[1]郑彪,蔡艳霞,柯毅. 不同类型青光眼患者前部巩膜厚度与眼部生物学参数的相关性研究[J].眼科新进展,2015,35(2):177-179.[doi:10.13389/j.cnki.rao.2015.0048]
　ZHENG Biao,CAI Yan-Xia,KE Yi.Correlation between anterior sclera thickness and other ocular biological parameters in patients with different types of glaucoma[J].Recent Advances in Ophthalmology,2015,35(2):177-179.[doi:10.13389/j.cnki.rao.2015.0048]
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 不同类型青光眼患者前部巩膜厚度与眼部生物学参数的相关性研究
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
35卷
期数:
2015年2期
页码:
177-179
栏目:
应用研究
出版日期:
2015-02-05

文章信息/Info

Title:
Correlation between anterior sclera thickness and other ocular biological parameters in patients with different types of glaucoma
作者:
 郑彪; 蔡艳霞; 柯毅
 524001　广东省湛江市，广东医学院附属医院眼科
Author(s):
 ZHENG Biao;  CAI Yan-Xia ;  KE Yi
 Department of Ophthalmology,Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001, Guangdong Province.China
关键词:
 ; 青光眼; 前部巩膜厚度; 中央角膜厚度; 眼轴长度; 相关性
Keywords:
 ; glaucoma ;  anterior sclera thickness ;  central corneal thickness;  axis length ;  correlation
DOI:
10.13389/j.cnki.rao.2015.0048
文献标志码:
A
摘要:
 目的　探讨不同类型青光眼患者前部巩膜厚度（ａｎｔｅｒｉｏｒｓｃｌｅｒａｔｈｉｃｋｎｅｓｓ，ＡＳＴ）与眼部生物学参数的相关性。方法　选取２０１２年１月至２０１３年６月我院收治的青光眼患者８０例（８０眼），其中原发性闭角型青光眼（ｐｒｉｍａｒｙａｎｇｌｅ-ｃｌｏｓｕｒｅｇｌａｕｃｏｍａ，ＰＡＣＧ）３８例，原发性开角型青光眼（ｐｒｉｍａｒｙｏｐｅｎａｎｇｌｅｇｌａｕｃｏｍａ，ＰＯＡＧ）４２例，另选取于我院同期健康体检的健康无眼疾者４０例（４０眼）作为对照，采用超声生物显微镜（ｕｌｔｒａｓｏｕｎｄｂｉｏｍｉｃｒｏｓｃｏｐｙ，ＵＢＭ）对ＡＳＴ进行检测，ＤＧＨ-１０００型超声角膜测厚仪测量中央角膜厚度（ｃｅｎｔｒａｌｃｏｒｎｅａｌｔｈｉｃｋｎｅｓｓ，ＣＣＴ），同时采用眼科Ａ／Ｂ超对眼轴长度（ａｘｉａｌｌｅｎｇｔｈ，ＡＬ）进行测量，对测量结果进行比较分析。结果　ＰＯＡＧ组、ＰＡＣＧ组ＡＳＴ与对照组相比，差异均无统计学意义（均为Ｐ＞０．０５）；ＰＯＡＧ组ＡＳＴ与ＰＡＣＧ组相比，差异无统计学意义（Ｐ＞０．０５）。ＰＯＡＧ组、ＰＡＣＧ组ＣＣＴ与对照组相比，差异均有统计学意义（均为Ｐ＜０．０５），ＰＯＡＧ组、ＰＡＣＧ组ＣＣＴ均大于对照组；ＰＯＡＧ组ＣＣＴ与ＰＡＣＧ组相比，差异有统计学意义（Ｐ＜０．０５），ＰＯＡＧ组ＣＣＴ大于ＰＡＣＧ组。ＰＯＡＧ组、ＰＡＣＧ组ＡＬ与对照组相比，差异均有统计学意义（均为Ｐ＜０．０５），ＰＯＡＧ组、ＰＡＣＧ组ＡＬ均小于对照组；ＰＯＡＧ组ＡＬ与ＰＡＣＧ组相比，差异有统计学意义（Ｐ＞０．０５），ＰＯＡＧ组ＡＬ小于ＰＡＣＧ组。ＰＯＡＧ组ＣＣＴ值与ＡＳＴ值间呈线性正相关（ｒ＝０．５４４，Ｐ＝０．０１８），但ＰＡＣＧ组ＣＣＴ值与ＡＳＴ值间均未发现线性相关（ｒ＝－１２．３４５，Ｐ＝０．０５８）；两组ＡＬ与ＡＳＴ均无相关性。结论　不同类型青光眼患者的ＣＣＴ有一定的差异，但各型青光眼患者ＡＳＴ无明显差异，ＰＯＡＧ患者的ＣＣＴ与ＡＳＴ可能存在一定的正相关。
Abstract:
 Objective To discuss the correlation between anterior sclera thickness ( AST) and other ocular biological parameters in patients with different types of glaucoma. Methods Eighty patients ( 80 eyes) with different types of glaucoma in our hospital form January 2012 to June 2013 were enrolled,including 38 cases with primary angle-closure glaucoma ( PACG) and 42 cases with primary open-angle glaucoma ( POAG ) . and other 40 healthy cases (40 eyes) were chosen as controls.the AST was detected by ultrasound biomicroscopy , the central corneal thickness ( CCT) was measured by DGH-1000 corneal ultrasound pachymeter , and the axis length ( AL) was also measured by A/B ultrasound , the results were compared and analyzed. Results There was no statistical difference in AST between PACG group , POAG group and control group ( all P >0. 05 ) ,no difference was found between POAG group and PCAG group (P > 0. 05) , but there were statistical differences in CCT between PACG group, POAG group and control group ( all P < 0. 05 ) . and there was statistical difference in CCT between PACG group and POAG group ( P < 0. 05 ) . There were statistical differences in AL between PACG group , POAG group and control group ( all P < 0. 05 ) , and there was statistical difference between PACG group and POAG group (P < 0. 05 ) . In POAG group , CCT and AST value showed a linear positive correlation( r = 0. 544 ,P = 0. 018) , but in the PACG group CCT value and AST value are not linear correlation ( r = - 12. 345 ,P = 0. 058) . AL and AST of two groups had no correlation. Conclusion In patients with different types of glaucoma, CCT have some differences .but no significant difference in AST , CCT and AST in patients with POAG may be positive correlated.

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更新日期/Last Update: 2015-02-03