[1]刘桂华,谷天瀑,李颖,等.角膜塑形镜配戴后瞳孔与光学区的大小对视觉质量的影响[J].眼科新进展,2017,37(1):038-41.[doi:10.13389/j.cnki.rao.2017.0010]
　LIU Gui-Hua,GU Tian-Pu,LI Ying,et al.Effects of pupil size and treatment zone diameter on optical quality after myopic orthokeratology treatment[J].Recent Advances in Ophthalmology,2017,37(1):038-41.[doi:10.13389/j.cnki.rao.2017.0010]
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角膜塑形镜配戴后瞳孔与光学区的大小对视觉质量的影响/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
37卷
期数:
2017年1期
页码:
038-41
栏目:
应用研究
出版日期:
2017-01-05

文章信息/Info

Title:
Effects of pupil size and treatment zone diameter on optical quality after myopic orthokeratology treatment
作者:
刘桂华; 谷天瀑; 李颖; 厉娜; 林伟平; 贺美男; 李静; 魏瑞华
300384　天津市，天津医科大学眼科医院
Author(s):
LIU Gui-Hua; GU Tian-Pu; LI Ying; LI Na; LIN Wei-Ping; HE Mei-Nan; LI Jing; WEI Rui-Hua
Eye Hospital of Tianjin Medical University，Tianjin 300384，China
关键词:
角膜塑形镜; 视觉质量; 瞳孔; 光学区
Keywords:
orthokeratology; visual quality; pupil size; treatment zone
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2017.0010
文献标志码:
A
摘要:
目的　探究角膜塑形镜治疗后暗室对比敏感度与调制传递函数截止频率（modulation transfer function cutoff，MTF cutoff）变化，并分析瞳孔与光学区的大小对暗室下对比敏感度以及MTF cutoff的影响。方法　选取2015年8月至12月在天津医科大学眼科医院进行角膜塑形镜治疗的近视青少年40人（右眼40眼），戴镜前、戴镜后6个月分别测量角膜地形图、暗室瞳孔大小、光学区大小、暗室及暗室眩光条件下对比敏感度曲线下面积（area under log contrast sensitivity function，AULCSF）及MTF cutoff，戴镜前后视觉质量参数变化采用配对t检验，暗室瞳孔与光学区对视觉质量参数的影响采用Pearson相关分析。结果　戴镜后6个月等效球镜度数降低（P<0.001），柱镜度数无变化（P=0.879）；暗室对比敏感度及暗室眩光条件下对比敏感度均下降（均为P<0.001）；MTF cutoff下降（P<0.001）。戴镜前后瞳孔直径为(6.50±0.34)mm。戴镜后6个月光学区直径为(4.05±0.24)mm。暗室条件下AULCSF变化与暗室瞳孔直径及光学区直径均不相关（r=0.159，P=0.307;r=-0.223，P=0.167），暗室眩光条件下AULCSF变化与暗室瞳孔直径及光学区直径均不相关（r=0.174，P=0.289;r=-0.200，P=0.216）。MTF cutoff变化与暗室瞳孔直径及光学区直径相关（r=0.509，P=0.001;r=-0.511，P=0.001），暗室、暗室眩光条件下AULCSF及MTF cutoff变化均与瞳孔直径和光学区直径之差相关（均为P<0.05）。结论　角膜塑形镜配戴后暗室对比敏感度及MTF cutoff均降低，且较小的暗室瞳孔与较大的光学区可获得更好的视觉质量。
Abstract:
Objective　To analyze the changes in contrast sensitivity and modulation transfer function cutoff values (MTF cutoff) after orthokeratology (ortho-k) treatment and its correlation with the magnitude of pupil and the diameter of the treatment zone.Methods　A prospective study was conducted in 40 eyes of 40 patients wearing orthokeratology contact lens.Mesopic area under log contrast sensitivity function (AULCSF) with and without glare and MTF cutoff were measured and compared before and 6 months after ortho-k lens treatment.The magnitude of pupil and diameter of the treatment zone (TxZ) were tested against the change in AULCSF and MTF cutoff after ortho-k treatment in Pearson correlation test.Results　After 6 months of ortho-k treatments,the mean spherical refractive error significantly decreased（P<0.001），but refractive astigmatism did not significantly change (P=0.879).The mesopic AULCSF with and without glare and MTF cutoff significantly decreased after ortho-k lens wear (all P<0.001).The mean pupil size was (6.50±0.34)mm;The mean TxZ diameter was (4.05±0.24)mm.The mesopic AULCSF with and without glare was significantly correlated with the difference between the magnitude of pupil and the diameter of the TxZ (Dpupil-TxZ)(P=0.019,r=0.368;P=0.034,r=0.336,respectively),but not with the magnitude of pupil (r=0.159,P=0.307;r=-0.223,P=0.167,respectively) and the diameter of the TxZ (P=0.289,r=0.174;P=0.216,r=-0.200,respectively).The MTF cutoff was significantly correlated with the magnitude of pupil and diameter of the TxZ and Dpupil-TxZ (P=0.001,r=0.509;P=0.001,r=-0.511,respectively).Conclusion　The contrast sensitivity and MTF cutoff decreases after ortho-k treatment,which can be alleviated by a smaller pupil size and a larger TxZ diameter.

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备注/Memo

备注/Memo:
天津科委自然科学基金资助（编号：11JCYBJC26000）
更新日期/Last Update: 2017-02-15