[1]肖蓓,宋艳萍,闫明,等.阈值下微脉冲激光治疗多模式成像分类的中心性浆液性脉络膜视网膜病变的疗效观察[J].眼科新进展,2024,44(7):531-535.[doi:10.13389/j.cnki.rao.2024.0102]
 XIAO Bei,SONG Yanping,YAN Ming,et al.Observation on the efficacy of subthreshold micropulse laser photocoagulation in the treatment of central serous chorioretinopathy based on multimodal imaging classification[J].Recent Advances in Ophthalmology,2024,44(7):531-535.[doi:10.13389/j.cnki.rao.2024.0102]
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阈值下微脉冲激光治疗多模式成像分类的中心性浆液性脉络膜视网膜病变的疗效观察/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
44卷
期数:
2024年7期
页码:
531-535
栏目:
应用研究
出版日期:
2024-07-01

文章信息/Info

Title:
Observation on the efficacy of subthreshold micropulse laser photocoagulation in the treatment of central serous chorioretinopathy based on multimodal imaging classification
作者:
肖蓓宋艳萍闫明叶娅黄珍陈丛邓玉梦
510515 广东省广州市,南方医科大学第一临床医学院(肖蓓,宋艳萍);430070 湖北省武汉市,中国人民解放军中部战区总医院眼科(肖蓓,宋艳萍,闫明,叶娅,黄珍,陈丛,邓玉梦)
Author(s):
XIAO Bei12SONG Yanping12YAN Ming2YE Ya2HUANG Zhen2CHEN Cong2DENG Yumeng2
1.The First School of Clinical Medicine,Southern Medical University,Guangzhou 510515,Guangdong Province,China
2.Department of Ophthalmology,General Hospital of Central Theater Command,Wuhan 430070,Hubei Province,China
关键词:
中心性浆液性脉络膜视网膜病变微脉冲激光光凝视网膜下液多模式成像
Keywords:
central serous chorioretinopathy micropulse laser photocoagulation subretinal fluid multimodal imaging
分类号:
R773.4
DOI:
10.13389/j.cnki.rao.2024.0102
文献标志码:
A
摘要:
目的 观察577 nm阈值下微脉冲激光光凝(SMLP)对中心性浆液性脉络膜视网膜病变(CSC)的疗效,探究新的多模式成像分类CSC的基线特征和预后特点。
方法 回顾性分析2017年6月至2022年5月于中国人民解放军中部战区总医院眼科确诊的CSC患眼44例(46眼),依据新的多模式成像分类分为单纯性CSC组(23眼)和复杂性CSC组(23眼),所有患眼均使用577 nm SMLP治疗。比较两组患眼基线及治疗后 1、3、6个月最佳矫正视力(BCVA)、黄斑中心凹视网膜厚度(CMT)的变化,同时观察基线及随访6个月后两组CSC患眼组内、组间变化及视网膜下液(SRF)的完全吸收率。
结果 单纯性CSC组患眼的 BCVA治疗后6个月较基线时明显提高(P=0.010);复杂性 CSC组患眼的BCVA治疗后3、6个月均较基线时明显提高(均为P<0.01)。单纯性CSC组患眼的CMT治疗后1、3、6个月均较基线时显著降低(均为P<0.05);复杂性CSC组患眼的CMT治疗后 1、6个月均较基线显著降低(均为P<0.05);单纯性CSC组患眼治疗后6个月较基线时CMT的改变量为(-163.74±88.10)μm,复杂性CSC组患眼为(-71.96±164.30)μm,两组相比差异有统计学意义(P=0.023)。随访期间,单纯性CSC组患眼持续性SRF眼数明显低于复杂性CSC组(P<0.05)。单纯性CSC组患眼治疗后6个月的SRF完全吸收率大于复杂性CSC组(P<0.05)。
结论 577 nm SMLP治疗单纯性CSC的预后优于复杂性CSC,新的基于多模式成像分类CSC对预测SMLP治疗的预后具有一定价值。
Abstract:
Objective To observe the efficacy of 577 nm subthreshold micropulse laser photocoagulation (SMLP) on central serous chorioretinopathy (CSC) and explore the baseline characteristics and prognostic features of multimodal imaging-based CSC.
Methods A retrospective analysis was conducted on 44 patients (46 eyes) with CSC diagnosed at the Ophthalmology Department of the General Hospital of Central Theater Command, PLA from June 2017 to May 2022. The patients were classified into the simple CSC group (23 eyes) and the complex CSC group (23 eyes) based on the multimodal imaging classification. All patients underwent 577 nm SMLP treatment. The best corrected visual acuity (BCVA) and central macular thickness (CMT) of patients between the two groups were compared before treatment and at 1, 3 and 6 months after treatment. The intra-group and inter-group changes and the complete absorption rate of subretinal fluid (SRF) in CSC eyes of patients between the two groups were assessed before treatment and at 6 months after follow-up.
Results The BCVA of patients in the simple CSC group significantly improved at 6 months after treatment compared with the baseline (P=0.010); the BCVA of patients in the complex CSC group significantly improved at 3 and 6 months after treatment compared with the baseline (both P<0.01). The CMT of patients in the simple CSC group was significantly lower than the baseline at 1, 3, and 6 months after treatment (all P<0.05); the CMT of patients in the complex CSC group was significantly lower than the baseline at 1 and 6 months after treatment (both P<0.05); the change in CMT from baseline after 6 months of treatment for simple CSC was (-163.74±88.10) μm, the change in CMT from baseline after 6 months of treatment for complex CSC was (-71.96±164.30) μm, and the difference between the two groups was statistically significant (P=0.023). During the follow-up period, the number of eyes with persistent SRF in the simple CSC group was significantly lower than that in the complex CSC group (P<0.05). The complete absorption rate of SRF at 6 months after treatment in the simple CSC group was greater than that in the complex CSC group (P<0.05).
Conclusion The prognosis of simple CSC treated with 577 nm SMLP is better than that of complex CSC, and the new multimodal imaging classification has a certain value in predicting the prognosis of CSC after SMLP.

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备注/Memo

备注/Memo:
国家重点研发计划“常见多发病防治研究”重点专项(编号:2022YFC2502800)
更新日期/Last Update: 2024-07-05