[1]石路漫,雷方,陈彬川,等.白内障超声乳化吸出术后视网膜中央动脉阻塞风险因素分析[J].眼科新进展,2016,36(11):1047-1050.[doi:10.13389/j.cnki.rao.2016.0279]
　SHI Lu-Man,LEI Fang,CHEN Bin-Chuan,et al.Risk factors of central retinal artery occlusion after phacoemulsification[J].Recent Advances in Ophthalmology,2016,36(11):1047-1050.[doi:10.13389/j.cnki.rao.2016.0279]
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白内障超声乳化吸出术后视网膜中央动脉阻塞风险因素分析
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
36卷
期数:
2016年11期
页码:
1047-1050
栏目:
应用研究
出版日期:
2016-11-05

文章信息/Info

Title:
Risk factors of central retinal artery occlusion after phacoemulsification
作者:
石路漫; 雷方; 陈彬川; 徐一帆; 李帅飞
450014　河南省郑州市，郑州大学第二附属医院眼科（石路漫，陈彬川，徐一帆，李帅飞）；471023　河南省洛阳市，河南科技大学（雷方）
Author(s):
SHI Lu-Man; LEI Fang ; CHEN Bin-Chuan ; XU Yi-Fan ;  LI Shuai-Fei
Department of Ophthalmology, the Second Affiliated Hospital of Zhengzhou University ( SHI Lu-Man , CHEN Bin-Chuan, XU Yi-Fan. LI Shuai-Fei ) , Zhengzhou 450014 , Henan Province , China ; Henan University of Science and Technology ( LEI Fang) , Luoyang 47 1023 , Henan Province , China
关键词:
白内障超声乳化吸出术; 视网膜中央动脉阻塞; 危险因素
Keywords:
phacoemulsification;  central retinal artery occlusion ;  risk factor
分类号:
Ｒ７７９.６６
DOI:
10.13389/j.cnki.rao.2016.0279
文献标志码:
A
摘要:
目的　探讨白内障超声乳化吸出术后发生视网膜中央动脉阻塞（ｃｅｎｔｒａｌｒｅｔｉｎａｌａｒｔｅｒｙｏｃｃｌｕｓｉｏｎ，ＣＲＡＯ）的风险因素及相关预后情况。方法　本研究为病例对照研究。收集２００９年１月至２０１５年１２月在郑州大学第二附属医院眼科行白内障超声乳化吸出术的连续病例８３６５例，纳入７２８３例（９１００眼），统计ＣＲＡＯ例数７例（即ＣＲＡＯ组），利用随机数列法，以１８比例在纳入病例中随机选取５６例（５６眼）作为对照组，若入选者为ＣＲＡＯ患者则剔除，继续选择。统计白内障核硬度、术前最佳矫正视力、眼压、麻醉方式、术中后囊膜破裂情况、全身疾病等，采用Ｆｉｓｈｅｒ确切概率法、ｔ检验、Ｌｏｇｉｓｔｉｃ回归等统计学方法分析ＣＲＡＯ的风险因素。结果　球后麻醉（风险比３．３０７，Ｐ＝０．０１２）、后囊膜破裂（风险比４．２８７，Ｐ＝０．０３４）是术后ＣＲＡＯ发生的危险因素，高血压、颈动脉斑块患者ＣＲＡＯ发生率与对照组相比差异均有统计学意义（均为Ｐ＜０．０１），是危险因素。而术前最佳矫正视力（≤０．０１）、高度近视、青光眼病史、糖尿病病史等差异对于ＣＲＡＯ发生并无统计学意义（均为Ｐ＞０．０５）。结论　高血压、颈动脉斑块、球后麻醉及后囊膜破裂均为白内障超声乳化吸出术后ＣＲＡＯ发生的危险因素。
Abstract:
Objective To demonstrate the risk factors of the complication central retinal artery occlusion( CRAO ) after the cataract surgery of phacoemulsification as well as to find preventions to avoid it. Methods A retrospective study was designed with a total of 7283 cases (9100 eyes) in 8365 patients, which included 7 cases with CRAO ,we selected 56 cases ( 56 eyes) of patients as control group according to the ratio of I : 8 by random sequence. As if the list was the patient with CRAO ,it should be removed. The cataract phacoemulsification was performed in the Second Affiliated Hospital of Zhengzhou University from January 2009 to December 2015. The incidence of CRAO and the risk factors were taken as the main outcomes. The variables of nuclear stages and best correct visual acuity ,intraocular pressure and anesthesia methods , posterior capsular rupture and other diseases were collected and analyzed. Fisher exact probability method, t test, Logistic regression and other statistical methods were performed to analyze risk factors for CRAO. Results Retrobulbar ( risk rati0 3. 307 .P = 0. 012) , posterior capsular rupture ( risk rati0 4. 287 ,P = 0. 034 ) were risk factors for postoperative CRAO. Hypertension and carotid artery plaque in patients with CRAO incidence were risk factors. Compared with control group, the difference was statistically significant ( P < 0. 01 ) . And nuclear hardness grading , preoperative best corrected visual acuity , high myopia, history of glaucoma. diabetes etc. had no statistically difference for CRAO ( all P > 0. 05 ) . Conclusion Hypertension , carotid artery plaques , retrobulbar anesthesia and posterior capsular rupture are the risk factors of CRAO after cataract surgery.

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备注/Memo

备注/Memo:
郑州市科技局基金资助（编号：１２１ＰＣＸＴＤ５２３）
更新日期/Last Update: 2016-11-29