[1]陶天畅,李根林.牛磺酸生物学特性及其在视网膜病变治疗中的应用[J].眼科新进展,2018,38(2):179-183.[doi:10.13389/j.cnki.rao.2018.0041]
　TAO Tian-Chang,LI Gen-Lin.Taurine for the treatment of retinopathy and its biochemical features[J].Recent Advances in Ophthalmology,2018,38(2):179-183.[doi:10.13389/j.cnki.rao.2018.0041]
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牛磺酸生物学特性及其在视网膜病变治疗中的应用/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
38卷
期数:
2018年2期
页码:
179-183
栏目:
文献综述
出版日期:
2018-02-05

文章信息/Info

Title:
Taurine for the treatment of retinopathy and its biochemical features
作者:
陶天畅; 李根林
100730　北京市，首都医科大学附属北京同仁医院北京同仁眼科中心，北京市眼科学与视觉科学重点实验室
Author(s):
TAO Tian-Chang; LI Gen-Lin
Beijing Ophthalmology & Visual Sciences Key Lab，Beijing Tongren Eye Center，Beijing Tongren Hospital，Capital Medical University，Beijing 100730，China
关键词:
牛磺酸; 生物学特性; 视网膜疾病
Keywords:
taurine; biochemical features; retinopathy
分类号:
R774.1
DOI:
10.13389/j.cnki.rao.2018.0041
文献标志码:
A
摘要:
牛磺酸是一种特殊的非蛋白氨基酸，可以促进视网膜的分化和发育，具有影响一氧化氮活性、降低自由基含量、抗脂质过氧化反应、调节Ca2+浓度及拮抗谷氨酸兴奋毒性等生物学特性。鉴于牛磺酸上述特性，对视网膜光损伤、视网膜色素变性、糖尿病视网膜病变等视网膜疾病行牛磺酸治疗可作为一种方法和途径，本文就牛磺酸的生物学特性及其在视网膜疾病治疗中的研究现状和进展做一综述。
Abstract:
The taurine is one special kind of non-protein amino acid，possessing biochemical characteristics including regulation of NO activity，reduction of the content of free radical，anti-lipid peroxidation，regulation of calcium concentration，antagonism of glutamate toxicity，which can promote the differentiation and development of the retina.Given the characteristics above，taurine can be applied in the treatment of retinal diseases such as light-induced retinal injury，retinitis pigmentosa and diabetic retinopathy，and this paper will give a review about taurine for the treatment of retinopathy and its biochemical features.

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备注/Memo

备注/Memo:
国家自然科学基金资助（编号：81271046）
更新日期/Last Update: 2018-02-02