[1]朱丽娟,朱豫,冯沛贝,等.泪囊实性肿物的临床病理分析[J].眼科新进展,2019,39(4):363-365.[doi:10.13389/j.cnki.rao.2019.0082]
　ZHU Li-Juan,ZHU Yu,FENG Pei-Bei,et al.Clinicopathological analysis of tumors of the lacrimal sac[J].Recent Advances in Ophthalmology,2019,39(4):363-365.[doi:10.13389/j.cnki.rao.2019.0082]
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泪囊实性肿物的临床病理分析/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年4期
页码:
363-365
栏目:
应用研究
出版日期:
2019-04-05

文章信息/Info

Title:
Clinicopathological analysis of tumors of the lacrimal sac
作者:
朱丽娟; 朱豫; 冯沛贝; 郝尚臣
450052　河南省郑州市，郑州大学第一附属医院眼科（朱丽娟，朱豫，郝尚臣）；450000　河南省郑州市，郑州大学附属郑州市中心医院肿瘤科（冯沛贝）
Author(s):
ZHU Li-Juan;  ZHU Yu;  FENG Pei-Bei; HAO Shang-Chen
Department of Ophthalmology，the First Affiliated Hospital of Zhengzhou University（ZHU Li-Juan，ZHU Yu，HAO Shang-Chen），Zhengzhou 450052，Henan Province，China；Department of Oncology，Zhengzhou Central Hospital Affiliated to Zhengzhou University（FENG Pei-Bei），Zhengzhou 450000，Henan Province，China
关键词:
泪囊; 肿物; 病理; 预后
Keywords:
lacrimal sac; tumor; pathology; prognosis
分类号:
R777.2
DOI:
10.13389/j.cnki.rao.2019.0082
文献标志码:
A
摘要:
目的　探讨泪囊实性肿物的临床病理特征。方法　回顾性分析2007年至2017年于我院诊治并经组织病理检查确诊的20例泪囊实性肿物患者的临床资料。结果　20例泪囊实性肿物中，男11例，女9例，发病年龄1~81岁，平均53岁。20例均为单眼发病，均可见为泪囊区肿胀隆起；伴溢泪者15例，同时伴脓性分泌物者4例，血性分泌物者3例；泪囊区及眶周红、肿、疼痛2例。病理结果显示：良性肿物8例，其中肉芽肿3例，炎性肌纤维母细胞瘤3例，鳞状上皮乳头状瘤1例，错构瘤1例；恶性肿瘤12例，其中淋巴瘤6例，恶性黑色素瘤3例，胚胎型横纹肌肉瘤1例，鳞癌2例。预后：4例患者死亡，其中2例为恶性黑色素瘤患者，2例为弥漫性大B细胞淋巴瘤患者；1例鳞癌患者5 a后出现口腔部鳞癌生长；余15例患者未见肿物复发及转移。结论　泪囊肿物临床表现多样，易误诊、漏诊，需引起眼科医师重视，对可疑患者进行相关辅助检查，确诊后根据病理类型及肿物分期行手术、放疗、化疗等个体化综合治疗。
Abstract:
Objective　To investigate the clinicopathological features of lacrimal sac tumors.Methods　We retrospectively analyzed clinical data of 20 patients of lacrimal sac tumors confirmed by pathological examination in our hospital from 2007 to 2017.Results　Of the 20 patients of lacrimal sac tumors，11 were males and 9 were females，with a mean age of 53 years （range，1-81 years）.All 20 patients were found to be unilateral and presented with swelling and lump in the lacrimal sac region，accompanied by epiphora in 15 patients，pyoid tears in 4 patients，bloody tears in 3 patients.There were 2 patients had redness，swelling and pain in dacryocyst region.Pathological types were as follows：8 patients of benign tumor，including 3 patients of granuloma，3 patients of inflammatory myofibroblastoma，1 patient of squamous epithelial papilloma and 1 patient of hamartoma.There were 12 patients of malignant tumor，including 6 patients of lymphoma，3 patients of malignant melanoma，1 patient of embryonic rhabdomyosarcoma and 2 patients of squamous cell carcinoma.Prognosis：four patients died，including 2 patients of malignant melanoma and 2 patients of diffuse large B cell tumor.One patient of squamous cell carcinoma developed oral squamous cell carcinoma after 5 years.No recurrence or metastasis was seen in the remaining patients.Conclusion　The clinical manifestations of lacrimal sac tumor are various and easy to be misdiagnosed and missed.Ophthalmologists need to pay attention to the suspicious patients and perform related examinations.Individualized comprehensive therapy such as surgery，radiotherapy，chemotherapy，etc should be adopted based on pathological types and stage of lacrimal sac tumor.

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更新日期/Last Update: 2019-04-15