[1]华英彬,吴培培,石德鹏,等.不同类型脉络膜新生血管光学相干断层扫描血管成像（OCTA）的图像特征[J].眼科新进展,2019,39(11):1048-1051.[doi:10.13389/j.cnki.rao.2019.0240]
　HUA Ying-Bin,WU Pei-Pei,SHI De-Peng,et al.Image characteristics of different types of choroidal neovascularization on optical coherence tomography angiography[J].Recent Advances in Ophthalmology,2019,39(11):1048-1051.[doi:10.13389/j.cnki.rao.2019.0240]
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不同类型脉络膜新生血管光学相干断层扫描血管成像（OCTA）的图像特征/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年11期
页码:
1048-1051
栏目:
应用研究
出版日期:
2019-11-05

文章信息/Info

Title:
Image characteristics of different types of choroidal neovascularization on optical coherence tomography angiography
作者:
华英彬; 吴培培; 石德鹏; 徐海峰
261053　山东省潍坊市，潍坊医学院，山东省眼科研究所，青岛眼科医院（华英彬）；266071　山东省青岛市，山东省眼科研究所，青岛眼科医院（吴培培，石德鹏，徐海峰）
Author(s):
HUA Ying-Bin; WU Pei-Pei; SHI De-Peng; XU Hai-Feng
Weifang Medical University，Shandong Eye Institute，Qingdao Eye Hospital （HUA Ying-Bin），Weifang 261053，Shandong Province，China；Shandong Eye Institute，Qingdao Eye Hospital （WU Pei-Pei，SHI De-Peng，XU Hai-Feng），Qingdao 266071，Shandong Province，China
关键词:
脉络膜新生血管; 光学相干断层扫描血管成像; 新生血管面积
Keywords:
choroidal neovascularization; optical coherence tomography angiography; neovascularization area
分类号:
R773.4
DOI:
10.13389/j.cnki.rao.2019.0240
文献标志码:
A
摘要:
目的　观察不同类型脉络膜新生血管（choroidal neovascularization，CNV）光学相干断层扫描血管成像（optical coherence tomography angiography，OCTA）的图像特征，探讨OCTA在CNV诊治中的作用。方法　回顾性分析经荧光素眼底血管造影联合吲哚菁绿血管造影确诊的未经治疗的黄斑部Ⅰ型及Ⅱ型CNV患者的OCTA图像，观察不同类型CNV的OCTA图像特点，采用Image J图像分析软件测量不同类型CNV在OCTA图像上的异常血管面积。结果　31例31眼患者符合纳入标准，其中男19例、女12例；Ⅰ型CNV 17眼，血管构型较疏松，形状不规则，异常血管长、直，面积较大，为（1.565±1.400）mm2；Ⅱ型CNV 14眼，血管分支浓密，多呈圆形或类圆形，异常血管相对粗短，呈绒球状构型，面积较小，为（0.418±0.374）mm2。Ⅰ型CNV和Ⅱ型CNV异常血管面积比较，差异有统计学意义（P=0.008）。结论　不同类型的CNV有不同的OCTA图像特征，这些特征与荧光素眼底血管造影和（或）吲哚菁绿血管造影所显示的特征一致。OCTA可作为CNV诊断、分型的重要工具。
Abstract:
Objective　To observe the image characteristics of optical coherence tomography angiography (OCTA) in different types of choroidal neovascularization (CNV),and to explore the roles of OCTA in the diagnosis and treatment of CNV.Methods　The OCTA images of untreated patients with type Ⅰ and type Ⅱ CNV in macular region confirmed by fluorescein fundus angiography and indocyanine green angiography were retrospectively analyzed.The characteristics of OCTA images of different types of CNV were observed.The abnormal blood vessel area of different types of CNV on OCTA images was measured by Image J.Results　Totally 31 eyes of 31 patients met the inclusion criteria,including 19 males and 12 females;17 eyes of type I CNV had looser vascular configuration,irregular shape,long and straight abnormal blood vessels with a larger area of (1.565±1.400)mm2;14 eyes of type Ⅱ CNV had dense vascular branches,mostly round or quasi-circular,relatively thick and short abnormal blood vessels with a smaller area of (0.418±0.374)mm2.There was a significant difference in the area of abnormal vessels between type I CNV and type Ⅱ CNV (P=0.008).Conclusion　Different types of CNV have different characteristics of OCTA images,which are consistent with the characteristics of fluorescein angiography and / or indocyanine green angiography,so OCTA can be used as an important tool for diagnosing and typing CNV.

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备注/Memo

备注/Memo:
山东省重点研发计划（省攻关公益类）项目（编号：2017GSF18141）；山东省优秀中青年科学家科研奖励基金资助（编号：BS2014SF003）
更新日期/Last Update: 2019-11-18