参考文献/References:
[1] SARWAR S,BAKBAK B,SADIQ MA,SEPAH YJ,SHAH SM,IBRAHIM M,et al.Fusion proteins:aflibercept(VEGF Trap-Eye)[J].Dev Ophthalmol,2016,55:282-294.
[2] HOLASH J,DAVIS S,PAPADOPOULOS N,CROLL SD,HO L,RUSSELL M,et al.VEGF-Trap:a VEGF blocker with potent antitumor effects[J].Proc Natl Acad Sci USA,2002,99(17):11393-11398.
[3] DE OLIVEIRA DIAS JR,DE ANDRADE GC,NOVAIS EA,FARAH ME,RODRIGUES EB.Fusion proteins for treatment of retinal diseases:aflibercept,ziv-aflibercept,and conbercept[J].Int J Retina Vitreous,2016,2(1):3.
[4] OLSSON AK,DIMBERG A,KREUGER J,CLAESSON-WELSH L.VEGF receptor signalling-in control of vascular function[J].Nat Rev Mol Cell Biol,2006,7(5):359-371.
[5] RUDGE JS,THURSTON G,DAVIS S,PAPADOPOULOS N,GALE N,WIEGAND SJ,et al.VEGF trap as a novel antiangiogenic treatment currently in clinical trials for cancer and eye diseases,and VelociGene-based discovery of the next generation of angiogenesis targets[J].Cold Spring Harb Symp Quant Biol,2005,70:411-418.
[6] CURSIEFEN C,CHEN L,BORGES LP,JACKSON D,CAO J,RADZIEJEWSKI C,et al.VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment[J].J Clin Invest,2004,113(7):1040-1050.
[7] LOWE J,ARAUJO J,YANG J,REICH M,OLDENDORP A,SHIU V,et al.Ranibizumab inhibits multiple forms of biologically active vascular endothelial growth factor in vitro and in vivo[J].Exp Eye Res,2007,85(4):425-430.
[8] BAKRI SJ,SNYDER MR,REID JM,PULIDO JS,EZZAT MK,SINGH RJ.Pharmacokinetics of intravitreal ranibizumab(Lucentis)[J].Ophthalmology,2007,114(12):2179-2182.
[9] BAKRI SJ,SNYDER MR,REID JM,PULIDO JS,SINGH RJ.Pharmacokinetics of intravitreal bevacizumab(Avastin)[J].Ophthalmology,2007,114(5):855-859.
[10] STEWART MW,ROSENFELD PJ.Predicted biological activity of intravitreal VEGF Trap[J].Br J Ophthalmol,2008,92(5):667-668.
[11] JULIEN S,BIESEMEIER A,TAUBITZ T,SCHRAERMEYER U.Different effects of intravitreally injected ranibizumab and aflibercept on retinal and choroidal tissues of monkey eyes[J].Br J Ophthalmol,2014,98(6):813-825.
[12] NGUYEN QD,SHAH SM,BROWNING DJ,HUDSON H,SONKIN P,HARIPRASAD SM,et al.A phase I study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration[J].Ophthalmology,2009,116(11):2141-2148.
[13] BROWN DM,HEIER JS,CIULLA T,BENZ M,ABRAHAM P,YANCOPOULOS G,et al.Primary endpoint results of a phase II study of vascular endothelial growth factor trap-eye in wet age-related macular degeneration[J].Ophthalmology,2011,118(6):1089-1097.
[14] HEIER JS,BROWN DM,CHONG V,KOROBELNIK JF,KAISER PK,NGUYEN QD,et al.Intravitreal aflibercept(VEGF trap-eye) in wet age-related macular degeneration[J].Ophthalmology,2012,119(12):2537-2548.
[15] NGUYEN QD,CAMPOCHIARO PA,SHAH SM,BROWNING DJ,HUDSON HL,SONKIN PL,et al.Evaluation of very high-and very low-dose intravitreal aflibercept in patients with neovascular age-related macular degeneration[J].J Ocul Pharmacol Ther,2012,28(6):581-588.
[16] HEIER JS,BOYER D,NGUYEN QD,MARCUS D,ROTH DB,YANCOPOULOS G,et al.The 1-year results of CLEAR-IT 2,a phase 2 study of vascular endothelial growth factor trap-eye dosed as-needed after 12-week fixed dosing[J].Ophthalmology,2011,118(6):1098-1106.
[17] DO DV,SCHMIDT-ERFURTH U,GONZALEZ VH,GORDON CM,TOLENTINO M,BERLINER AJ,et al.The DA VINCI Study:phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema[J].Ophthalmology,2011,118(9):1819-1826.
[18] DO DV,NGUYEN QD,BOYER D,SCHMIDT-ERFURTH U,BROWN DM,VITTI R,et al.One-year outcomes of the da Vinci Study of VEGF Trap-Eye in eyes with diabetic macular edema[J].Ophthalmology,2012,119(8):1658-1665.
[19] KOROBELNIK JF,DO DV,SCHMIDT-ERFURTH U,BOYER DS,HOLZ FG,HEIER JS,et al.Intravitreal aflibercept for diabetic macular edema[J].Ophthalmology,2014,121(11):2247-2254.
[20] CAMPOCHIARO PA,CLARK WL,BOYER DS,HEIER JS,BROWN DM,VITTI R,et al.Intravitreal aflibercept for macular edema following branch retinal vein occlusion:the 24-week results of the VIBRANT study[J].Ophthalmology,2015,122(3):538-544.
[21] WELLS JA,GLASSMAN AR,AYALA AR,JAMPOL LM,BRESSLER NM,BRESSLER SB,et al.Aflibercept,bevacizumab,or ranibizumab for diabetic macular edema:two-year results from a comparative effectiveness randomized clinical trial[J].Ophthalmology,2016,123(6):1351-1359.
[22] HEIER JS,CLARK WL,BOYER DS,BROWN DM,VITTI R,BERLINER AJ,et al.Intravitreal aflibercept injection for macular edema due to central retinal vein occlusion:two-year results from the COPERNICUS study[J].Ophthalmology,2014,121(7):1414-1420.
[23] OGURA Y,ROIDER J,KOROBELNIK JF,HOLZ FG,SIMADER C,SCHMIDT-ERFURTH U,et al.Intravitreal aflibercept for macular edema secondary to central retinal vein occlusion:18-month results of the phase 3 GALILEO study[J].Am J Ophthalmol,2014,158(5):1032-1038.
[24] BOYER D,HEIER J,BROWN DM,CLARK WL,VITTI R,BERLINER AJ,et al.Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion:six-month results of the phase 3 COPERNICUS study[J].Ophthalmology,2012,119(5):1024-1032.
[25] CLARK WL,BOYER DS,HEIER JS,BROWN DM,HALLER JA,VITTI R,et al.Intravitreal aflibercept for macular edema following branch retinal vein occlusion:52-week results of the VIBRANT Study[J].Ophthalmology,2016,123(2):330-336.
[26] IKUNO Y,OHNO-MATSUI K,WONG TY,KOROBELNIK JF,VITTI R,LI T,et al.Intravitreal aflibercept injection in patients with myopic choroidal neovascularization:The MYRROR Study[J].Ophthalmology,2015,122(6):1220-1227.
[27] PITCHER JD,WITKIN AJ,DECROOS FC,HO AC.A prospective pilot study of intravitreal aflibercept for the treatment of chronic central serous chorioretinopathy:the CONTAIN study[J].Br J Ophthalmol,2015,99(6):848-852.
[28] KOWALCZUK L,MATET A,DIRANI A,DARUICH A,AMBRESIN A,MANTEL I,et al.Efficacy of intravitreal aflibercept in macular telangiectasia type 1 is linked to the ocular angiogenic profile[J].Retina,2016,36(1):28-36.
[29] SUKGEN EA,SOKER G,KOCLUK Y,GULEK B.Effect of intravitreal aflibercept on central retinal arterial blood flow in type 1 retinopathy of prematurity[J].Eur J Ophthalmol,2017,101(6):231-240.
[30] SCHATZ P,SKARIN A,LAVAQUE AJ,LIMA LH,AREVALO JF.Preservation of macular structure and function after intravitreal aflibercept for choroidal neovascularization associated with serpiginous choroiditis[J].Acta Ophthalmol,2016,94(8):839-841.
[31] BRAIMAH IZ,STEWART M,VIDEKAR C,DEDHIA CJ,CHHABLANI J.Intravitreal ziv-aflibercept for the treatment of choroidal neovascularisation associated with conditions other than age-related macular degeneration[J].Br J Ophthalmol,2017,101(6):130-195.
[32] TOUSSAINT BW,KITCHENS JW,MARCUS DM,MILLER DM,KINGDON ML,HOLCOMB D,et al.Intravitreal aflibercept injection for choroidal neovascularization due to presumed ocular histoplasmosis syndrome:The HANDLE Study[J].Retina,2017,37(8):1617-1619.
相似文献/References:
[1]程文武 江萍 席祖莲 张汉武 訾世莉 聂军 董彩虹.蛹虫草提取物抑制大鼠角膜新生血管的实验研究[J].眼科新进展,2012,32(5):000.
[2]于静 张明昌.苦参碱对大鼠角膜新生血管的抑制作用[J].眼科新进展,2012,32(6):000.
[3]吴正正 严京 接传红 高健生 陈皆春 宋剑涛.密蒙花方对缺氧状态下脐静脉血管内皮细胞 VEGF-VEGFR 信号转导通路的影响[J].眼科新进展,2012,32(7):000.
[4]庞霞 曲蕴慧 马跃伟 张效房 董敬民 高冬玲.去整合素金属蛋白酶9和血管内皮生长因子蛋白在眼部恶性黑色素瘤中的表达[J].眼科新进展,2012,32(7):000.
[5]李艳 李筱荣 袁佳琴 潘斌.糖尿病大鼠视网膜中VEGF、PEDF的表达与血-视网膜屏障损伤[J].眼科新进展,2013,33(1):000.
[6]许琴 黄亮 林素香 郑水华 肖煜晨 王雅丽.激光诱导小鼠脉络膜新生血管中膜攻击物与血管生长因子的表达[J].眼科新进展,2013,33(8):000.
[7]李小璐 马雅玲.糖尿病视网膜病变大鼠视网膜VEGF和PEDF的动态表达[J].眼科新进展,2013,33(9):000.
[8]曾莉 常以力 邵毅.血管内皮生长因子反义寡脱氧核苷酸联合血管生成素-1对糖尿病视网膜病变大鼠视网膜血管渗漏及新生血管生成的影响[J].眼科新进展,2012,32(10):000.
[9]兰兰 惠延年 曾光伟.血管生成素-1对糖尿病大鼠视网膜微血管病变、基质金属蛋白酶和血管内皮生长因子的抑制作用[J].眼科新进展,2012,32(10):000.
[10]谢明捷 吕红彬 何跃 赵春会.炎症因子与糖尿病视网膜病变相关性研究进展[J].眼科新进展,2012,32(10):000.
[11]卢谦益.阿柏西普经玻璃体内注射治疗糖尿病黄斑水肿的临床疗效[J].眼科新进展,2019,39(4):340.[doi:10.13389/j.cnki.rao.2019.0076]
LU Qian-Yi.Intravitreal aflibercept injection for the treatment of diabetic macular edema[J].Recent Advances in Ophthalmology,2019,39(9):340.[doi:10.13389/j.cnki.rao.2019.0076]
[12]张国明,田娅.阿柏西普在眼科疾病治疗中的应用[J].眼科新进展,2020,40(1):001.[doi:10.13389/j.cnki.rao.2020.0001]
ZHANG Guoming,TIAN Ya.Advances in application of Aflibercept for treatment of ocular diseases[J].Recent Advances in Ophthalmology,2020,40(9):001.[doi:10.13389/j.cnki.rao.2020.0001]