[1]郭芳,魏瑞华,吴绵绵,等.近视动物模型及发病机制的研究进展[J].眼科新进展,2018,38(5):490-496.[doi:10.13389/j.cnki.rao.2018.0115]
 GUO Fang,WEI Rui-Hua,WU Mian-Mian,et al.Research advances in the animal models and pathogenic mechanisms of myopia[J].Recent Advances in Ophthalmology,2018,38(5):490-496.[doi:10.13389/j.cnki.rao.2018.0115]
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近视动物模型及发病机制的研究进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
38卷
期数:
2018年5期
页码:
490-496
栏目:
文献综述
出版日期:
2018-05-05

文章信息/Info

Title:
Research advances in the animal models and pathogenic mechanisms of myopia
作者:
郭芳魏瑞华吴绵绵孙笑笑张琰
300384 天津市,天津医科大学眼科医院,天津医科大学眼科研究所,天津医科大学眼视光学院
Author(s):
GUO FangWEI Rui-HuaWU Mian-MianSUN Xiao-XiaoZHANG Yan
Tianjin Medical University Eye Hospital,Tianjin Medical University Eye Institute,College of Optometry and Ophthalmology,Tianjin Medical University,Tianjin 300384,China
关键词:
近视动物模型发病机制形觉剥夺性近视光学离焦性近视
Keywords:
myopiaanimal modelspathogenesisform-deprivated myopialens-induced myopia
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2018.0115
文献标志码:
A
摘要:
近视已成为一种常见病,影响公众生活质量,危害公众健康,探索其发病机制有助于疾病的预防和治疗。然而目前近视的发病机制尚不明确,仍然是研究的重点和难点。自20世纪70年代发展至今,近视动物模型的相关研究已有突破性的进展,从分子机制、信号通路、药物干预等方面为近视发病机制的研究提供了证据和思路。本文就常见近视动物模型及发病机制的研究进展进行综述。
Abstract:
Myopia has become a common disease all over the world,affecting the public quality of life and endangering public health.Exploring the pathogenesis is helpful for the prevention and treatment for myopia.However,the pathogenesis of myopia is still not clear,which makes it a hotspot and nodus.From the 1970s,the research on myopic animal models has made great breakthrough.It has provided valuable evidences and hint for mechanism research from the perspective of molecular mechanism,signal pathway,drug intervention,etc.In this paper,the research progess on common myopic animal models and pathogenesis will be reviewed.

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备注/Memo

备注/Memo:
国家级和市级大学生创新创业训练计划项目(编号:201710062036)
更新日期/Last Update: 2018-05-09