[1]陈莲,王延辉,杨帆,等.视网膜中央静脉阻塞与阻塞性睡眠呼吸暂停综合征的相关性[J].眼科新进展,2019,39(2):183-186.[doi:10.13389/j.cnki.rao.2019.0042]
　CHEN Lian,WANG Yan-Hui,YANG Fan,et al.Relationship between central retinal vein occlusion and obstructive sleep apnea syndrome[J].Recent Advances in Ophthalmology,2019,39(2):183-186.[doi:10.13389/j.cnki.rao.2019.0042]
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视网膜中央静脉阻塞与阻塞性睡眠呼吸暂停综合征的相关性/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年2期
页码:
183-186
栏目:
应用研究
出版日期:
2019-02-05

文章信息/Info

Title:
Relationship between central retinal vein occlusion and obstructive sleep apnea syndrome
作者:
陈莲; 王延辉; 杨帆; 何珂; 李晓清; 姜钊; 李璐希; 张鹏
710018　陕西省西安市，西安市第三医院眼科，西北大学附属医院眼科（陈莲，何珂，李晓清，姜钊，李璐希，张鹏）；710018　陕西省西安市，西安市第三医院耳鼻喉科，西北大学附属医院耳鼻喉科（王延辉，杨帆）
Author(s):
CHEN Lian; WANG Yan-Hui; YANG Fan; HE Ke; LI Xiao-Qing; JIANG Zhao; LI Lu-Xi; ZHANG Peng
Department of Ophthalmology,Xi’an No.3 Hospital,the Affiliated Hospital of Northwest University (CHEN Lian,HE Ke,LI Xiao-Qing,JIANG Zhao,LI Lu-Xi,ZHANG Peng),Xi’an 710018,Shaanxi Province,China;Department of Otorhinolaryngology,Xi’an No.3 Hospital,the Affiliated Hospital of Northwest University(WANG Yan-Hui,YANG Fan),Xi’an 710018,Shaanxi Province,China
关键词:
视网膜中央静脉阻塞; 检查; 睡眠呼吸暂停综合征
Keywords:
central retinal vein occlusion; examination; obstructive sleep apnea
分类号:
R774
DOI:
10.13389/j.cnki.rao.2019.0042
文献标志码:
A
摘要:
目的　探讨视网膜中央静脉阻塞(central retinal vein occlusion,CRVO)与阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAS)的相关性。方法　选择CRVO组患者及非CRVO患者（对照组）各24例进行研究。采用多导睡眠呼吸记录仪在夜间对CRVO患者及对照组的呼吸暂停低通气指数(apnea-hypopnea index，AHI)、夜间平均最小氧饱和度等指标进行监测。根据AHI对OSAS进行诊断。对两组的OSAS发生率、AHI、夜间平均最小氧饱和度、年龄、体质量指数(body mass index,BMI)等进行比较。结果　CRVO组BMI（25.49±4.17）kg·m-2和AHI（18.89±14.54）与对照组［BMI：(22.57±5.25)kg·m-2、AHI：8.25±6.98］相比均明显升高，而CRVO组夜间平均最小氧饱和度（80.04±11.63）%与对照组（89.14±7.22）%相比明显降低，差异均有统计学意义（均为P<0.05）。其中，CRVO组OSAS患病率为75.00%，显著高于对照组（37.50%），差异有统计学意义（P<0.05）。OSAS组［年龄（59.67±9.32）岁、BMI(27.59±5.19)kg·m-2和AHI (21.16±12.08)］与非OSAS组［年龄（53.31±7.04）岁、BMI（22.15±4.94）kg·m-2、AHI（3.76±1.13）］相比均明显升高，而患者夜间平均最小氧饱和度（81.42±6.61）%与非OSAS组（87.08±5.77）%相比明显降低，差异均有统计学意义（均为P<0.05）。13例非缺血型CRVO患者中有OSAS 11例（84.62%），11例缺血型CRVO患者中有OSAS 7例（63.64%），OSAS在非缺血型及缺血型CRVO患者中的患病率差异无统计学意义（P>0.05）。结论　CRVO患者中OSAS的患病率较高，提示OSAS在CRVO的发病进程中起重要作用或者是CRVO发病的使动因素。
Abstract:
Objective　To determine the relationship between central retinal vein occlusion (CRVO) and obstructive sleep apnea syndrome (OSAS).Methods　The participants of this retrospective study included 24 consecutive patients with CRVO and 24 age- and sex-matched controls.All participants underwent full-night respiratory polysomnography for monitoring apnea-hypopnea index (AHI),minimal oxygen saturation and body mass index (BMI).Statistical comparisons were performed between the incidence of OSAS,mean AHI,minimum oxygen saturation,age,BMI in both groups.Results　When compared with that in control group (BMI:22.57±5.25,AHI:8.25±6.98),both the BMI (25.49±4.17)kg·m-2 and AHI (18.89±14.54) were significantly increased in the CRVO group,while the average minimum oxygen saturation in CRVO group decreased significantly than that in control group (89.14±7.22%) (all P<0.05).The incidence of OSAS in CRVO group was 75.00%,which was significantly higher than that in the control group (37.50%) (P<0.05).The age ［(59.67±9.32)years old］,BMI (27.59±5.19)kg·m-2 and AHI (21.16±12.08) of OSAS group were significantly higher than those of non-OSAS group ［age:(53.31±7.04)years,BMI:(22.15±4.94)kg·m-2,AHI:3.76±1.13］,while the average minimum oxygen saturation (81.42±6.61)% was significantly lower than that of non-OSAS group (87.08±5.77)%.The differences were statistically significant (all P<0.05).There were 11 patients of OSAS (84.62%) in 13 patients with non-ischemic CRVO and 7 patients of OSAS (63.64%) in 11 patients with ischemic CRVO and there was no significant difference in the incidence of OSAS between non-ischemic and ischemic CRVO (P>0.05).Conclusion　The CRVO patients have a high prevalence of OSAS,indicating that OSAS might be an important role or a triggering factor in the pathogenesis of CRVO.

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更新日期/Last Update: 2019-02-18