[1]高鸽,姜媛,孙红芬,等.超广角荧光素眼底血管造影在视网膜分支静脉阻塞诊治中的应用[J].眼科新进展,2018,38(7):677-679.[doi:10.13389/j.cnki.rao.2018.0159]
　GAO Ge,JIANG Yuan,SUN Hong-Fen,et al.Ultrawide-angle fluorescence imaging in the diagnosis and treatment of branch retinal vein occlusion[J].Recent Advances in Ophthalmology,2018,38(7):677-679.[doi:10.13389/j.cnki.rao.2018.0159]
点击复制

超广角荧光素眼底血管造影在视网膜分支静脉阻塞诊治中的应用/HTML
分享到：

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
38卷
期数:
2018年7期
页码:
677-679
栏目:
应用研究
出版日期:
2018-07-05

文章信息/Info

Title:
Ultrawide-angle fluorescence imaging in the diagnosis and treatment of branch retinal vein occlusion
作者:
高鸽; 姜媛; 孙红芬; 薛晓辉; 郑波
710004　陕西省西安市，西安市第四医院眼科
Author(s):
GAO Ge; JIANG Yuan; SUN Hong-Fen; XUE Xiao-Hui; ZHENG Bo
Ophthalmology，the Fourth Hospital of Xi’an，Xi’an 710004，Shaanxi Province，China
关键词:
超广角荧光素眼底血管造影; 传统荧光素眼底血管造影; 视网膜静脉阻塞
Keywords:
ultra-wide angle fluorescein fundus angiography; traditional fluorescein fundus angiography; retinal vein occlusion
分类号:
R774.1
DOI:
10.13389/j.cnki.rao.2018.0159
文献标志码:
A
摘要:
目的　评价超广角荧光素眼底血管造影（fundus fluorescein angiography，FFA）在视网膜分支静脉阻塞诊断、治疗中的指导价值。方法　回顾分析40例（41眼）视网膜分支静脉阻塞确诊患者的传统FFA和超广角FFA资料。所有患者造影检查的早中期均行传统FFA，晚期均行欧堡超广角FFA。分析比较2种检查的视网膜可视范围、视网膜无灌注区面积、视网膜所需激光面积。结果　与传统FFA图像比较，超广角FFA检查图像所显示的视网膜可视面积以及视网膜无灌注区面积、所需激光面积分别是前者的2.03倍、1.57倍、1.96倍（均为P<0.01）。未行激光治疗的27眼中22眼有无灌注区，其中同时合并黄斑水肿者15眼，这15眼中无灌注区在赤道部以前者14眼；已行激光治疗的14眼中9眼存在黄斑水肿的表现，9眼中7眼合并无灌注区，其中6眼的无灌注区在赤道部以前。结论　超广角FFA使可观测病变检查范围扩大到远周边，对视网膜分支静脉阻塞的诊断和治疗提供更多帮助。
Abstract:
Objective　To evaluate the guiding value of ultrawide-angle fluorescein fundus angiography(FFA) in the diagnosis and treatment of branch retinal vein occlusion.Methods　Retrospective analysis of 40 cases （41 eyes） of traditional FFA and ultra wide angle FFA data of patients with branch retinal vein occlusion was conducted.All patients underwent conventional FFA in the early and middle stages of angiography，and all of them underwent ultra-wide angle FFA in late stage.The visual range of the retina，the area without perfusion and the laser area of the retina were compared.Results　Compared with the traditional FFA image，ultra-wide angle FFA examination showed the visual area of retina，and the area of retinal instillation，and the required laser area were 2.03，1.57 and 1.96 times of the former one （all P<0.01）.Of the 27 eyes without laser treatment，22 had no perfusion area，with 15 of them being macular edema as well.In those 15 eyes，the non-perfusion area of 14 ones occurred in the peripheral retina.Of 14 eyes treated with laser therapy，9 eyes showed the presence of macular edema and the non-perfusion area in 7 eyes occurred in the peripheral retina.Conclusion　Ultra-wide angle FFA expands the scope of examination to the far periphery，and provides more help for the diagnosis and treatment of branch retinal vein occlusion.

参考文献/References:

［1］　RABENA M D，PIERAMICI D J，CASTELLARIN A A，NASIR M A，AVERY R L.Intravitreal bevacizumab （Avastin） in the treatment of macular edema secondary to branch retinal vein occlusion［J］.Retina，2007，27（4）：419-425.
［2］　TSUI L，KAINES A，HAVUNJIAN M A，HUBSCHMAN S，HEILWEIL G，PRASAD P S，et al.Ischemic index and neovascularization in central retinal vein occlusion［J］.Retina，2011，31（1）：105-110.
［3］　ZHOU J Q.WEI W B.Optos200Tx scannjng laser ophthalmoscope for wide-field fluorescein angiography and its clinical Application［J］.Int Rev Ophthalmol，2015，39（2）：103-106.
周金琼，魏文斌.Optos 200Tx广角眼底血管造影及其临床应用［J］.国际眼科纵览，2015，39（2）：103-106.
［4］　MCINTOSH R L，MOHAMED Q，SAW S M，WONG T Y.Interventions for Branch retinal vein occlusion：an evidence-based systematic review［J］.Ophthalmology，2007，114（5）：835-854.
［5］　ZHANG P，SHANG Q L，MA J X，YE C X，HAO Y H，YAO Y M.Risk factors associated with neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy［J］.Chin J Ocul Fundus Dis，2017，33（3）：271-274.
张鹏，尚庆丽，马景学，叶存喜，郝玉华，姚一民.增生型糖尿病视网膜病变患者玻璃体切割手术后新生血管性青光眼危险因素分析［J］.中华眼底病杂志，2017，33（3）：271-274.
［6］　KAUR C，FOULDS W S，LING E A.Blood-retinal barrier in hypoxic ischaemic conditions：basic concepts，clinical features and management［J］.Prog Retin Eye Res，2008，27（6）：622-647.
［7］　SILVA P S，CAVALLERANO J D，SUN J K，NOBLE J，AIELLO L M，AIELLO L P.Nonmydriatic ultrawide field retinal imaging compared with dilated standard 7-field 35-mm and retinal specialist examination for evaluation of diabetic retinopathy［J］.Am J Ophthalmol，2012，154（3）：549-559.
［8］　FRIBERQ T R，GUPTA A，YU J，HUANG L，SUNER L，PULIAFITO C A，et al.Ultrawide angle luorescein angiographic Imaging：a comparison to conventional digital acquisition systems［J］.Ophthamic Surg Lasers Imaging，2008，39（4）：304-311.
［9］　OLIVER S C，SCHWARTZ S D.Peripheral vessel leakage（PVL）：a new angiographic finding in diabetic retinophthy identified with ultra wide-field fluorescein angiography［J］.Semin Ophthalmol，2010，（1-2）：27-33.
［10］　PRADEEP P S，PRASAD M D，SCOTT C，OlIVER M D，ROBERT E，COFFEE M D，et al.Ultra wide-field angiographic characteristics of branch retinal and hemicentral retinal vein occlusion［J］.Ophthalmology，2010，117（4）：780-784.
［11］　TIAN M，WANG K.Applications of ultra-wide-field fluorescein angiography in the diagnosis and treatment retinal diseases［J］.Chin J Ocul Fundus Dis，2017，33（1）：90-92.
田梦，王康.超广角荧光素眼底血管造影在视网膜疾病诊断和治疗中的研究现状［J］.中华眼底病杂志，2017，33（1）：90-92.
［12］　RICHARD F，SPAIDE M D.Prospective study of peripheral panretinal photocoagulation of areas of nonperfusion in central retinal vein occlusion［J］.Retina，2013，33（1）：56-62.

更新日期/Last Update: 2018-07-12