[1]刘川,张文强,周和政.原发性开角型青光眼患者确诊时视野损害程度的相关因素分析[J].眼科新进展,2016,36(4):356-358.[doi:10.13389/j.cnki.rao.2016.0096]
　LIU Chuan,ZHANG Wen-Qiang,ZHOU He-Zheng.Relative factor analysis of visual field defect degree when diagnosing primary open-angle glaucoma[J].Recent Advances in Ophthalmology,2016,36(4):356-358.[doi:10.13389/j.cnki.rao.2016.0096]
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原发性开角型青光眼患者确诊时视野损害程度的相关因素分析
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
36卷
期数:
2016年4期
页码:
356-358
栏目:
应用研究
出版日期:
2016-04-05

文章信息/Info

Title:
Relative factor analysis of visual field defect degree when diagnosing primary open-angle glaucoma
作者:
刘川; 张文强; 周和政
430070　湖北省武汉市，南方医科大学附属武汉临床医学院（刘川，周和政）；430070　湖北省武汉市，广州军区武汉总医院眼科（张文强，周和政）
Author(s):
LIU Chuan ; ZHANG Wen-Qiang ; ZHOU He-Zheng
Wuhan Clinical College of Sounhem Medical University ( LIU Chuan, ZHOU He-Zheng ) , Wuhan 430070 , Hubei Province , China ; Department of Ophthalmology, Wuhan General Hospital of Guangzhou Military ( ZHAWG Wen-Qiang, ZHOU He-Zheng) , Wuhan 430070 , Hubei Province . China
关键词:
原发性开角型青光眼; 视野; 相关因素
Keywords:
primary open-angle glaucoma ;  visual field ; relative factor
DOI:
10.13389/j.cnki.rao.2016.0096
文献标志码:
A
摘要:
目的　分析原发性开角型青光眼（ｐｒｉｍａｒｙｏｐｅｎ-ａｎｇｌｅｇｌａｕｃｏｍａ，ＰＯＡＧ）患者确诊时的视野损害程度及其相关因素。方法　收集２０１４年５月至２０１５年１０月在我院门诊就诊的ＰＯＡＧ患者１１３例１１３眼。根据视野损害分级将患者分为早期视野损害组（视野损害０～１级）和中晚期视野损害组（视野损害２～５级）。对两组患者的确诊年龄、性别、身体质量指数、青光眼相关症状、家族史、高度近视、中央角膜厚度、眼压等相关因素进行统计分析。结果　早期视野损害组３１眼（２７．４３％），中晚期视野损害组８２眼（７２．５７％）。早期视野损害组的确诊年龄为（５２．８１±１６．５７）岁，眼压为（２３．６７±１１．４４）ｍｍＨｇ（１ｋＰａ＝７．５ｍｍ-Ｈｇ），与中晚期视野损害组的（４５．６２±１７．１２）岁和（３０．５８±１２．１３）ｍｍＨｇ相比，差异均有统计学意义（Ｐ＝０．０４７、０．００７）；早期视野损害组合并高度近视的患者比例（９．６８％）及有青光眼相关症状的患者比例（２９．０３％）均小于中晚期视野损害组（２９．２７％、５３．６６％），差异均有统计学意义（Ｐ＝０．０２９、０．０１９）。早期视野损害组的性别比例、身体质量指数、家族史、中央角膜厚度与中晚期视野损害组相比，差异均无统计学意义（均为Ｐ＞０．０５）。眼压与患者确诊时的视野损害严重程度呈正相关（ｒ＝０．４１１，Ｐ＝０．０００）。结论　大多数ＰＯＡＧ患者确诊时已发生较严重的视野损害，高眼压、青光眼相关症状、合并高度近视、确诊时年龄偏低可能是ＰＯＡＧ患者确诊时发生较严重视野损害的危险因素。
Abstract:
Objective To analyze the defect degree of visual field when diagnosing primary open-angle glaucoma ( POAG) and its relative factors. Methods A total of 113 0utpatients with POAG were collected from May 2014 to October 2015. Patients were divided into early stage group ( stage 0 - 1) and moderate-advanced stage group ( stage 2 - 5 ) according to the stage of visual field defect. Clinical data including age at diagnosis , gender , body mass index ( BMI) , symptom related to POAG . family history of POAG ,high myopia, central corneal thickness and intraocular pressure ( IOP) were analyzed between two groups. Results There were 31 eyes ( 27. 43% ) in early stage group and 82 eyes (72. 57% ) in moderate-advanced stage group. The age at diagnosis was (52. 81 + 16. 57) years in early stage group and (45. 62 + 17. 12) years in moderate-advanced stage group ,while IOP was (23. 67 + 11. 44 ) mmHg ( I kPa = 7. 5 mmHg) in early stage group and ( 30. 58 + 12. 13) mmHg in moderate-advanced stage group , and the differences were statistically significant ( P = 0. 047 .0. 007 ) . The incidence of high myopia (9. 68% ) and symptom related to POAG (29. 03% ) in early stage group were significantly lower than those in moderate-advanced stage group ( 29. 27% , 53. 66% .P = 0. 029 .0. 019 ) . There was no statistically sigruficant difference in gender , BMI, family history of POAG and central corneal thickness between two groups ( all P > 0. 05 ) . IOP was positively related to visual field defect at the time of diagnosis (r = 0. 4II.P = 0. 000) . Conclrision The majority of patients with POAG have serious visual field defect at the time of diagnosis. High IOP, high myopia, symptom related to POAG and younger age at the time of diagnosis may be risk factors for serious visual field defect when diagnosing POAG.

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更新日期/Last Update: 2016-04-01