[1]王杰,康刚劲.端粒酶活性与白内障[J].眼科新进展,2014,34(12):1197-1200.[doi:10.13389/j.cnki.rao.2014.0333]
　WANG Jie,KANG Gang-Jin.Telomerase activity and cataract[J].Recent Advances in Ophthalmology,2014,34(12):1197-1200.[doi:10.13389/j.cnki.rao.2014.0333]
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端粒酶活性与白内障
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
34卷
期数:
2014年12期
页码:
1197-1200
栏目:
文献综述
出版日期:
2014-12-05

文章信息/Info

Title:
Telomerase activity and cataract
作者:
王杰; 康刚劲
646000　四川省泸州市，泸州医学院附属医院眼科
Author(s):
WANG Jie;  KANG Gang-Jin
Department of Ophthalmology, the Affiliated Hospital of Luzhou Medical College , Luzhou 646000 , Sichuan Province , China
关键词:
端粒酶; 端粒酶逆转录酶; 活性; 晶状体上皮细胞; 白内障
Keywords:
telomerase ;  telomerase reverse transcriptase ;  activity ;  lens epithelial cells ;  cataract
DOI:
10.13389/j.cnki.rao.2014.0333
文献标志码:
A
摘要:
端粒酶活性对人晶状体上皮细胞的增生、衰老以及白内障的发生发展具有重要作用。目前，白内障晶状体上皮细胞中端粒酶活性的改变与细胞ＤＮＡ损伤、凋亡、增殖的因果关系成为争论的焦点。本文就晶状体上皮细胞中端粒酶的表达、调节机制及其临床应用进行综述。
Abstract:
Telomerase activity plays an important role in the human lens epithelial cells ,proliferation , senescent and the occurrence and progress of cataract. At present, the causality between telomerase activity in lens epithelial cells of cataract and cell’ s DNA damage , apoptosis , proliferation become the focus of debate. This article reviews the mechanisms of the expression and regulating of telomerase activity and its clinical application in lens epithelial cells.

相似文献/References:

[1]李茂娇,康刚劲,王杰,等.雌二醇对萘处理去势雌性大鼠晶状体上皮细胞端粒酶活性与凋亡的作用[J].眼科新进展,2018,38(6):533.[doi:10.13389/j.cnki.rao.2018.0124]
　LI Mao-Jiao,KANG Gang-Jin,WANG Jie,et al.Effects of estradiol on naphthalene-induced telomerase activity and apoptosis of LEC in ovariectomized female rats[J].Recent Advances in Ophthalmology,2018,38(12):533.[doi:10.13389/j.cnki.rao.2018.0124]

更新日期/Last Update: 2014-12-04