参考文献/References:
[1] WONG T Y,SUN J,KAWASAKI R,RUAMVIBOONSUK P,GUPTA N,LANSINGH V C,et al.Guidelines on diabetic eye care: The international council of ophthalmology recommendations for screening,follow-up,referral,and treatment based on resource settings[J].Ophthalmology,2018,125(10):1608-1622.
[2] SIVAPRASAD S,AMOAKU W M,HYKIN P,RVO Guideline Group.The Royal College of Ophthalmologists Guidelines on retinal vein occlusions: executive summary[J].Eye,2015,29(12):1633-1638.
[3] SCHMIDT-ERFURTH U,CHONG V,LOEWENSTEIN A,LARSEN M,SOUIED E,SCHLINGEMANN R,et al.Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA) [J].Br J Ophthalmol,2014,98(9):1144-1167.
[4] 卢谦益.阿柏西普经玻璃体内注射治疗糖尿病黄斑水肿的临床疗效[J].眼科新进展, 2019, 39(4) : 340-342.
LU Q Y.Intravitreal aflibercept injection for the treatment of diabetic macular edema[J].Rec Adv Ophthalmol,2019,39(4):340-342.
[5] DE OLIVEIRA DIAS J R,DE ANDRADE G C,NOVAIS E A,FARAH M E,RODRIGUES E B.Fusion proteins for treatment of retinal diseases: aflibercept,ziv-aflibercept,and conbercept[J].Int J Retina Vitreous,2016,2(1):3.
[6] SUN Z,ZHOU H,LIN B,JIAO X,LUO Y,ZHANG F,et al.Efficacy and safety of intravireal conbercept injections in macular edema secondary to retinal vein occlusion[J].Retina,2017,37(9):1723-1730.
[7] LU Q,LU L,CHEN W,CHEN H,XU X,ZHENG Z.RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy[J].Graefes Arch Clin Exp Ophthalmol,2015,253(5):669-680.
[8] LU Q,LU P,CHEN W,LU L,ZHENG Z.ANGPTL-4 induces diabetic retinal inflammation by activating Profilin-1[J].Exp Eye Res,2018,166:140-150.
[9] PAPADOPOULOS N,MARTIN J,RUAN Q,RAFIQUE A,ROSCONI M P,SHI E,et al.Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap,ranibizumab and bevacizumab[J].Angiogenesis,2012,15(2):171-185.
[10] NIEDERER R L,PERUMAL D,SHERWIN T,MCGHEE C N.Age-related differences in the normal human cornea: a laser scanning in vivo confocal microscopy study[J].Br J Ophthalmol,2007,91(9):1165-1169.
[11] JOYCE N C.Proliferative capacity of the corneal endothelium[J].Prog Retin Eye Res,2003,22:359-389.
[12] FORRESTER J V,DICK A D,MC P,LEE W.The eye: Basic science in practice[M].London: WB Saunders,1996.
[13] PHILIPP W,SPEICHER L,HUMPEL C.Expression of vascular endothelial growth factor and its receptors in inflamed and vascularized human corneas[J].Invest Ophthalmol Vis Sci, 2000,41(9):2514-2522.
[14] CABRAL T,LIMA L H,POLIDO J,DUONG J,OKUDA ,OSHIMA A,et al.Aqueous vascular endothelial growth factor and clinical outcomes correlation after single intravitreal injection of bevacizumab in patients with neovascular age-related macular degeneration[J].Int J Retina Vitreous,2017,3:6.
[15] CELIK N,SCHEUERLE A,AUFFARTH G U,KOPITZ J,DITHMAR S.Intraocular pharmacokinetics of aflibercept and vascular endothelial growth factor-a[J].Invest Ophthalmol Vis Sci,2015,56(10):5574-5578.
[16] WANG X,SAWADA T,KAKINOKI M,MIYAKE T,KAWAMURA H,SAISHIN Y,et al.Aqueous vascular endothelial growth factor and ranibizumab concentrations after monthly and bimonthly intravitreal injections of ranibizumab for age-related macular degeneration[J].Graefes Arch Clin Exp Ophthalmol,2014,252(6):1033-1039.
[17] ARI S,NERGIZ Y,AKSIT I,SAHIN A,CINGU K,CACA I.Evaluation of intracameral injection of ranibizumab and bevacizumab on the corneal endothelium by scanning electron microscopy[J].J Ocul Pharmacol Ther,2015,31(2):100-105.
[18] El CHEHAB H,AGARD E,RUSSO A,BOUJNAH Y,DOT C.Intraocular pressure spikes after aflibercept intravitreal injections[J].Ophthalmologica,2016,236(1):43-47.
[19] KAISER P K,SINGER M,TOLENTINO M,VITTI R,ERICKSON K,SAROJ N,et al.Long-term safety and visual outcome of intravitreal aflibercept in neovascular age-related macular degeneration: VIEW 1 extension study[J].Ophthamol Retina,2017,1(4):304-313.
[20] SCHMIDT-ERFURTH U,KAISER P K,KOROBELNIK J F,BROWN D M,CHONG V,NGUYEN Q D ,et al.Intravitreal aflibercept injection for neovascular age-related macular degeneration: ninety-six-week results of the VIEW studies[J].Ophthalmology,2014,121(1):193-201.
[21] FAUSER S,SCHWABECKER V,MUETHER P S.Suppression of intraocular vascular endothelial growth factor during aflibercept treatment of age-related macular degeneration[J].Am J Ophthalmol,2014,158(3):532-536.
[22] HEIER J S,BROWN D M,CHONG V,KOROBELNIK J F,KAISER P K,NGUYEN Q D,et al.Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration[J].Ophthalmology,2012,119(12):2537-2548.