[1]任明玉,刘立民,高宇,等.眼眶淋巴组织增生性病变的临床分析[J].眼科新进展,2015,35(10):983-984.[doi:10.13389/j.cnki.rao.2015.0269]
　REN Ming-Yu,LIU Li-Min,GAO Yu,et al.Clinical analysis of orbital lymphoproliferative disorders[J].Recent Advances in Ophthalmology,2015,35(10):983-984.[doi:10.13389/j.cnki.rao.2015.0269]
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眼眶淋巴组织增生性病变的临床分析
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年10期
页码:
983-984
栏目:
应用研究
出版日期:
2015-10-05

文章信息/Info

Title:
Clinical analysis of orbital lymphoproliferative disorders
作者:
任明玉; 刘立民; 高宇; 高占国
054000　河北省邢台市，河北省眼科医院眼眶病科
Author(s):
REN Ming-Yu ;  LIU Li-Min; GAO Yu ; GAO Zhan-Guo
Orbital Department . Eye Hospital of Hebei Province, Xingtai 054000 . Hebei Province . China
关键词:
淋巴组织增生性病变; 眼眶肿瘤; 临床特点
Keywords:
lymphoproliferative disorders ;  orbital tumor;  clinical character
DOI:
10.13389/j.cnki.rao.2015.0269
文献标志码:
A
摘要:
目的　分析眼眶淋巴组织增生性病变患者的临床特点。方法　回顾性分析３１例眼眶淋巴组织增生性病变患者的临床资料，对其年龄、发生部位、病理特点以及其他临床特征进行分析。结果　眼眶淋巴组织增生性病变患者３１例３５眼；年龄３５～８９岁，６０岁以上者１７例；发生于泪腺８例，眶内其他部位２３例。淋巴组织增生４例４眼，淋巴组织非典型增生６例７眼，Ｂ细胞淋巴瘤１８例１９眼，霍奇金淋巴瘤１例２眼，Ｔ细胞淋巴瘤１例１眼，Ｔ／ＮＫ细胞淋巴瘤１例２眼。ＣＴ显示：未发现眶壁骨质受损。ＭＲＩ显示：Ｔ１Ｗ１为中等信号，Ｔ２Ｗ１为中偏高信号，病变可被轻到中度强化，部分明显强化。２例２眼患者侵及眼前节，出现葡萄膜炎表现，３例４眼患者存在全身病灶，１例１眼患者进行骨髓细胞学分析，发现瘤细胞存在。３１例中２５例２５眼完全切除，６例１０眼部分切除，术后给予放射治疗和（或）化学治疗。随访３～１２个月，１例２眼明确复发，５例８眼正在接受治疗，２５例２５眼未发现肿物增长。结论　眼眶淋巴组织增生性病变在临床较为常见，在发病年龄、病变发生部位、影像学以及病理学方面均有其自身特点，正确认识该疾病，对临床诊断与治疗有重要意义。
Abstract:
Objective To analyze the clinical features of orbital lymphoproliferative disorders. Methods Thirty-one patients ( 35 eyes ) with orbital lymphoproliferative disorders were reviewed retrospectively. The onset ages ,location.histological character and other clinical features were analyzed. Results The patients aged from 35 year t0 89 years. There were 8 cases in lacrimal fossa.23 cases in other location of the orbit. Four cases(4 eyes) were lymphoproliferation .6 cases ( 7 eyes) were atypical hyperplasia of lymphoid tissue.18 cases( 19 eyes) were non-Hodgkin lymphoma, I case ( 2 eyes) was Hodgkin lymphoma . I case ( I eye) was T cell lymphoma , I case ( 2 eyes) was T/NK cell lymphoma. The damage of orbital bone was not appeared on CT. All the lesions were medium-intensity septation on TIWI and T2WI , most were mild to moderate enhancement,2 cases were obvious enhancement. Two cases had uveitis, I case had tumor cells which were found in bone marrow. A1l patients were treated by operation, which including 25 cases of total resection. 6 cases of partial resection, radiotherapy and/or chemotherapy were provided after operation. The follow-up period ranged 3 - 12 months , I case(2 eyes) was recurrence ,5 patients( 8 eyes) were receiving treatment .25 cases(25 eyes) did not find tumor growth. Conclusion Orbital lymphoproliferative disorders are common in clinical practice. It has its own character in the onset age ,locations ,imagine appearance and pathology. Identifying the disease correctly has important significance in diagnosing and treating it.

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更新日期/Last Update: 2015-09-30