[1]彭坤,郑康铿,陈浩宇,等. 眼前节OCT对角膜穿通伤术后角膜伤口对合及愈合情况的观察[J].眼科新进展,2015,35(9):847-850.[doi:10.13389/j.cnki.rao.2015.0231]
　PENG Kun,ZHENG Kang-Keng,CHEN Hao-Yu,et al. Observation of convolution and healing of corneal wound by anterior segment OCT after corneal penetrating trauma surgery[J].Recent Advances in Ophthalmology,2015,35(9):847-850.[doi:10.13389/j.cnki.rao.2015.0231]
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 眼前节OCT对角膜穿通伤术后角膜伤口对合及愈合情况的观察
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年9期
页码:
847-850
栏目:
应用研究
出版日期:
2015-09-05

文章信息/Info

Title:
 Observation of convolution and healing of corneal wound by anterior segment OCT after corneal penetrating trauma surgery
作者:
 彭坤; 郑康铿; 陈浩宇; 夏红和; 陆雪辉; 金创; 刘昕宇
 515041　广东省汕头市，汕头大学?香港中文大学联合汕头国际眼科中心
Author(s):
 PENG Kun ; ZHENG Kang-Keng ;  CHEN Hao-Yu ;  XIA Hong-He;  LU Xue-Hui; JIN Chuang ;  LIU Xin-Yu
 Joint Shantou International Eye Center of Shantou University and Chinese University of Hong Kong, Shantou 515041 , Guangdong Province , China
关键词:
 ; 前节光学相干断层扫描; 角膜穿通伤; 角膜厚度
Keywords:
 ; anterior segment optical coherence tomography ;  corneal penetrating trauma ;  corneal thickness
DOI:
10.13389/j.cnki.rao.2015.0231
文献标志码:
A
摘要:
 目的　应用眼前节光学相干断层扫描（ａｎｔｅｒｉｏｒｓｅｇｍｅｎｔｏｐｔｉｃａｌｃｏｈｅｒｅｎｃｅｔｏｍｏｇｒａｐｈｙ，ＡＳ-ＯＣＴ）对角膜穿通伤缝合术后的角膜伤口对合及愈合情况进行观察，探讨ＡＳ-ＯＣＴ在角膜伤口愈合过程中的评价作用。方法　回顾性分析２０１２年２月至２０１４年８月在我眼科中心因角膜穿通伤行角膜裂伤缝合术的４６例（４６眼）患者临床资料，术后１ｄ、１周、１个月、３个月、６个月分别行裂隙灯显微镜和ＡＳ-ＯＣＴ检查，对比观察角膜穿通伤缝合术后角膜伤口的最大厚度、角膜水肿的变化、角膜伤口内口的对合及愈合情况。结果　术后１ｄＡＳ-ＯＣＴ显示角膜伤口内口裂开１５例（３２．６％），角膜伤口内口出现高低错位１７例（３６．９％），角膜伤口对合良好１１例（２３．９％），伤口内口有眼内容物附着３例（６．５％）。所有患者术后１ｄＡＳ-ＯＣＴ显示角膜伤口不同程度水肿，角膜伤口内口裂开、内口高低错位、对合良好这三种伤口形态伤口处最大角膜厚度分别为（１２２４．１±１９３．５）μｍ、（１２６７．１±１８４．３）μｍ、（１０８６．３±１１７．１）μｍ，内口错位患者角膜伤口厚度最大，内口对合良好患者角膜伤口厚度最小，术后１ｄ、１周、３个月两者之间差异均有统计学意义（均为Ｐ＜０．０５）。术后１ｄ、１周、１个月检查时，角膜伤口内口裂开、高低错位、对合良好患者角膜伤口处厚度与对侧眼对称部位角膜厚度相比差异均有统计学意义（均为Ｐ＜０．０５）。对合良好患者术后３个月时角膜伤口处厚度与对侧眼对称部位角膜厚度比较差异无统计学意义（Ｐ＞０．０５），角膜内口裂开患者术后６个月时角膜伤口处厚度与对侧眼对称部位角膜厚度比较差异无统计学意义（Ｐ＞０．０５），内口高低错位患者术后６个月时角膜伤口处厚度与对侧眼对称部位角膜厚度比较差异仍有统计学意义（Ｐ＜０．０５）。结论　ＡＳ-ＯＣＴ能清晰地观察角膜伤口的对合及愈合过程，是评价角膜裂伤缝合术后角膜伤口愈合情况的有效工具。
Abstract:
 Objective To observe the convolution and healing of corneal wound by anterior segment optical coherence tomography OCT ( AS-OCT) after corneal penetrating trauma surgery, and investigate the evaluative effects of AS-OCT in the process of corneal wound healing. Methods In this retrospective study ,46 patients (46 eyes) with corneal penetrating trauma underwent corneal suturing at Joint Shantou International Eye Center from February 2012 to August 2014 were collected. Slit-Iamp exam and AS-OCT scanrung were performed at postoperative I day, I week, I month.3 months and 6 months . and the maximum thickness of corneal wound,change of corneal edema. feature of corneal wound morphology were evaluated. Results At postoperative I day,there were 15 cases ( 32. 6% ) with corneal wound dehiscence, 17 cases ( 36. g% ) with corneal wound dislocation . 11 cases ( 23. g% ) with corneal wound proper apposition.and 3 cases(6. 5% ) with ocular contents involvement. At postoperative I day, all cases suffered different level of corneal wound edema under AS-OCT. The maximum corneal thickness for corneal wound dehiscence. dislocation. and proper apposition were ( 1224. I + 193. 5 ) Vm , ( 1267. 1 + 184. 3 ) ym , ( 1086. 3 + 117. 1) ym , respectively. At postoperative I day , I week and I month ,there were statistical differences in maximum corneal thickness between patients with corneal wound dislocation and corneal wound proper apposition ( all P < 0. 05 ) . At postoperative I day , I week and I month , there were statistical differences in comeal thickness between wounding position and contralateral eye for patients with corneal wound dehiscence , dislocation, and proper apposition ( all P < 0. 05 ) . There was no statistical difference in corneal thickness between wounding position and contralateral eye for patients with corneal wound proper apposition at postoperative 3 months (P > 0. 05 ) .no statistical difference for patients with corneal wound dehiscence at postoperative 6 months (P > 0. 05 ) .while statistical difference was found for patients with corneal wound dislocation at postoperative 6 months(P < 0. 05 ) . Conclusion It is possible to evaluate the proper apposition and healing of corneal wound using AS-OCT,which may be a prospective tool to assess the corneal wound healing after suturing.

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备注/Memo

备注/Memo:
 广东省科技厅高科技发展专项基金资助（编号：２０１２Ｂ０３１８００４８４）
更新日期/Last Update: 2015-08-31