[1]吴沙,邹梦怡,廖洪斐.miRNA在视网膜母细胞瘤中的作用研究进展[J].眼科新进展,2022,42(1):071-74.[doi:10.13389/j.cnki.rao.2022.0016]
 WU Sha,ZOU Mengyi,LIAO Hongfei.Advances in the role of microRNA in retinoblastoma[J].Recent Advances in Ophthalmology,2022,42(1):071-74.[doi:10.13389/j.cnki.rao.2022.0016]
点击复制

miRNA在视网膜母细胞瘤中的作用研究进展/HTML
分享到:

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
42卷
期数:
2022年1期
页码:
071-74
栏目:
文献综述
出版日期:
2022-01-05

文章信息/Info

Title:
Advances in the role of microRNA in retinoblastoma
作者:
吴沙邹梦怡廖洪斐
330006 江西省南昌市,江西省眼科重点实验室,南昌大学附属眼科医院
Author(s):
WU ShaZOU MengyiLIAO Hongfei
Eye Hospital Affiliated to Nanchang University,Nanchang 330006,Jiangxi Province,China
关键词:
microRNA视网膜母细胞瘤研究进展诊断治疗
Keywords:
microRNA retinoblastoma research progress diagnosis treatment
分类号:
R774
DOI:
10.13389/j.cnki.rao.2022.0016
文献标志码:
A
摘要:
视网膜母细胞瘤(RB)是儿童最常见的原发性眼内恶性肿瘤,其发病与基因突变相关。microRNA(miRNA)是一种非编码RNA,能调控基因的表达,目前已成为肿瘤研究的热点之一。本文将对miRNA在RB中相关研究进展作一综述,从而为RB的诊断、治疗提供新思路和新方法。
Abstract:
Retinoblastoma (RB) is the most common primary intraocular malignancy in children, associated with gene mutation. microRNA is a type of non-coding RNA, which can regulate gene expression. It has become one of the hotspots in cancer research. This article reviews the research progress of microRNA in the RB so as to provide new ideas and methods for the diagnosis and treatment of RB.

参考文献/References:

[1] FABIAN I D,ABDALLAH E,ABDULLAHI S U,ABDULQADER R A,ADAMOU B S,ADEMOLA-POPOOLA D S,et al.Global retinoblastoma presentation and analysis by national income level[J].JAMA Oncol,2020,6(5):685-695.
[2] ALI S Z,LANGDEN S,MUNKHZUL C,LEE M,SONG S J.Regulatory mechanism of microRNA expression in cancer[J].Int J Mol Sci,2020,21(5).
[3] LING H,GIRNITA L,BUDA O,CALIN G A.Non-coding RNAs:the cancer genome dark matter that matters[J].Clin Chem Lab Med,2017,55(5):705-714.
[4] KNUDSON A J.Mutation and cancer:statistical study of retinoblastoma[J].Proc Natl Acad Sci U S A,1971,68(4):820-823.
[5] SILVERA V M,GUERIN J B,BRINJIKJI W,DALVIN L A.Retinoblastoma:what the neuroradiologist needs to know?[J].AJNR Am J Neuroradiol,2021,Online ahead of print.
[6] BORNFELD N,LOHMANN D,BECHRAKIS N E,BIEWALD E.Retinoblastoma[J].Ophthalmologe,2020,117(4):389-402.
[7] RUPAIMOOLE R,SLACK F J.MicroRNA therapeutics:towards a new era for the management of cancer and other diseases[J].Nat Rev Drug Discov,2017,16(3):203-222.
[8] WEI D,MIAO Y,YU L,WANG D,WANG Y.Downregulation of microRNA-198 suppresses cell proliferation and invasion in retinoblastoma by directly targeting PTEN[J].Mol Med Rep,2018,18(1):595-602.
[9] TIAN R,ZOU H,WANG L F,SONG M J,LIU L,ZHANG H.Identification of microRNA-mRNA regulatory networks and pathways related to retinoblastoma across human and mouse[J].Int J Ophthalmol,2020,13(4):535-544.
[10] XU F,LIU G,WANG L,WANG X,JIN X,BO W.miR-494 promotes progression of retinoblastoma via PTEN through PI3K/AKT signaling pathway[J].Oncol Lett,2020,20(2):1952-1960.
[11] LI X,YANG L,SHUAI T,PIAO T,WANG R.MiR-433 inhibits retinoblastoma malignancy by suppressing Notch1 and PAX6 expression[J].Biomed Pharmacother,2016,82:247-255.
[12] BU W,WANG Y,MIN X.MicroRNA-106b promotes the proliferation,migration and invasion of retinoblastoma cells by inhibiting the expression of ZBTB4 protein[J].Exp Ther Med,2018,16(6):4537-4545.
[13] HOPPER K D,SHERMAN J L,BOAL D K,EGGLI K D.CT and MR imaging of the pediatric orbit[J].Radiographics,1992,12(3):485-503.
[14] BETA M,VENKATESAN N,VASUDEVAN M,VETRIVEL U,KHETAN V,KRISHNAKUMAR S.Identification and insilico analysis of retinoblastoma serum microRNA profile and gene targets towards prediction of novel serum biomarkers[J].Bioinform Biol Insights,2013,7:21-34.
[15] LIU S S,WANG Y S,SUN Y F,MIAO L X,WANG J,LI Y S,et al.Plasma microRNA-320,microRNA-let-7e and microRNA-21 as novel potential biomarkers for the detection of retinoblastoma[J].Biomed Rep,2014,2(3):424-428.
[16] ZHENG Q,ZHU Q,LI C,HAO S,LI J,YU X,et al.microRNA-144 functions as a diagnostic and prognostic marker for retinoblastoma[J].Clinics (Sao Paulo),2020,75:e1804.
[17] ZHOU P,LI X.Serum miR-338-5p has potential for use as a tumor marker for retinoblastoma[J].Oncol Lett,2019,18(1):307-313.
[18] RAO R,HONAVAR S G.Retinoblastoma[J].Indian J Pediatr,2017,84(12):937-944.
[19] LIANG Y,CHEN X,LIANG Z.MicroRNA-320 regulates autophagy in retinoblastoma by targeting hypoxia inducible factor-1α[J].Exp Ther Med,2017,14(3):2367-2372.
[20] LI M,ZHANG D,CHENG J,LIANG J,YU F.Ginsenoside Rh2 inhibits proliferation but promotes apoptosis and autophagy by down-regulating microRNA-638 in human retinoblastoma cells[J].Exp Mol Pathol,2019,108:17-23.
[21] WU S,AI N,LIU Q,ZHANG J.MicroRNA 448 inhibits the progression of retinoblastoma by directly targeting ROCK1 and regulating PI3K/AKT signalling pathway[J].Oncol Rep,2018,39(5):2402-2412.
[22] WANG L L,HU H F,FENG Y Q.Suppressive effect of microRNA-143 in retinoblastoma[J].Int J Ophthalmol,2016,9(11):1584-1590.
[23] ZHANG Y,XUE C,ZHU X,ZHU X,XIAN H,HUANG Z.Suppression of microRNA-125a-5p upregulates the TAZ-EGFR signaling pathway and promotes retinoblastoma proliferation[J].Cell Signal,2016,28(8):850-860.
[24] WU S,HAN M,ZHANG C.Overexpression of microRNA-186 inhibits angiogenesis in retinoblastoma via the Hedgehog signaling pathway by targeting ATAD2[J].J Cell Physiol,2019,234(10):19059-19072.
[25] XU H K,WANG X D,WANG D G,WEI D D,LIANG L,LIU C H.miR-340 exerts suppressive effect on retinoblastoma progression by targeting KIF14[J].Curr Eye Res,2021,46(2):232-238.
[26] HUANG Y X,NIE X G,LI G D,FAN D S,SONG L L,ZHANG X L.Downregulation of microRNA-182 inhibits cell viability,invasion and angiogenesis in retinoblastoma through inhibition of the PI3K/AKT pathway and CADM2 upregulation[J].Int J Oncol,2018,53(6):2615-2626.
[27] SONG L,HUANG Y,ZHANG X,HAN S,HOU M,LI H.Downregulation of microRNA-224-3p hampers retinoblastoma progression via activation of the hippo-YAP signaling pathway by increasing LATS2[J].Invest Ophthalmol Vis Sci,2020,61(3):32.
[28] SUN Z,ZHANG A,ZHANG L.Inhibition of microRNA-492 attenuates cell proliferation and invasion in retinoblastoma via directly targeting LATS2[J].Mol Med Rep,2019,19(3):1965-1971.
[29] GUI F,HONG Z,YOU Z,WU H,ZHANG Y.MiR-21 inhibitor suppressed the progression of retinoblastoma via the modulation of PTEN/PI3K/AKT pathway[J].Cell Biol Int,2016,40(12):1294-1302.
[30] DING Y,WU M,LIU J,WU C,HUANG R,ZHU R,et al.Seed-targeting anti-miR-21 inhibiting malignant progression of retinoblastoma and analysis of their phosphorylation signaling pathways[J].Exp Eye Res,2014,122:1-8.
[31] BROWN R,CURRY E,MAGNANI L,WILHELM-BENARTZI C S,BORLEY J.Poised epigenetic states and acquired drug resistance in cancer[J].Nat Rev Cancer,2014,14(11):747-753.
[32] YUAN R,HOU Y,SUN W,YU J,LIU X,NIU Y,et al.Natural products to prevent drug resistance in cancer chemotherapy:a review[J].Ann N Y Acad Sci,2017,1401(1):19-27.
[33] MA J,DONG C,JI C.MicroRNA and drug resistance[J].Cancer Gene Ther,2010,17(8):523-531.
[34] GHASABI M,MANSOORI B,MOHAMMADI A,DUIJF P H,SHOMALI N,SHIRAFKAN N,et al.MicroRNAs in cancer drug resistance:basic evidence and clinical applications[J].J Cell Physiol,2019,234(3):2152-2168.
[35] LIU K,HUANG J,XIE M,YU Y,ZHU S,KANG R,et al.MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell[J].Autophagy,2014,10(3):442-452.
[36] YANG G,FU Y,LU X,WANG M,DONG H,LI Q.miR-34a regulates the chemosensitivity of retinoblastoma cells via modulation of MAGE-A/p53 signaling[J].Int J Oncol,2019,54(1):177-187.
[37] YIN W,GAO F,ZHANG S.MicroRNA-34a inhibits the proliferation and promotes the chemosensitivity of retinoblastoma cells by downregulating Notch1 expression[J].Mol Med Rep,2020,22(2):1613-1620.
[38] YUAN X W,YAN T Q,TONG H.Effect of miR-515-5p on proliferation and drug sensitivity of retinoblastoma cells[J].Cancer Manag Res,2020,12:12087-12098.
[39] LI C,ZHAO J,SUN W.microRNA-222-mediated VHL downregulation facilitates retinoblastoma chemoresistance by increasing HIF1α expression[J].Invest Ophthalmol Vis Sci,2020,61(10):9.

相似文献/References:

[1]刘瑾 朱豫.视网膜母细胞瘤的治疗进展[J].眼科新进展,2013,33(1):000.
[2]常海敏 杨磊 千新来.Calphostin C对人视网膜母细胞瘤细胞增殖的抑制作用[J].眼科新进展,2013,33(9):000.
[3]崔平 南娜 康洁 李军会 申景然.白藜芦醇对人视网膜母细胞瘤细胞侵袭能力的影响及机制研究[J].眼科新进展,2012,32(1):000.
[4]张俊 周琦 吕红彬.MicroRNA 及其在糖尿病视网膜病变中的研究进展[J].眼科新进展,2012,32(2):000.
[5]宋念艺 陈绪涛 张娴.B超、CT及MRI检查在视网膜母细胞瘤诊断中的价值[J].眼科新进展,2012,32(10):000.
[6]张千帆 刘瑞敏 穆红梅 郭洋 申飞 刘莹.白藜芦醇对视网膜母细胞瘤Y79细胞增殖的影响及其机制[J].眼科新进展,2012,32(11):000.
[7]迟源 王海林 谢晚晴 才文卓 才丽平.MicroRNA调节视网膜新生血管研究进展[J].眼科新进展,2013,33(2):000.
[8]兰兰 惠延年 曾光伟.微小RNA与磷酸化胞外信号调节激酶在视网膜母细胞瘤中的表达及其相关性分析[J].眼科新进展,2013,33(6):000.
[9]覃冬菊,唐罗生,游庆华,等.HSP27、增殖细胞核抗原在视网膜母细胞瘤中的表达[J].眼科新进展,2010,30(5):000.
[10]蒋永强 吴晓梅 连金贤.视网膜母细胞瘤术后23 a未复发1例[J].眼科新进展,2009,29(1):000.

备注/Memo

备注/Memo:
国家自然科学基金资助(编号:82060181);江西省重点研发计划基金资助(编号:20181BBG70007)
更新日期/Last Update: 2022-01-05