[1]李上,臧云晓,张薇,等.穿透性角膜移植联合白内障摘出及人工晶状体植入术疗效观察[J].眼科新进展,2018,38(4):344-347.[doi:10.13389/j.cnki.rao.2018.0080]
 LI Shang,ZANG Yun-Xiao,ZHANG Wei,et al.Clinical observation of a triple procedure of stimultaneous penetrating keratoplasty combined with extracapsular cataract extraction and intraocular lens implantation[J].Recent Advances in Ophthalmology,2018,38(4):344-347.[doi:10.13389/j.cnki.rao.2018.0080]
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穿透性角膜移植联合白内障摘出及人工晶状体植入术疗效观察/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
38卷
期数:
2018年4期
页码:
344-347
栏目:
应用研究
出版日期:
2018-04-05

文章信息/Info

Title:
Clinical observation of a triple procedure of stimultaneous penetrating keratoplasty combined with extracapsular cataract extraction and intraocular lens implantation
作者:
李上臧云晓张薇董宏伟郭纯刚卢红双潘志强接英
100069 北京市,首都医科大学附属北京佑安医院眼科(李上,张薇,董宏伟,郭纯刚);100730 北京市,首都医科大学附属北京同仁医院北京同仁眼科中心(臧云晓,卢红双,潘志强,接英)
Author(s):
LI ShangZANG Yun-XiaoZHANG WeiDONG Hong-WeiGUO Chun-GangLU Hong-ShuangPAN Zhi-QiangJIE Ying
Department of Ophthalmology,Beijing Youan Hospital,Capital Medical University (LI Shang,ZHANG Wei,DONG Hong-Wei,GUO Chun-Gang),Beijing 100069,China;Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University (ZANG Yun-Xiao,LU Hong-Shuang,PAN Zhi-Qiang,JIE Ying),Beijing 100730,China
关键词:
穿透性角膜移植术白内障囊外摘除术三联手术
Keywords:
penetrating keratoplastyextracapsular cataract extractiontriple procedure
分类号:
R779.6
DOI:
10.13389/j.cnki.rao.2018.0080
文献标志码:
A
摘要:
目的 评价同时行穿透性角膜移植、白内障囊外摘出联合人工晶状体植入术(简称三联手术)患者的手术效果,探讨三联手术术后角膜屈光力与术前晶状体度数的选择。方法 回顾性分析2016年4月至10月在北京佑安医院行三联手术的15例患者资料,观察患者术后1 a的最佳矫正视力(best corrected visual acuity,BCVA)、眼压、角膜屈光度、眼轴长度、并发症及角膜内皮细胞数以及植片存活情况。结果 所有患者术后1 a角膜植片均保持透明,角膜内皮细胞数为(1974.20±472.82)个·mm-2。术后BCVA为(0.80±0.27)LogMAR,与术前(2.63±0.62)LogMAR相比,有显著性提高(t=13.042,P<0.001)。术后眼压为(14.53±3.04)mmHg(1 kPa=7.5 mmHg),与术前眼压(15.27±2.37)mmHg相比,差异无统计学意义(t=0.685,P=0.505)。术后眼轴长度为(23.62±2.12)mm,与术前(23.69±2.01)mm相比,差异无统计学意义(t=-0.138,P=0.893)。术后角膜屈光度为(42.56±5.48)D,与术前对侧眼(45.01±1.66)D相比,差异无统计学意义(t=1.202,P=0.260)。术前目标屈光度为(0.58±0.25)D,术后等效球镜度为(0.40±4.65)D。结论 三联手术对于治疗伴有白内障的角膜疾病是一种安全有效的手术方式,术前选择预留偏正视的晶状体度数可能获得满意的术后视力,但术后不可预知的角膜曲率改变仍会对屈光状态造成影响。
Abstract:
Objective To evaluate the operative outcomes of a triple procedure including simultaneous penetration keratoplasty (PKP),extracapsular cataract extraction (ECCE) and intraocular lens (IOL) implantation,and to investigate the relationship between postoperative corneal refractive power and preoperative lens diopter.Methods This retrospective analysis study involved 15 patients who had undergone a triple procedure surgery in Beijing You’an hospital from April to October 2016.Outcomes including the best corrected visual acuity (BCVA),intraocular pressure (IOP),corneal refractive power,axial length,postoperative complications,corneal endothelial cell counts and the survival of corneal graft were determined one year after surgery.Results All corneal grafts were transparent and corneal endothelium were (1974.20±472.82)cell·mm-2.The mean postoperative LogMAR visual acuity (0.80±0.27) had a significant improvement compared with the mean preoperative LogMAR visual acuity (2.63±0.62) (t=13.042,P<0.001).There were no statistically significant differences in preoperative IOP (15.27±2.37)mmHg (1 kPa=7.5 mmHg) and postoperative data (14.53±3.04)mmHg (t=0.685,P=0.505),preoperative axial length (23.69±2.01) mm and postoperative data (23.62±2.12)mm (t=-0.138,P=0.893) and preoperative keratometry (45.01±1.66) D of the control eye and postoperative data (42.56±5.48) D (t=1.202,P=0.260).The postoperative spherical equivalent refractive was (0.40±4.65) D,and the target refraction was (0.58±0.25)D.Conclusion The triple procedures are safe and effective for the treatment of patients with coexisting corneal pathologies and cataracts.Selection of emmetropia lens diopter may result in the satisfactory postoperative visual acuity.However,unpredictable postoperative corneal curvature changes will still affect the final refractive state.

参考文献/References:

[1] TAYLOR DM.Keratoplasty and intraocular lenses[J].Ophthalmic Surg,1976,7(1):31-42.
[2] ARDJOMAND N,FELLNER P,MORAY M,WOHLFART C,MCALISTER JC,EL-SHABRAWI Y.Lamellar corneal dissection for visualization of the anterior chamber before triple procedure[J].Eye (Lond),2007,21(9):1151-1154.
[3] YANG S,WANG B,ZHANG Y,ZHAI H,WANG J,WANG S,et al.Evaluation of an interlaced triple procedure:penetrating keratoplasty,extracapsular cataract extraction,and nonopen-sky intraocular lens implantation[J].Medicine (Baltimore),2017,96(35):e7656.
[4] BURDON MA,MCDONNELL P.A survey of corneal graft practice in the United Kingdom[J].Eye (Lond),1995,9(6):6-12.
[5] INOUE Y.Corneal triple procedure[J].Semin Ophthalmol,2001,16(3):113-118.
[6] SHIMMURA S,OHASHI Y,SHIROMA H,SHIMAZAKI J,TSUBOTA K.Corneal opacity and cataract:triple procedure versus secondary approach[J].Cornea,2003,22(3):234-238.
[7] AL-MOHAIMEED MM.Graft survival and visual outcome after simultaneous penetrating keratoplasty and cataract extraction[J].Int J Ophthalmol,2013,6(3):385-389.
[8] BERSUDSKY V,REHANY U,RUMELT S.Risk factors for failure of simultaneous penetrating keratoplasty and cataract extraction[J].J Cataract Refract Surg,2004,30(9):1940-1947.
[9] DAVIS EA,AZAR DT,JAKOBS FM,STARK WJ.Refractive and keratometric results after the triple procedure:experience with early and late suture removal[J].Ophthalmology,1998,105(4):624-630.
[10] HIGAKI S,FUKUDA M,MATSUMOTO C,SHIMOMURA Y.Results of penetrating keratoplasty triple procedure with 25-gauge core vitrectomy[J].Cornea,2012,31(7):730-733.
[11] WILLIAMS KA,LOWE M,BARTLETT C,KELLY TL,COSTER DJ.Risk factors for human corneal graft failure within the Australian corneal graft registry[J].Transplantation,2008,86(12):1720-1724.
[12] NGUYEN D Q,MUMFORD L L,JONES MN,ARMITAGE WJ,COOK SD,KAYE SB,et al.The visual and refractive outcomes of combined and sequential penetrating keratoplasty,cataract extraction,and intraocular lens insertion[J].Eye (Lond),2009,23(6):1295-1301.
[13] GREEN M,CHOW A,APEL A.Outcomes of combined penetrating keratoplasty and cataract extraction compared with penetrating keratoplasty alone[J].Clin Exp Ophthalmol,2007,35(4):324-329.
[14] CAZABON S,QUAH SA,JONES MN.Sequential versus combined penetrating keratoplasty and cataract surgery[J].Optom Vis Sci,2010,87(7):482-486.
[15] JAVADI MA,FEIZI S,MOEIN HR.Simultaneous penetrating keratoplasty and cataract surgery[J].J Ophthalmic Vis Res,2013,8(1):39-46.
[16] JONAS JB,RANK RM,BUDDE WM,SAUDER G.Factors influencing visual outcome after penetrating keratoplasty combined with intraocular lens implantation[J].Eur J Ophthalmol,2003,13(2):134-138.
[17] FEIZI S,ZARE M.Current approaches for management of postpenetrating keratoplasty astigmatism[J].J Ophthalmol,2011,2011:708736.
[18] LV L,WANG RG,ZOU LH,KANG HJ.The triple procedure and the changes in cornea refractive power after penetrating keratoplasty[J].Chin J Pract Ophthalmol,2001,19(6):456-458.
吕岚,王荣光,邹留河,康惠娟.穿透性角膜移植术后角膜屈光力改变与三联手术[J].中国实用眼科杂志,2001,19(6):456-458.
[19] HAYASHI K,HAYASHI H.Simultaneous versus sequential penetrating keratoplasty and cataract surgery[J].Cornea,2006,25(9):1020-1025.
[20] GRUENAUER-KLOEVEKORN C,KLOEVEKORN-NORGALL K,DUNCKER GI,HABERMANN A.Refractive error after triple and non-simultaneous procedures:is the application of a standard constant keratometry value in IOL power calculation advisable[J]?Acta Ophthalmol Scand,2006,84(5):679-683.
[21] SERDAREVIC ON,RENARD GJ,POULIQUEN Y.Videokeratoscopy of recipient peripheral corneas in combined penetrating keratoplasty,cataract extraction,and lens implantation[J].Am J Ophthalmol,1996,122(1):29-37.

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备注/Memo

备注/Memo:
国家自然科学基金资助(编号:81170824);北京市自然科学基金资助(编号:7182037);卫生系统高层次卫生技术人才培养计划课题基金资助(编号:2013-3-055)
更新日期/Last Update: 2018-04-02