[1]黄韵洁,陈晓隆.IgG4相关性眼病研究进展[J].眼科新进展,2019,39(11):1091-1095.[doi:10.13389/j.cnki.rao.2019.0251]
　HUANG Yun-Jie,CHEN Xiao-Long.Research progress of IgG4-related ophthalmic disease[J].Recent Advances in Ophthalmology,2019,39(11):1091-1095.[doi:10.13389/j.cnki.rao.2019.0251]
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年11期
页码:
1091-1095
栏目:
文献综述
出版日期:
2019-11-05

文章信息/Info

Title:
Research progress of IgG4-related ophthalmic disease
作者:
黄韵洁; 陈晓隆
110004　辽宁省沈阳市，中国医科大学附属盛京医院眼科
Author(s):
HUANG Yun-Jie; CHEN Xiao-Long
Department of Ophthalmology,Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning Province,China
关键词:
IgG4相关性眼病; IgG4相关性疾病; 眼眶炎症
Keywords:
IgG4-related ophthalmic diseases; IgG4-related diseases; orbital inflammation
分类号:
R771.3
DOI:
10.13389/j.cnki.rao.2019.0251
文献标志码:
A
摘要:
IgG4相关性疾病是一种近几年才被认识的疾病，病因尚不明确。以同时或逐步出现的一种或多种组织和器官中大量IgG4阳性淋巴浆细胞浸润、席纹状纤维化、闭塞性静脉炎为特征，可伴有血清IgG4水平升高。当累及眼部时称为IgG4相关性眼病。任何眼附属器均可受累，多见于泪腺、眼眶脂肪、眶下神经、眼外肌和眼睑。本文将对近年来IgG4相关性眼病的流行病学特点、病理特点、临床表现、影像特点、诊断和治疗方面的最新进展作一综述。
Abstract:
Immunoglobulin G4 related disease (IgG4-RD) is a recently recognized inflammatory disease，and the etiology is still unknown.One or more organs may be associated simultaneously or subsequently,with the distinctive histopathological characteristic,for example,dense IgG4-positive lymphoplasmacytic infiltration,storiform fibrosis and obliterative phlebitis.When the ophthalmic tissues involved,it is called IgG4-related ophthalmic disease (IgG4-ROD).Although almost any ocular adnexal tissue may be affected,the lacrimal gland,orbital fat,infraorbital nerve,extraocular muscles and eyelid are common.Mikulicz’s disease and most of the orbital idiopathic inflammation belong to IgG4-ROD.This article will review the recent epidemiological characteristics,pathological features,clinical manifestations,imaging features,diagnosis and treatment of I IgG4-ROD.

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更新日期/Last Update: 2019-11-18