[1]任章军,余进海,桑泽曦,等.人工智能深度学习在眼眶病及眼肿瘤疾病诊疗中的应用研究现状[J].眼科新进展,2024,44(2):163-168.[doi:10.13389/j.cnki.rao.2024.0032]
 REN Zhangjun,YU Jinhai,SANG Zexi,et al.Research advancement of the application of artificial intelligence deep learning in the diagnosis and treatment of orbital diseases and ocular tumors[J].Recent Advances in Ophthalmology,2024,44(2):163-168.[doi:10.13389/j.cnki.rao.2024.0032]
点击复制

人工智能深度学习在眼眶病及眼肿瘤疾病诊疗中的应用研究现状/HTML
分享到:

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
44卷
期数:
2024年2期
页码:
163-168
栏目:
文献综述
出版日期:
2024-01-26

文章信息/Info

Title:
Research advancement of the application of artificial intelligence deep learning in the diagnosis and treatment of orbital diseases and ocular tumors
作者:
任章军余进海桑泽曦王耀华廖洪斐
330006 江西省南昌市,南昌大学附属眼科医院眼科
Author(s):
REN ZhangjunYU JinhaiSANG ZexiWANG YaohuaLIAO Hongfei
Department of Ophthalmology,the Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China
关键词:
眼眶病眼肿瘤深度学习人工智能
Keywords:
orbital disease ocular tumor deep learning artificial intelligence
分类号:
R770.4
DOI:
10.13389/j.cnki.rao.2024.0032
文献标志码:
A
摘要:
近年来,深度学习作为人工智能机器学习的关键分支,在医学领域的应用取得了显著进展。它通过分析医学图像,实现了多种疾病的准确检测、诊断和预后评估。在眼科领域,深度学习技术已经广泛应用于甲状腺相关眼病、眼眶爆裂性骨折、黑色素瘤、基底细胞癌、眼眶脓肿、淋巴瘤、视网膜母细胞瘤等疾病的诊断和预测。这项技术利用计算机断层扫描、磁共振成像甚至病理切片等获得的图像,能够高度准确地进行眼眶病及眼肿瘤疾病的诊断、鉴别和分期分类,其准确度已足以与专业医师媲美。这一技术的应用前景巨大,有望提升相关疾病的诊疗水平,同时减少临床实践所需的时间和成本。本综述汇总了近年来关于人工智能深度学习在眼眶病及眼肿瘤疾病领域应用的最新研究进展,旨在为临床医师提供有关这一领域的最新信息和发展趋势,并进一步促进该技术的临床应用及普及推广。
Abstract:
In recent years, deep learning, a pivotal subset of artificial intelligence machine learning, has achieved noteworthy advancements in the medical domain. It facilitates precise detection, diagnosis and prognostic assessment of various diseases through the analysis of medical images. Within ophthalmology, deep learning techniques have found widespread application in the diagnosis and prediction of thyroid-related eye diseases, orbital blowout fracture, melanoma, basal cell carcinoma, orbital abscess, lymphoma, retinoblastoma and other diseases. Leveraging images from computed tomography, magnetic resonance imaging and even pathological sections, this technology demonstrates a capacity to diagnose, differentiate and stage orbital diseases and ocular tumors with a high level of accuracy comparable to that of expert clinicians. The promising prospects of this technology are expected to enhance the diagnosis and treatment of related diseases, concurrently reducing the time and cost associated with clinical practices. This review consolidates the latest research progress on the application of artificial intelligence deep learning in orbital diseases and ocular tumors, aiming to furnish clinicians with up-to-date information and developmental trends in this field, thereby furthering the clinical application and widespread adoption of this technology.

参考文献/References:

[1] KOSEOGLU N D,CORRA Z M,ALVIN LIU T Y A.Artificial intelligence for ocular oncology[J].Curr Opin Ophthalmol,2023,34(5):437-440.
[2] NAM J G,PARK S,HWANG E J,LEE J H,JIN K N,LIM K Y,et al.Development and validation of deep learning-based automatic detection algorithm for malignant pulmonary nodules on chest radiographs[J].Radiology,2019,290(1):218-228.
[3] GAO X W,HUI R,TIAN Z.Classification of CT brain images based on deep learning networks[J].Comput Meth Programs Biomed,2017,138:49-56.
[4] BALKENENDE L,TEUWEN J,MANN R M.Application of deep learning in breast cancer imaging[J].Semin Nucl Med,2022,52(5):584-596.
[5] JEON H B,KANG D H,OH S A,GU J H.Comparative study of naugle and hertel exophthalmometry in orbitozygomatic fracture[J].J Craniofacial Surg,2016,27(1):142-144.
[6] NIGHTINGALE C L,SHAKIB K.Analysis of contemporary tools for the measurement of enophthalmos:a PRISMA-driven systematic review[J].Br J Oral Maxillofac Surg,2019,57(9):904-912.
[7] ZHANG Y,RAO J,WU X,ZHOU Y,LIU G,ZHANG H.Automatic measurement of exophthalmos based orbital CT images using deep learning [J].Front Cell Dev Biol,2023,11:1135959.
[8] HANAI,TABUCHI H,NAGASATO D,TANABE M,MASUMOTO H,MIYA S,et al.Automated detection of enlarged extraocular muscle in Graves’ ophthalmopathy with computed tomography and deep neural network[J].Sci Rep,2022,12(1):16036.
[9] ROSSIN E J,SZYPKO C,GIESE I,HALL N,GARDINER M F,LORCH A.Factors associated with increased risk of serious ocular injury in the setting of orbital fracture[J].JAMA Ophthalmol,2021,139(1):77.
[10] CHEPURNYI Y,CHERNOHORSKYI D,PRYKHODKO D,POUTALA A,KOPCHAK A.Reliability of orbital volume measurements based on computed tomography segmentation:validation of different algorithms in orbital trauma patients[J].J Craniomaxillofac Surg,2020,48(6):574-581.
[11] KIM M J,LEE M J,JEONG W S,HONG H,CHOI J W.Three-dimensional computer modeling of standard orbital mean shape in Asians[J].J Plast Reconstr Aesthetic Surg,2020,73(3):548-555.
[12] XU J,ZHANG D,WANG C,ZHOU H,LI Y,CHEN X.Automatic segmentation of orbital wall from CT images via a thin wall region supervision-based multi-scale feature search network[J].Int J Comput Assist Radiol Surg,2023,18(11):2051-2062.
[13] KHAN S N,SEPAHDARI A R.Orbital masses:CT and MRI of common vascular lesions,benign tumors,and malignancies[J].Saudi J Ophthalmol,2012,26(4):373-383.
[14] SHAO J,ZHU J,JIN K,GUAN X,JIAN T,XUE Y,et al.End-to-end deep-learning-based diagnosis of benign and malignant orbital tumors on computed tomography images[J].J Pers Med,2023,13(2):204.
[15] AYDIN N,SAYLISOY S,CELIK O,ASLAN A,ODABAS A.Segmentation of orbital and periorbital lesions detected in orbital magnetic resonance imaging by deep learning method[J].Pol J Radiol,2022,87(1):e516-e520.
[16] AHMED B,QADIR M I,GHAFOOR S.Malignant melanoma:skin cancer-diagnosis,prevention,and treatment[J].Crit Rev Eukaryot Gene Expr,2020,30(4):291-297.
[17] WANG L,DING L,LIU Z,SUN L,CHEN L,JIA R,et al.Automated identification of malignancy in whole-slide pathological images:identification of eyelid malignant melanoma in gigapixel pathological slides using deep learning[J].Br J Ophthalmol,2020,104(3):318-323.
[18] LUO Y,ZHANG J,YANG Y,RAO Y,CHEN X,SHI T,et al.Deep learning-based fully automated differential diagnosis of eyelid basal cell and sebaceous carcinoma using whole slide images[J].Quant Imaging Med Surg,2022,12(8):4166-4175.
[19] YOO T K,CHOI J Y,KIM H K,RYU I H,KIM J K.Adopting low-shot deep learning for the detection of conjunctival melanoma using ocular surface images[J].Comput Methods Programs Biomed,2021,205:106086.
[20] ADIL E A,MUIR M E,KAWAI K,DOMBROWSKI N D,CUNNINGHAM M J.Pediatric subperiosteal abscess secondary to acute sinusitis:a systematic review and meta-analysis[J].Laryngoscope,2020,130(12):2906-2912.
[21] FU R,LEADER J K,PRADEEP T,SHI J,MENG X,ZHANG Y,et al.Automated delineation of orbital abscess depicted on CT scan using deep learning[J].Med Phys,2021,48(7):3721-3729.
[22] LI E Y,YUEN H K,CHEUK W.Lymphoproliferative disease of the orbit[J].Asia Pac J Ophthalmol,2015,4(2):106-111.
[23] BRANNAN P A.A review of sclerosing idiopathic orbital inflammation[J].Curr Opin Ophthalmol,2007,18(5):402-404.
[24] LAMBIN P,RIOS-VELAZQUEZ E,LEIJENAAR R,CARVALHO S,VAN STIPHOUT R G,GRANTON P,et al.Radiomics:extracting more information from medical images using advanced feature analysis[J].Eur J Cancer,2012,48(4):441-446.
[25] WOOLF D K,AHMED M,PLOWMAN P N.Primary lymphoma of the ocular adnexa (orbital lymphoma) and primary intraocular lymphoma[J].Clin Oncol,2012,24(5):339-344.
[26] MAYERHOEFER M E,MATERKA A,LANGS G,HGGSTRM I,SZCZYPIN'SKI P,GIBBS P,et al.Introduction to radiomics[J].J Nucl Med,2020,61(4):488-495.
[27] XIE X,YANG L,ZHAO F,WANG D,ZHANG H,HE X,et al.A deep learning model combining multimodal radiomics,clinical and imaging features for differentiating ocular adnexal lymphoma from idiopathic orbital inflammation[J].Eur Radiol,2022,32(10):6922-6932.
[28] SALFRANT M,GARCIA G C T E,GUICHARD J P,BIDAULT F,REIZINE D,AUPRIN A,et al.Imaging of skull base and orbital invasion in sinonasal cancer:correlation with histopathology[J].Cancers,2021,13(19):4963.
[29] NAKAGAWA J,FUJIMA N,HIRATA K,TANG M,TSUNETA S,SUZUKI J,et al.Utility of the deep learning technique for the diagnosis of orbital invasion on CT in patients with a nasal or sinonasal tumor[J].Cancer Imaging,2022,22(1):52.
[30] KALIKI S,SHIELDS C L,SHIELDS J A.Uveal melanoma:estimating prognosis[J].Indian J Ophthalmol,2015,63(2):93-102.
[31] RANTALA E S,HERNBERG M M,PIPERNO-NEUMANN S,GROSSNIKLAUS H E,KIVEL T T.Metastatic uveal melanoma:the final frontier[J].Prog Retin Eye Res,2022,90:101041.
[32] ZHANG H,LIU Y,ZHANG K,HUI S,FENG Y,LUO J,et al.Validation of the relationship between iris color and uveal melanoma using artificial intelligence with multiple paths in a large Chinese population[J].Front Cell Dev Biol,2021,9:713209.
[33] JAGER M J,SHIELDS C L,CEBULLA C M,ABDEL-RAHMAN M H,GROSSNIKLAUS H E,STERN M H,et al.Uveal melanoma[J].Nat Rev Dis Primers,2020,6(1):24.
[34] SUN M,ZHOU W,QI X,ZHANG G,GIRNITA L,SEREGARD S,et al.Prediction of BAP1 expression in uveal melanoma using densely-connected deep classification networks[J].Cancers,2019,11(10):1579.
[35] SHIELDS C,ANCONA-LEZAMA D,DALVIN L.Modern treatment of retinoblastoma:a 2020 review[J].Indian J Ophthalmol,2020,68(11):2356.
[36] STRIJBIS V I J,DE BLOEME C M,JANSEN R W,KEBIRI H,NGUYEN H G,DE JONG M C,et al.Multi-view convolutional neural networks for automated ocular structure and tumor segmentation in retinoblastoma[J].Sci Rep,2021,11(1):14590.
[37] KUMAR P,SUGANTHI D,VALARMATHI K,SWAIN M P,VASHISTHA P,BUDDHI D,et al.A multi-thresholding-based discriminative neural classifier for detection of retinoblastoma using CNN models[J].Biomed Res Int,2023,2023:5803661.
[38] TAYLOR P N,ZHANG L,LEE R W J,MULLER I,EZRA D G,DAYAN C M,et al.New insights into the pathogenesis and nonsurgical management of Graves orbitopathy[J].Nat Rev Endocrinol,2020,16(2):104-116.
[39] BARTALENA L,TANDA M L.Current concepts regarding Graves’ orbitopathy[J].J Intern Med,2022,292(5):692-716.
[40] LEI C,QU M,SUN H,HUANG J,HUANG J,SONG X,et al.Facial expression of patients with Graves’ orbitopathy[J].J Endocrinol Invest,2023,46(10):2055-2066.
[41] LEE J,SEO W,PARK J,LIM W S,OH J Y,MOON N J,et al.Neural network-based method for diagnosis and severity assessment of Graves’ orbitopathy using orbital computed tomography[J].Sci Rep,2022,12(1):12071.
[42] LIN C,SONG X,LI L,LI Y,JIANG M,SUN R,et al.Detection of active and inactive phases of thyroid-associated ophthalmopathy using deep convolutional neural network[J].BMC Ophthalmol,2021,21(1):39.
[43] YAO N,LI L,GAO Z,ZHAO C,LI Y,HAN C,et al.Deep learning-based diagnosis of disease activity in patients with Graves’ orbitopathy using orbital SPECT/CT[J].Eur J Nucl Med Mol Imaging,2023,50(12):3666-3674.
[44] DOLMAN P J.Dysthyroid optic neuropathy:evaluation and management[J].J Endocrinol Invest,2021,44(3):421-429.
[45] WU C,LI S,LIU X,JIANG F,SHI B.DMs-MAFM+EfficientNet:a hybrid model for predicting dysthyroid optic neuropathy[J].Med Biol Eng Comput,2022,60(11):3217-3230.
[46] JUREK-MATUSIAK O,BROZ·EK-MADRY E,JASTRZEBSKA H,KRZESKI A.Orbital decompression for thyroid eye disease:surgical treatment outcomes in endocrinological assessment[J].Endokrynol Pol,2021,72(6):609-617.
[47] YOO T K,CHOI J Y,KIM H K.A generative adversarial network approach to predicting postoperative appearance after orbital decompression surgery for thyroid eye disease[J].Comput Biol Med,2020,118:103628.
[48] COHEN J,RAD I.Contemporary management of carotid blowout[J].Curr Opin Otolaryngol Head Neck Surg,2004,12(2):110-115.
[49] LI L,SONG X,GUO Y,LIU Y,SUN R,ZOU H,et al.Deep convolutional neural networks for automatic detection of orbital blowout fractures[J].J Craniofac Surg,2020,31(2):400-403.
[50] BAO X L,ZHAN X,WANG L,ZHU Q,FAN B,LI G Y.Automatic identification and segmentation of orbital blowout fractures based on artificial intelligence[J].Transl Vis Sci Technol,2023,12(4):7.

相似文献/References:

[1]李静,葛心,马建民,等.特发性眼眶炎性假瘤患者血清细胞间黏附分子-1水平及其临床意义[J].眼科新进展,2015,35(1):039.[doi:10.13389/j.cnki.rao.2015.0011]
 LI Jing,GE Xin,MA Jian-Min,et al.Serum ICAM-1 level in idiopathic orbital inflammatory pseudotumor and its clinical significance[J].Recent Advances in Ophthalmology,2015,35(2):039.[doi:10.13389/j.cnki.rao.2015.0011]
[2]李静,葛心,马建民. 泪腺良性淋巴上皮病变免疫组织化学研究[J].眼科新进展,2015,35(5):439.[doi:10.13389/j.cnki.rao.2015.0119]
 LI Jing,GE Xin,MA Jian-Min. Immunohistochemical research on benign lymphoepithelial lesion of lacrimal gland[J].Recent Advances in Ophthalmology,2015,35(2):439.[doi:10.13389/j.cnki.rao.2015.0119]

备注/Memo

备注/Memo:
江西省自然科学基金项目(编号:20232ACB206030)
更新日期/Last Update: 2024-02-05