[1]赵欢欢,穆歌,孙伟,等.早产儿视网膜病变患儿激光光凝术后视功能和屈光状态[J].眼科新进展,2020,40(1):083-85.[doi:10.13389/j.cnki.rao.2020.0021]
 ZHAO Huanhuan,MU Ge,SUN Wei,et al.Observation of visual function and refractive status after laser coagulation for retinopathy of prematurity[J].Recent Advances in Ophthalmology,2020,40(1):083-85.[doi:10.13389/j.cnki.rao.2020.0021]
点击复制

早产儿视网膜病变患儿激光光凝术后视功能和屈光状态/HTML
分享到:

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
40卷
期数:
2020年1期
页码:
083-85
栏目:
应用研究
出版日期:
2020-01-05

文章信息/Info

Title:
Observation of visual function and refractive status after laser coagulation for retinopathy of prematurity
文章编号:
20200121
作者:
赵欢欢穆歌孙伟黄学林
510010 广东省广州市,广东省妇幼保健院眼科
Author(s):
ZHAO HuanhuanMU GeSUN WeiHUANG Xuelin
Department of Ophthalmology,Guangdong Women and Children Hospital,Guangzhou 510010,Guangdong Province,China
Corresponding author:HUANG Xuelin,E-mail:tyhuangxl@163.com
关键词:
早产儿视网膜病变激光光凝术视功能屈光不正眼位
Keywords:
retinopathy of prematuritylaser therapyvisual outcomerefractive errorseye position
分类号:
R774
DOI:
10.13389/j.cnki.rao.2020.0021
文献标志码:
A
摘要:
目的 研究早产儿视网膜病变(retinopathy of prematurity,ROP)患儿激光光凝术后视功能和屈光状态。方法 回顾性队列研究。收集我院行二极管激光光凝术治愈的ROP患儿44 例(88眼),远期随访3 a以上,观察其视力、眼位及屈光状态情况。术后最佳矫正视力(best corrected visual acuity,BCVA)<0.3定义为低视力,术后低视力与出生体质量、孕周、治疗时矫正胎龄、病变区域和激光次数的相关性行Logistic多因素回归分析。结果 44例(88眼)患儿年龄为(4.2±0.8)岁,BCVA≤0.1者2眼,>0.1~0.3者 9眼,>0.3~0.5者14眼,>0.5者63眼。Logistic多因素回归分析显示,术后低视力与出生体质量、孕周、矫正胎龄和激光治疗次数均无相关性(均为P>0.05),与病变区域有关(P=0.049)。近视性屈光不正29眼,近视度数为-0.25~-10.50 D,其中高度近视(SE≥-5.00 D)8眼;合并散光者44眼,散光度-1.00~-5.00 DC,其中高度散光(≥-2.00 DC)20眼;10例患有斜视,1例有眼球震颤。结论 ROP激光术后大部分患儿有较好的视力,高度近视和斜视是视力损伤的主要原因。
Abstract:
Objective To investigate the visual function and refractive status of patients who underwent laser photocoagulation for retinopathy of prematurity (ROP).Methods The retrospective cohort study was carried out on 44 ROP children (88 eyes) who underwent diode laser photocoagulation in our hospital and received long-term follow-up for 3 years.Visual acuity,eye position and refractive status were observed.The best corrected visual acuity (BCVA) <0.3 was defined as low vision.Logistic regression analysis was performed to explore the correlation of postoperative low vision with birth weight,gestational age,corrected gestational age during treatment,lesion area and frequency of laser treatment.Results The mean age of child patient was (4.2±0.8) years.There were 2 eyes with BCVA≤0.1,9 eyes with BCVA >0.1 and ≤0.3,14 eyes with BCVA >0.3 and ≤0.5,and 63 eyes with BCVA>0.5.Logistic regression analysis showed that postoperative low vision had no relation with birth weight,gestational age,corrected gestational age or frequency of laser treatment (all P>0.05),but was related to lesion area (P=0.049).There were 29 eyes with myopic ametropia [with myopia of -0.25 D to -10.50 D],including 8 eyes (9.09%) with high myopia (SE≥-5.00 D);there were 44 eyes with myopia and astigmatism (with astigmatic degree of -1.00 DC to -5.00 DC),including 20 eyes with high astigmatism (with astigmatic degree ≥-2.00 DC).There were 10 child patients with strabismus and 1 child patient with nystagmus.Conclusion The majority of child patients who underwent ROP laser therapy have favorable visual outcomes.High myopia and strabismus are the main causes of visual impairment.

参考文献/References:

[1] HARTNETT M E.Pathophysiology and mechanisms of severe retinopathy of prematurity[J].Ophthalmology,2015,122(1):200-210.
[2] 中华医学会眼科学分会眼底病学组.中国早产儿视网膜病变筛查指南(2014年)[J].中华眼科杂志,2014,50(12):933-935.
The Ocular Fundus Diseases Group of Chinese Ophthalmological Society.The screening guidelines of Chinese retinopathy of prematury(2014)[J].Chin J Ophthalmol,2014,50(12):933-935.
[3] Early Treatment for Retinopathy of Prematurity Cooperative Group.Revised indications for the treatment of retinopathy of prematurity:results of the early treatment for retinopathy of prematurity randomized trial[J].Arch Ophthalmol,2003,121(12):1684-1694.
[4] QUINN G E,DOBSON V,DAVITT B V,WALLACE D K.Progression of myopia and high myopia in the early treatment for retinopathy of prematurity study:findings at 4 to 6 years of age[J].J AAPOS,2013,17(2):124-128.
[5] GOOD W V,HARDY R J,DOBSON V,PALMER E A.On behalf of the Early Treatment for Retinopathy of Prematurity Cooperative Group:Final visual results in the early treatment for retinopathy of prematurity study[J].Arch Ophthalmol,2010,128(6):663-671.
[6] GOOD W V.The Early Treatment for Retinopathy of Prematurity Study:structural findings at age 2 years[J].Br J Ophthalmol,2006,90(11):1378-1382.
[7] CHEN Y H,CHEN S N,LIEN R I,SHIH C P,CHAO A N,CHEN K J,et al.Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity:2-year outcomes[J].Eye (Lond),2014,28(9):1080-1086.
[8] SAVLEEN K,JASPREET S,DEEKSHA K,MANSI S.Refractive and ocular biometric profile of children with a history of laser treatment for retinopathy of prematurity[J].Indian J Ophthalmol,2017,65(9):835-840.
[9] 姚昱欧,尹虹,黎晓新,赵明威,梁建宏.激光光凝治疗对早产儿视网膜病变视野及屈光状态的影响[J].中华眼底病杂志,2017,33(2):148-152.
YAO Y O,YIN H,LI X X,ZHAO M W,LIANG J H.Visual field outcomes and refractive status of retinopathy of prematurity after laser treatment[J].Chin J Ocul Fundus Dis,2017,33(2):148-152.
[10] 冷云霞,张柳,张蒙,吴敏,蔡诚,任国梁,等.早产儿视网膜病变黄斑中心视网膜微血管形态特征:基于光学相干断层扫描血管成像(OCTA)的观察[J].眼科新进展,2018,38(4):357-360.
LENG Y X,ZHANG L,ZHANG M,WU M,CAI C,REN G L,et al.Observation of central macular retinal microvascular network morphology of retinopathy of prematurity by optical coherence tomography angiography[J].Rec Adv Ophthalmol,2018,38(4):357-360.
[11] 孙爽,卢跃兵.早产儿视网膜病变激光术后屈光状态分析[J].实用医药杂志,2018,35(2):134-135.
SUN S,LU Y B.Analysis of refractive status after laser surgery for retinopathy of prematurity[J].Pract J Med Pharm,2018,35(2):134-135.
[12] YANG C S,WANG A G,SHIH Y F,HSU W M.Astigmatism and biometric optic components of diode laser-treated threshold retinopathy of prematurity at 9 years of age[J].Eye,2013,27(3):374-381.
[13] CHEN T C,TSAI T H,SHIH Y F,YEH P T,YANG C H.Long-term evaluation of refractive status and optical components in eyes of children born prematurely[J].Invest Ophthalmol Vis Sci,2010,51(12):6140-6148.
[14] YANG C S,WANG A G,SUNG C S,HSU W M,LEE F L,LEE S M.Long term visual outcomes of laser treated retinopathy of prematurity:a study of refractice status[J].Eye,2010,24(1):14-20.
[15] LU R,HAI D S,XING Z L,XIN H.Refractive Status of Chinese with laser-treated retinopathy of prematurity[J].Optom Vis Sci,2015,92(4):3-9.

相似文献/References:

[1]杜安杰 任兵 高晓唯 付燕 赵旭东 郭继华.氨基胍对氧诱导的视网膜病变小鼠视网膜神经细胞的保护作用[J].眼科新进展,2012,32(12):000.
[2]王宗华 董文丽 陈思扬.早产儿视网膜病变间接检眼镜激光治疗及危险因素分析[J].眼科新进展,2012,32(12):000.
[3]田妮 郭海科 项道满 陈锋 卢艳华.数字化双目间接检眼镜检查系统在早产儿视网膜病变筛查中的应用[J].眼科新进展,2012,32(12):000.
[4]李蓉 王雨生.早期治疗早产儿视网膜病变的多中心临床试验[J].眼科新进展,2012,32(3):000.
[5]彭娟 沙翔垠 杨瑞明 郑瑜.妊娠并发症及围产期感染与早产儿视网膜病变的关系[J].眼科新进展,2012,32(4):000.
[6]王淋淋 唐兰芬 谭建新 阮豫才 方玉兰.曲尼司特抑制早产儿视网膜病变大鼠模型血管新生和纤维化的实验研究[J].眼科新进展,2013,33(10):000.
[7]韩丽英 李兵.IGF-1对大鼠未成熟视网膜新生血管形成的影响[J].眼科新进展,2013,33(10):000.
[8]张国明 李娜 张福燕. 早产儿视网膜病变和足月新生儿眼病筛查指南[J].眼科新进展,2014,34(2):101.
[9]陈芳,宁红珠,曾琼英,等.532nm激光光凝治疗视网膜前出血的临床观察[J].眼科新进展,2014,34(5):480.[doi:10.13389/j.cnki.rao.2014.0132]
 CHEN Fang,NING Hong-Zhu,ZENG Qiong-Ying,et al.Clinical observation of 532 nm laser photocoagulation for pre-retinal hemorrhage[J].Recent Advances in Ophthalmology,2014,34(1):480.[doi:10.13389/j.cnki.rao.2014.0132]
[10]刘梅.Retcam Ⅲ数字视网膜照相机在早产儿视网膜病变筛查中的应用[J].眼科新进展,2014,34(5):483.[doi:10.13389/j.cnki.rao.2014.0133]
 LIU Mei.Application of Retcam Ⅲ digital camera in retinopathy of premature screening[J].Recent Advances in Ophthalmology,2014,34(1):483.[doi:10.13389/j.cnki.rao.2014.0133]
[11]王新茹.玻璃体内注射雷珠单抗联合激光光凝治疗早产儿视网膜病变疗效观察[J].眼科新进展,2018,38(2):172.[doi:10.13389/j.cnki.rao.2018.0039]
 WANG Xin-Ru.Combination of intravitreal injection of ranibizumab and laser photocoagulation for the treatment of retinopathy of prematurity[J].Recent Advances in Ophthalmology,2018,38(1):172.[doi:10.13389/j.cnki.rao.2018.0039]

备注/Memo

备注/Memo:
N/A
更新日期/Last Update: 2020-01-05