[1]吕勇,丁慧芳,杨琳,等.白内障超声乳化吸出术后并发前部缺血性视神经病变(AION)危险因素分析[J].眼科新进展,2017,37(4):351-353.[doi:10.13389/j.cnki.rao.2017.0089]
 LV Yong,DING Hui-Fang,YANG Lin,et al.Risk factors of anterior ischemic optic neuropathy after phacoemulsification[J].Recent Advances in Ophthalmology,2017,37(4):351-353.[doi:10.13389/j.cnki.rao.2017.0089]
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白内障超声乳化吸出术后并发前部缺血性视神经病变(AION)危险因素分析/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年4期
页码:
351-353
栏目:
应用研究
出版日期:
2017-04-05

文章信息/Info

Title:
Risk factors of anterior ischemic optic neuropathy after phacoemulsification
作者:
吕勇丁慧芳杨琳谭凤玲
450052 河南省郑州市,郑州大学医学院第一附属医院眼科
Author(s):
LV YongDING Hui-FangYANG LinTAN Feng-Ling
Department of Ophthalmology,the First Affiliated Hospital,Medical College of Zhengzhou University,Zhengzhou 450052,Henan Province,China
关键词:
白内障前部缺血性视神经病变颈动脉疾病
Keywords:
cataractanterior ischemic optic neuropathycarotid artery disease
分类号:
R776.1
DOI:
10.13389/j.cnki.rao.2017.0089
文献标志码:
A
摘要:
目的 筛选出白内障超声乳化吸出术后并发前部缺血性视神经病变(anterior ischemic optic neuropathy,AION)的危险因素,初步探讨术后并发AION的发病机制。方法 收集2010年9月1日至2016年9月1日在郑州大学第一附属医院眼科行白内障超声乳化吸出术的手术病例,符合条件的病例为11 206例(13 320眼),其中白内障术后并发AION 30例30眼(AION组),以1∶3比例在纳入的其余病例中随机选取90例90眼作为对照组。记录AION组和对照组小视盘、既往手术史、心脏病、糖尿病、高血压、高脂血症、吸烟、颈动脉疾病、眼压等情况,采用χ2检验、Logistic 回归分析、t检验,筛选出白内障术后并发AION的相关因素及危险因素。结果 小视盘、糖尿病、高血压、高脂血症、颈动脉疾病为白内障术后并发AION的相关因素。高脂血症、颈动脉疾病为白内障术后并发AION的危险因素。术前两组患者眼压差异无统计学意义(P>0.05);术后1 d和7 d AION组眼压均高于对照组,差异均有统计学意义(均为P<0.05)。结论 高脂血症、颈动脉疾病均为白内障术后发生AION的危险因素,术后眼压高可能是发生AION的诱因。
Abstract:
Objective To select the risk factors and focus on the pathogenesis of anterior ischemic optic neuropathy (AION) after cataract surgery.Methods A retrospective review of all patients with phacoemulsification surgery referred to the Ophthalmology Divisions,the First Affiliated Hospital,Zhengzhou University,from September 1,2010 to September 1,2016 was performed.Eligible patients were 11 206 cases(13 320 eyes),30 cases (30 eyes) were complicated with AION after cataract surgery (AION group),and 90 cases (90 eyes) were selected as control group according to the ratio of 1∶3 by random sequence.Factors of small cup disc ratios,previous surgery history,cardiac disease,diabetes,hypertension,hyperlipemia,smoking,carotid disease and intraocular pressure(IOP) were collected,χ2test,Logistic regression and t test were performed to analyze risk factors for AION.Results Small cup-disc ratios,diabetes,hypertension,hyperlipemia,carotid disease were influencing factors of AION after cataract surgery.Hyperlipemia and carotid disease were risk factors of AION after cataract surgery.There was no significant difference in preoperative intraocular pressure between two groups(all P>0.05).The intraocular pressure at postoperative 1 day and 7 days in AION group were higher than those in control group (all P<0.05).Conclusion Hyperlipemia and carotid artery disease are risk factors for AION after cataract surgery,and high intraocular pressure may be the inductive factor of AION.

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备注/Memo

备注/Memo:
河南省重点科技攻关项目(编号:072102310116)
更新日期/Last Update: 2017-04-26