[1]姚长海,王庆瑛,左相荣.RetCam3早产儿视网膜病变筛查中复方托吡卡胺眼液对散瞳效果及角膜厚度的影响[J].眼科新进展,2014,34(12):1151-1153.[doi:10.13389/j.cnki.rao.2014.0319]
　YAO Chang-Hai,WANG Qing-Ying,ZUO Xiang-Rong.Effects of compound tropicamide eye drops on mydriasis and corneal thickness in retinopathy of prematurity dcreening with Retcam3[J].Recent Advances in Ophthalmology,2014,34(12):1151-1153.[doi:10.13389/j.cnki.rao.2014.0319]
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RetCam3早产儿视网膜病变筛查中复方托吡卡胺眼液对散瞳效果及角膜厚度的影响
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
34卷
期数:
2014年12期
页码:
1151-1153
栏目:
应用研究
出版日期:
2014-12-05

文章信息/Info

Title:
Effects of compound tropicamide eye drops on mydriasis and corneal thickness in retinopathy of prematurity dcreening with Retcam3
作者:
姚长海; 王庆瑛; 左相荣
054000　河北省邢台市，河北医科大学附属邢台市人民医院眼科
Author(s):
YAO Chang-Hai; WANG Qing-Ying; ZUO Xiang-Rong
Department of Ophthalmology，Xingtai People’s Hospital，Heibei Medical University，Xingtai 054000， Hebei Province, China
关键词:
早产儿视网膜病变; 复方托吡卡胺眼液; 散瞳; 角膜厚度
Keywords:
retinopathy of prematurit;  compound tropicanude eye drops;  mydriasis ;  corneal thickness
DOI:
10.13389/j.cnki.rao.2014.0319
文献标志码:
A
摘要:
目的　通过复方托吡卡胺眼液对散瞳效果及角膜厚度影响的研究，为早产儿视网膜病变筛查提供更适宜的散瞳方法。方法　将进行ＲｅｔＣａｍ３早产儿视网膜病变初次筛查并需进行复查的早产儿１３１人，按不同用药方法分为Ａ、Ｂ、Ｃ、Ｄ四组，分别点入１、２、３、４次托吡卡胺眼液进行散瞳，在距最后一次散瞳１５ｍｉｎ、３０ｍｉｎ、４５ｍｉｎ时测量瞳孔直径和中央角膜厚度（ｃｅｎ-ｔｒａｌｃｏｒｎｅａｌｔｈｉｃｋｎｅｓｓ，ＣＣＴ）。结果　瞳孔散大程度组内比较：Ａ、Ｂ、Ｃ、Ｄ四组内各时间点两两比较差异均有统计学意义（均为Ｐ＜０．０５）；组间比较：散瞳１５ｍｉｎ时，Ａ组与Ｄ组、Ｂ组与Ｄ组、Ｃ组与Ｄ组差异均有统计学意义（均为Ｐ＜０．０５）；散瞳３０ｍｉｎ和４５ｍｉｎ时，Ａ组与Ｂ组、Ａ组与Ｃ组、Ａ组与Ｄ组、Ｂ组与Ｄ组、Ｃ组与Ｄ组差异均有统计学意义（均为Ｐ＜０．０５）。ＣＣＴ组内比较：Ａ、Ｂ、Ｃ、Ｄ四组内各时间点间两两比较，差异均有统计学意义（均为Ｐ＜０．０５）；组间比较：散瞳３０ｍｉｎ和４５ｍｉｎ时，Ａ组与Ｃ组、Ａ组与Ｄ组、Ｂ组与Ｃ组、Ｂ组与Ｄ组ＣＣＴ差异均有统计学意义（均为Ｐ＜０．０５）。结论　使用２次散瞳药，在距最后一次散瞳３０ｍｉｎ时进行ＲｅｔＣａｍ３早产儿视网膜病变筛查为最佳散瞳方案。
Abstract:
Objective By studying the effects of compound tropicamide eye drops on mydriasis and corneal thickness.to offer a proper way of mydriasis for retinopathy of prematurity screening. Methods A total of 131 preterm infants , who were the research objects of retinopathy of prematurity ( ROP) screerung , were divided into four groups : Group A. B . C . D according to the first screerung and the rescreening of left eye and right eye. Group A was dropped once the compound tropicamide eye drops to dilate , group B was twice , group C was 3 times , and group D was 4 times. The pupils diameter and central corneal thickness ( CCT ) were recorded at 15 nunutes . 30 minutes and 45 nunutes since the last drop of compound tropicamide eye drops. Results There was no statistical difference in the mydriatic effect at different time among group A,B,C.D ( all P > 0. 05 ) . At 15 minutes, differences were found between group A and D,group B and D,group C and D ( all P < 0. 05 ) ;At 30 minutes and 45 minutes, differences were found between group A and B , group A and C ,group A and D , group B and D,group C and D ( all P < 0. 05 ) . There were statistical differences in CCT at different time between each two groups ( all P < 0. 05 ) . At 30 nunutes and 45 nunutes .differences were found in CCT between group A and C,group A and D,group B and C,group B and D ( all P < 0.’05’) . Conclusion ’ The retinopathy of prematurity screening after dropping twice compound tropicamide eye drops and after 30 minutes since the last drop would be the most proper way of mydriasis.

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备注/Memo

备注/Memo:
河北省邢台市科技支撑计划项目（编号：２０１２ＺＣ０８７）
更新日期/Last Update: 2014-12-04