[1]王净莉,万新顺,李彦.间接光凝和直接光凝治疗中心性浆液性脉络膜视网膜病变的疗效对比观察[J].眼科新进展,2016,36(5):477-480.[doi:10.13389/j.cnki.rao.2016.0128]
　WANG Jing-Li,WAN Xin-Shun,LI Yan.Comparative evaluation of indirect and direct laser photocoagulation for central serous chorioretinopathy[J].Recent Advances in Ophthalmology,2016,36(5):477-480.[doi:10.13389/j.cnki.rao.2016.0128]
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间接光凝和直接光凝治疗中心性浆液性脉络膜视网膜病变的疗效对比观察
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
36卷
期数:
2016年5期
页码:
477-480
栏目:
应用研究
出版日期:
2016-05-05

文章信息/Info

Title:
Comparative evaluation of indirect and direct laser photocoagulation for central serous chorioretinopathy
作者:
王净莉; 万新顺; 李彦
453003　河南省新乡市，新乡医学院（王净莉）；453003　河南省新乡市，新乡医学院第三附属医院眼科（万新顺，李彦）
Author(s):
WANG Jing-Li ; WAN Xin-Shun ;  LI Yan
Xinxiang Medical University ( WANG Jing-Li) , Xinxiang 453003 , Henan Province , China; Department of Ophthalmology, the Third Affiliated Hospital of Xinxiang Medical University ( WAN Xin-Shun. LI Yan ) , Xinxiang 453003 , Henan Province , China
关键词:
中心性浆液性脉络膜视网膜病变; 间接光凝疗法; 眼底荧光血管造影; 黄斑中心凹视网膜厚度
Keywords:
central serous chorioretinopathy ;  indirect laser photocoagulation ;  fundus fluorescein angiography ;  central foveal thickness
DOI:
10.13389/j.cnki.rao.2016.0128
文献标志码:
A
摘要:
目的　评价间接光凝治疗中心性浆液性脉络膜视网膜病变（ｃｅｎｔｒａｌｓｅｒｏｕｓｃｈｏｒｉｏｒｅｔｉｎｏｐａｔｈｙ，ＣＳＣ）的临床疗效。方法　ＣＳＣ患者４１例（４２眼），对渗漏点位于黄斑中心凹１／３ＰＤ（５００μｍ）以内的２０眼进行间接光凝为观察组，对渗漏点位于黄斑中心凹１／３ＰＤ（５００μｍ）以外的２２眼进行直接光凝为对照组，于治疗前及治疗后１周、１个月、２个月、３个月检查并记录最佳矫正视力（ｂｅｓｔｃｏｒｒｅｃｔｅｄｖｉｓｕａｌａｃｕｉｔｙ，ＢＣＶＡ）、眼底、黄斑中心凹视网膜厚度（ｃｅｎｔｒａｌｆｏｖｅａｌｔｈｉｃｋｎｅｓｓ，ＣＦＴ）等情况并进行比较。结果　观察组、对照组治疗前ＢＣＶＡ分别为０．５９±０．２０、０．６０±０．２２，治疗后３个月分别为０．９０±０．１８、０．９１±０．０４，两组治疗后视力均明显提高，差异均有统计学意义（均为Ｐ＜０．０１）；两组间相比，治疗前与治疗后３个月ＢＣＶＡ差异均无统计学意义（均为Ｐ＞０．０５）。两组治疗后不同时间点ＣＦＴ均低于治疗前，差异有统计学意义（均为Ｐ＜０．０１）；两组治疗后１个月ＣＦＴ均低于治疗后１周，差异均有统计学意义（均为Ｐ＜０．０１），治疗后１个月、２个月、３个月ＣＦＴ比较，差异均无统计学意义（均为Ｐ＞０．０５）。两组治疗前及治疗后不同时间点ＣＦＴ组间比较，差异均无统计学意义（均为Ｐ＞０．０５）。结论　和直接光凝相比，间接光凝对ＣＳＣ同样具有良好的疗效，为不能进行直接光凝的旁中心凹渗漏的ＣＳＣ提供了一种安全有效的治疗方法。
Abstract:
Objective To evaluate the clinical effects of indirect laser photocoagulation for central serous chorioretinopathy ( CSC) . Methods Forty-one patients ( 42 eyes) with CSC were divided into two groups based on fundus fluorescein angiography (FFA) :the observation group whose leakage located at l/3 PD (500 ym) near the macula and the control group whose leakage located at l/3 PD ( 500 pm) outside the macula. Twenty eyes of the observation group underwent indirect laser photocoagulation , and twenty-two eyes of the control group underwent direct laser photocoagulation. The follow-up time was 3 months. The best corrected visual acuity( BCVA) , fundus and central foveal thickness ( CFT ) were observed at pre-operation and postoperative lweek.l month .2 months , 3 months , and the results were compared. Results The preoperative BCVA in the observation group and control group were 0. 59 + 0. 20 and 0. 60 +0. 22 , respectively, which at the postoperative 3 months were 0. 90 + 0. 18 and 0. 91 + 0. 04 , respectively , there were statistical differences ( all P < 0. 01 ) . There was no statistical difference in preoperative and postoperative BCVA at 3 months between two groups ( all P > 0. 05 ) . The postoperative CFT at different time of two groups were all lower than pre-operation ( all P < 0. 01 ) ; CFT at postoperative I month of two groups were lower than that at postoperative I week ( aU P < 0. 01 ) , no statistical difference was found among postoperative I month.2 months and 3 months ( all P > 0. 05 ) . There was no statistical difference in preoperative and postoperative CFT at different time between two groups ( all P > 0. 05 ) . Conclusion Indirect laser photocoagulation shows the same effect with direct photocoagulation for CSC. It provides a safe and effective method for CSC with parafoveal leaks.

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更新日期/Last Update: 2016-05-04