[1]田艳明,高雯,闫希东,等.保留眼球的眶周侵袭性恶性肿瘤切除及修复[J].眼科新进展,2019,39(11):1080-1083.[doi:10.13389/j.cnki.rao.2019.0248]
 TIAN Yan-Ming,GAO Wen,YAN Xi-Dong,et al.Resection and repair of periorbital invasive malignant tumors with preserved eyeballs[J].Recent Advances in Ophthalmology,2019,39(11):1080-1083.[doi:10.13389/j.cnki.rao.2019.0248]
点击复制

保留眼球的眶周侵袭性恶性肿瘤切除及修复/HTML
分享到:

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年11期
页码:
1080-1083
栏目:
应用研究
出版日期:
2019-11-05

文章信息/Info

Title:
Resection and repair of periorbital invasive malignant tumors with preserved eyeballs
作者:
田艳明高雯闫希东李鹏杨胜高晓唯
830012 新疆维吾尔族自治区乌鲁木齐市,新疆军区总医院北京路临床部眼科
Author(s):
TIAN Yan-MingGAO WenYAN Xi-DongLI PengYANG ShengGAO Xiao-Wei
Department of Ophthalmology,Xinjiang Military Region General Hospital Beijing Road Clinical Department,Urumqi 830012,Xinjiang Uygur Autonomous Region,China
关键词:
眼眶侵袭性恶性肿瘤放射治疗保留眼球的切除术
Keywords:
orbitinvasive malignant tumorradiotherapyexcision with reserved eyeball
分类号:
R777.5
DOI:
10.13389/j.cnki.rao.2019.0248
文献标志码:
A
摘要:
目的 总结保留眼球及个体化皮瓣修复用于治疗眶周侵袭性恶性肿瘤的手术治疗效果及预后。方法 回顾性分析2007年3月至2016年3月我院收治的14例(14眼)眼睑及眼眶侵袭性恶性肿瘤,手术完整切除肿瘤,残留结膜或皮瓣覆盖眼球,个体化皮瓣修复缺损,对该手术治疗方法的效果进行分析。结果 14眼中眼睑基底细胞癌3眼,鳞状细胞癌4眼,皮脂腺癌6眼,横纹肌肉瘤1眼。14例恶性肿瘤均完整摘除,1例治疗20个月后死亡,1例复发性横纹肌肉瘤放弃继续治疗,1例术后放疗后无光感,皮肤溃疡角膜暴露,其余患者随访2~5 a均无复发,创面愈合良好,皮瓣下眼球运动良好,光感存在。结论 眶周侵袭性恶性肿瘤较为罕见,肿瘤扩大性切除后可以采取保留眼球的手术方式,并根据缺损范围选择合适的皮瓣修复,可以减少创伤,简化手术操作,保留一定外观。血管吻合皮瓣修复应慎重应用于该类侵袭性肿瘤患者中。
Abstract:
Objective To summarize the surgical treatment effects of preserved eyeballs and individualized flap repair for the treatment of orbital eyelid invasive malignant tumors.Methods Retrospective analysis of 14 patients (14 eyes) with invasive malignant tumors of eyelid and orbit treated in our hospital from March 2007 to March 2016 after complete surgical resection of the tumor,residual conjunctiva,or flap covering the eyeball and individual flap repair was performed.Results In the 14 eyes,there were 3 eyes with basal cell carcinoma of eyelid,4 eyes with squamous cell carcinoma,6 eyes with sebaceous adenocarcinoma and 1 eye with rhabdomyosarcoma.All 14 patients of malignant tumors were completely removed,but one patient died after 20 months of treatment.One patient with recurrent rhabdomyosarcoma declined further treatment.One patient had no light perception after postoperative radiotherapy and developed skin ulcers and corneal leakage.The remaining patients were followed up for 2 to 5 years without recurrence;the wounds healed well,the eyeballs under the flaps had good movement,and light perception was present.Conclusion Invasive orbital and eyelid tumors are rare.The eyeballs can often be preserved after complete tumor resection.Appropriate flap selection according to the defect range can reduce trauma,simplify the operation and preserve the appearance.However,flaps with vascular anastomoses should be carefully applied to such patients.

参考文献/References:

[1] KNACKSTEDT T,SAMIE F H.Sebaceous carcinoma:a review of the scientific literature[J].Curr Treat Options Oncol,2017,18(8):47.
[2] BONAVOLONT P,ORABONA G,ABBATE V,IACONETTA G,BONAVOLONT G,CALIFANO L.Treatment of metastatic eyelid carcinoma[J].J Craniofac Surg,2017,28(8):722-725.
[3] XIAO L H.Orbit surgery and illustration [M].Henan:Henan Science and Technology Press,2000:88.
肖利华.眼眶手术学及图解[M].河南:河南科学技术出版社,2000:88.
[4] WU Z Y.Modern eye tumor orbit disease[M].Beijing:People’s Military Medical Press,2002:83.
吴中耀.现代眼肿瘤眼眶病学[M].北京:人民军医出版社,2002:83.
[5] SHI Y Y,JIA R B,FAN X Q.Ocular basal cell carcinoma:a brief literature review of clinical diagnosis and treatment[J].Onco Targets Ther,2017,10:2483-2489.
[6] MICHELLE T,ALBERT W,EDWIN F,SHYAMALA H,DINESH S.Management of periorbital basal cell carcinoma with orbital invasion[J].Future Oncol,2015,11(22):3003-3010.
[7] NEMET A Y,MARTIN P,BENGER R,KOURT G,SHARMA V,GHABRIAL R,et al.Orbital exenteration:a 15-year study of 38 cases[J].Ophthalmic Plast Reconstr Surg,2007,23(6):468-472.
[8] KAINES A,DAVIS G,SELVA D,LEIBOVITCH I,DODD T,MALHOTRA R.Conjunctival squamous cell carcinoma with perineural invasion resulting in death[J].Ophthalmic Surg Lasers Imaging,2005,36(3):249-251.
[9] IULIANO A,STRIANESE D,UCCELLO G,DIPLOMATICO A,TEBALDI S,BONAVOLONTA G.Risk factors for orbital exenteration inperiocular basal cell carcinoma[J].Am J Ophthalmol,153(2),238-241.
[10] MURCHISON A P,WALRATH J D,WASHINGTON C V.Non-surgical treatments of primary,non-melanoma eyelid malignancies:a review[J].Clin Exp Optom,2011,39(1):65-83.
[11] BARNES E A,BREEN D,CULLETON S,ZHANG L,KAMRA J,TSAO M,et al.Palliative radiotherapy for non-melanomaskin cancer[J].Clin Oncol,2010,22(10):844-849.
[12] AI S M,YANG H S,WU Z Y.Efficacy and follow-up analysis of 126 cases of orbital basal cell carcinoma after microscopic controlled resection[J].Chin J Prac Ophthalmol,2003,21(1):62-63.
艾思明,杨华胜,吴中耀.126例眼睑基底细胞癌显微控制性切除术后疗效及其随访分析[J].中国实用眼科杂志,2003,21(1):62-63.
[13] KHTIBAR I Z,EL BELHADJI M,BENHMIDOUNE L,BERRADA S,RQIBATE S,AMRAOUI A.Squamous cell carcinoma of the eyelids.Review of 7 years of experience of the adult ophthalmology service of the Casablanca university medical center[J].J Franc Ophthalmol,2015,38(2):134-140.

相似文献/References:

[1]王娟,庞润晖,刘兆川,等.肌圆锥内注射透明质酸对幼兔眼眶发育的影响[J].眼科新进展,2016,36(4):331.[doi:10.13389/j.cnki.rao.2016.0089]
 WANG Juan,PANG Run-Hui,LIU Zhao-Chuan,et al.Effects of injecting hyaluronic acid into muscle cone on orbital development of immature rabbits[J].Recent Advances in Ophthalmology,2016,36(11):331.[doi:10.13389/j.cnki.rao.2016.0089]
[2]朱利民,何彦津,林婷婷.眼眶急性炎症的病例分析及鉴别诊断[J].眼科新进展,2019,39(7):649.[doi:10.13389/j.cnki.rao.2019.0149]
 ZHU Li-Min,HE Yan-Jin,LIN Ting-Ting.Clinical analysis and antidiastole of eye disorders which manifest as acute orbital inflammation[J].Recent Advances in Ophthalmology,2019,39(11):649.[doi:10.13389/j.cnki.rao.2019.0149]

更新日期/Last Update: 2019-11-18