presented with diffuse episcleritis combined with acute syphilitic posterior placoid chorioretinitis.All patients were treated with penicillin G，and inflammation resolved quickly after treatment.Conclusion　Syphilitic scleritis is rare and ease to be misdiagnosed，various types of anterior scleritis is the main manifestation.Syphilitic serologic test should be performed for the suspected cases.The prognosis is well with anti-syphilis therapy.

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更新日期/Last Update: 2017-06-07