[1]朱岩,汪军,孟忻,等. 非增殖期糖尿病视网膜病变黄斑水肿对脉络膜横断面面积的影响[J].眼科新进展,2015,35(7):683-685.[doi:10.13389/j.cnki.rao.2015.0187]
　ZHU Yan,WANG Jun,MENG Xin,et al. Effects of macular edema on choroidal cross sec on area in non-proliferative diabetic retinopathy[J].Recent Advances in Ophthalmology,2015,35(7):683-685.[doi:10.13389/j.cnki.rao.2015.0187]
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 非增殖期糖尿病视网膜病变黄斑水肿对脉络膜横断面面积的影响
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年7期
页码:
683-685
栏目:
应用研究
出版日期:
2015-07-05

文章信息/Info

Title:
 Effects of macular edema on choroidal cross sec on area in non-proliferative diabetic retinopathy
作者:
 朱岩; 汪军; 孟忻; 辛晨; 高新晓; 刘广峰; 贾宇颂; 王华
 100029　北京市，首都医科大学附属北京安贞医院眼科
Author(s):
 ZHU Yan;  WANG Jun;  MENG Xin;  XIN Chen;  GAO Xin-Xiao;  LIU Guang-Feng ; JIA Yu-Song ; WANG Hua
 Department of Ophthalmology,Beijing Anzhen HospitaL Affiliated to Capital Medical University,Beijing 100029．China
关键词:
 ; 糖尿病视网膜病变; 黄斑水肿; 脉络膜横断面面积; 光学相干断层成像
Keywords:
 ; diabetic retinopathy ;  macular edema ;  choroidal cross section area ;  optical coherence tomography
DOI:
10.13389/j.cnki.rao.2015.0187
文献标志码:
A
摘要:
 目的　通过光学相干断层成像（ｏｐｔｉｃａｌｃｏｈｅｒｅｎｃｅｔｏｍｏｇｒａｐｈｙ，ＯＣＴ）分析非增殖期糖尿病视网膜病变黄斑水肿对脉络膜横断面面积的影响。方法　收集２０１２年３月至２０１４年２月于我院眼科门诊就诊的非增殖期糖尿病视网膜病变患者４７例（５７眼），分为非增殖期糖尿病视网膜病变不伴临床显著性黄斑水肿组（ＮＰＤＲＣＳＭＥ－组）和伴临床显著性黄斑水肿组（ＮＰＤＲＣＳＭＥ＋组）。采用Ｔｏｐｃｏｎ３ＤＯＣＴ１０００脉络膜模式扫描黄斑区，比较２组之间脉络膜横断面面积差异，分析２组脉络膜横断面面积与黄斑中心凹厚度（ｃｅｎｔｒａｌｍａｃｕｌａｒｔｈｉｃｋｎｅｓｓ，ＣＭＴ）、最佳矫正视力的相关性。结果　ＮＰＤＲＣＳＭＥ－组与ＮＰＤＲＣＳＭＥ＋组性别、年龄和屈光度差异均无统计学意义（Ｐ＝０．５５０、０．７９０、０．０７０）。ＮＰＤＲＣＳＭＥ＋组脉络膜横断面面积（１１４１７５４．４７±３３７７６２．０５）μｍ２较ＮＰＤＲＣＳＭＥ－组（１３７８１２８．４５±３９５７２８．６６）μｍ２变小（Ｐ＝０．０１９）。ＮＰＤＲＣＳＭＥ－组脉络膜横断面面积与ＣＭＴ（中位数２２６．５０μｍ）之间无相关性（ｒ＝－０．１３０，Ｐ＝０．４９４）；ＮＰＤＲＣＳＭＥ＋组脉络膜横断面面积与ＣＭＴ（中位数３１７．００μｍ）之间也无相关性（ｒ＝－０．２１８，Ｐ＝０．２７４）。ＮＰＤＲＣＳＭＥ－组脉络膜横断面面积与最佳矫正最小分辨角对数视力（ＢＣｌｏｇＭＡＲ）（中位数０．０９７）之间无相关性（ｒ＝０．３２１，Ｐ＝０．０８０）；ＮＰＤＲＣＳＭＥ＋组脉络膜横断面面积与ＢＣｌｏｇＭＡＲ（中位数０．６９９）之间亦无相关性（ｒ＝－０．０７０，Ｐ＝０．７００）。结论　非增殖期糖尿病视网膜病变患者发生黄斑水肿者较未发生黄斑水肿者脉络膜横断面面积变小。脉络膜横断面面积与ＣＭＴ、最佳矫正视力均不相关。
Abstract:
 Objective To evaluate the effects of macular edema on choroidal cross section area ( CCSA) in non-proliferative diabetic retinopathy ( NPDR) by optical coherence tomography ( OCT) . Methods Forty-seven persons ( 57 eyes) with NPDR in our hospital from March 2012 to February 2014 were enrolled in this study. They were divided int0 2 groups : NPDR without clinical sigruficant macular edema ( NPDR CSME - ) group , NPDR with clinical significant macular edema ( NPDR CSME + ) group. Choroid beneath the macular was scanned with Topcon 3D OCT 1000 choroidal mode. The differences of CCSA between the two groups were analyzed. Correlation analysis was used between CCSA and central macular thickness ( CMT) . best correct visual acuity, respectively. Results The differences between NPDR CSME - group and NPDR CSME + group rn sex, age and diopter were not statistic significant (P = 0. 550 ,0. 790 . 0. 070 ) . CCSA in NPDR CSME + group was ( 1 141 754. 47 + 337 762. 05 ) Vm2 .which was thinner than CCSA in NPDR CSME - group (1 378 128. 45 + 395 728. 66) pmz (P = 0. 019) . There was no statistic significant correlation between CCSA and CMT neither in NPDR CSME - group ( median was 226. 50 ym) nor in NPDR CSME + group ( median was 317. 00 ym) ( r = - 0. 130 . - 0. 218 ;P = 0. 494 ,0. 274 ) . There was no statistic significant correlation between CCSA and best correct logarithmic nunimum angle of resolution ( BClogMAR) neither in NPDR CSME - group ( median was 0. 097) nor in NPDR CSME + group ( median was 0. 699) ( r = 0. 321 , - 0. 070 ;P = 0. 080 ,0. 700) . Conclusion Presence of macular edema in NPDR is associated with a sigruficant decrease in the CCSA. The CCSA is not related to CMT and best correct visual acuity.

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更新日期/Last Update: 2015-07-03