[1]邵晓蕾,周秀珍,秦波.青少年屈光不正人群中脉络膜厚度的研究[J].眼科新进展,2015,35(10):968-971.[doi:10.13389/j.cnki.rao.2015.0264]
　SHAO Xiao-Lei,ZHOU Xiu-Zhen,QIN Bo.Analysis of choroidal thickness in juvenile ametropia[J].Recent Advances in Ophthalmology,2015,35(10):968-971.[doi:10.13389/j.cnki.rao.2015.0264]
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青少年屈光不正人群中脉络膜厚度的研究
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年10期
页码:
968-971
栏目:
应用研究
出版日期:
2015-10-05

文章信息/Info

Title:
Analysis of choroidal thickness in juvenile ametropia
作者:
邵晓蕾; 周秀珍; 秦波
518020　广东省深圳市，暨南大学第二临床医学院、深圳市人民医院眼科
Author(s):
SHAO Xiao-Lei; ZHOU Xiu-Zhen; QIN Bo
Department of Ophthalmology , Shenzhen People ’s Hospital , Jinan University Second Clinical Medicine College, Shenzhen 518020 , Guangdong Province . China
关键词:
光学相干断层扫描; 增强深度成像; 脉络膜厚度; 屈光不正; 眼轴长度
Keywords:
optical coherence tomography;  enhanced depth imaging;  coroidal thickness ;  refractive error ;  axial length
DOI:
10.13389/j.cnki.rao.2015.0264
文献标志码:
A
摘要:
目的　研究青少年屈光不正患者的脉络膜厚度的特点及其与屈光度、眼轴长度等因素的相关性。方法　随机对在屈光门诊完成验光的５～１８岁屈光不正青少年进行了脉络膜厚度和眼轴长度的测量。最终５１例１０２眼患者纳入研究。使用海德堡频域ＯＣＴ的增强深度成像模式对每眼进行经黄斑中心凹水平方向线性扫描。分别测量该扫描线上５个位点的脉络膜厚度。应用ＩＯＬｍａｓｔｅｒ测量眼轴长度。结果　５１例患者年龄为（１０．０４±２．７８）岁，屈光度为（－１．６１±１．８２）Ｄ，眼轴长度为（２４．１４±１．１４）ｍｍ。扫描线上脉络膜厚度由颞侧向鼻侧逐渐变薄。屈光度与眼轴长度呈显著负相关（Ｒ２＝０．５６２），各位点的脉络膜厚度均与屈光度呈显著正相关（Ｐ＜０．０１），与眼轴长度则呈显著负相关（Ｐ＜０．０５），中心凹鼻侧１ｍｍ处相关性最高。中心凹下的脉络膜厚度与年龄呈显著负相关。结论　后极部脉络膜厚度的改变可能在屈光度及眼轴长度改变相关的病理生理变化中起到重要的作用。
Abstract:
Objective To analyze the characteristics of chorioidal thickness( CT) in juvenile ametropia, and investigate the correlation between refractive error and axial length. Methods Fifty-one juveniles ( 102 eyes) with ametropia were included in this study. CT , diopter and axial length were measured. The EDI mode of OCT was used to do the horizontal linear scan of the central retina. CT was measured in 5 locations on the scaruung line. The axial lengths were measured with IOL master( Zeiss) . Results The mean age of 51 cases was ( 10. 04 + 2. 78) years, the mean refractive error was ( - 1. 61 + 1. 82) D, the mean axial length was ( 24. 14 + 1. 14) mm. CT became thinner from temporal to disc on the scanning line. The refractive error was negative correlated with axial length ( R2 = 0. 562 ) . CT was positive correlated with refractive error ( P < 0. 01) . and negative correlated with axial length ( P < 0. 05 ) , the correlation of CT at I mm around macular fovea was the highest. CT at subfovea showed significantly negative correlation with age. Conclusion Changes of posterior pole CT may play an essential role in the pathophysiological alteration correlated with refractive error and axial length.

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更新日期/Last Update: 2015-09-30