[1]李凯,王育良,张传伟,等.不同大小切口飞秒激光基质透镜切除术矫正近视术后角膜地形图对比研究[J].眼科新进展,2014,34(12):1137-1140.[doi:10.13389/j.cnki.rao.2014.0315]
　LI Kai,WANG Yu-Liang,ZHANG Chuan-Wei,et al.Effects of different incision sizes on Corne topography changes after femtosecond lenticule extraction surgery for myopia[J].Recent Advances in Ophthalmology,2014,34(12):1137-1140.[doi:10.13389/j.cnki.rao.2014.0315]
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不同大小切口飞秒激光基质透镜切除术矫正近视术后角膜地形图对比研究
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
34卷
期数:
2014年12期
页码:
1137-1140
栏目:
应用研究
出版日期:
2014-12-05

文章信息/Info

Title:
Effects of different incision sizes on Corne topography changes after femtosecond lenticule extraction surgery for myopia
作者:
李凯; 王育良; 张传伟; 吴静; 黄海燕
210029　江苏省南京市，南京中医药大学附属医院眼科
Author(s):
LI Kai;  WANG Yu-Liang ; ZHANG Chuan-Wei ;  WU Jing ;  HUANG Hai-Yan
Department of Ophthalmology,the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu Province, China
关键词:
飞秒激光; 基质透镜切除术; 近视; 角膜; 角膜地形图
Keywords:
femtosecond laser ;  lenticule extraction ;  myopia ;  cornea ;  corneal topography
DOI:
10.13389/j.cnki.rao.2014.0315
文献标志码:
A
摘要:
目的　探讨飞秒激光基质透镜切除术中采用不同大小切口对术后角膜地形图参数变化的影响。方法　将８０例（１６０眼）行飞秒激光基质透镜切除术的近视患者按切口大小分为３组，Ａ组（切口弧长１９．０ｍｍ）５０眼，Ｂ组（切口弧长５．０ｍｍ）５０眼，Ｃ组（切口弧长２．５ｍｍ）６０眼。术后随访６个月，记录术前最佳矫正视力、术后裸眼视力、裂隙灯显微镜及Ｏｒｂｓｃａｎ-Ⅱ检查模拟角膜镜读数（ＳｉｍＫ值）、后表面Ｄｉｆｆ值、３ｍｍＩｒｒｅｇ值、５ｍｍＩｒｒｅｇ值，并对结果进行分析。结果　术后１周、１个月、３个月、６个月裸眼视力３组相比，差异均无统计学意义（均为Ｐ＞０．０５）。术后６个月３组ＳｉｍＫ差值均较术前减少，差异均有统计学意义（均为Ｐ＜０．０５），但术后３组间ＳｉｍＫ差值相比较，差异无统计学意义（Ｐ＞０．０５）。术后６个月３组角膜３ｍｍＩｒｒｅｇ值、５ｍｍＩｒｒｅｇ值均较术前显著增加，差异均有统计学意义（均为Ｐ＜０．０５）；术后６个月３ｍｍＩｒｒｅｇ值、５ｍｍＩｒｒｅｇ值Ｃ组＜Ｂ组＜Ａ组，但仅５ｍｍＩｒｒｅｇ值Ｃ组与Ａ组相比差异有统计学意义（Ｐ＝０．０２４）。３组术后后表面Ｄｉｆｆ值与术前相比均显著增加（均为Ｐ＜０．０５），术后６个月后表面Ｄｉｆｆ值增加量（后表面前凸）Ｃ组＜Ｂ组＜Ａ组，但差异无统计学意义（Ｐ＞０．０５）。结论　微小切口的飞秒激光基质透镜切除术在术后角膜散光、角膜规则性和角膜后表面前凸方面都显示出较好的效果。
Abstract:
Objective To evaluate the effects of different incision sizes on the changes of corneal topography after femtosecond laser lenticule extraction for myopia. Methods A total of 80 patients ( 160 eyes) underwent femtosecond laser lenticule extraction were divided into three groups according to incision sizes: Group A ( incision size 19. 0 mm ,50 eyes) , group B ( incision size 5. 0 mm ,50 eyes) , group C ( incision size 2. 5 mm,60 eyes) . The best corrected visual acuity ( BCVA) . uncorrected visual acuity ( UCVA) , diopter , intraocular pressure and corneal topography were performed before operation and I day , I week , I month , 3 months . and 6 months after operation. Simulated keratoscopy reading ( SimK) , difference quantity ( Diff) ,3 mm irregular quantity ( Irreg) and 5 mm Irreg were recorded and analyzed. Results Compared with before operation.UCVA of three groups had no sigruficantly difference at postoperative I week, I month.3 months and 6 months ( all P > 0. 05 ) . In all patients . SimK difference value decreased significantly after the operation ( all P < 0. 05 ) , but that of three groups showed no sigruficant difference (P > 0. 05 ) . The postoperative 3 mm Irreg and 5 mm Irreg of each group were sigruficantly higher than before operation( all P < 0. 05 ) . After 6 months of operation, 3 mm Irreg and 5 mm Irreg of group C were lower than those in group A and group B.but the difference only in 5 mm Irreg between group C and A had statistical significant(P = 0. 024) . Postoperative posterior corneal surface Diff value of each group were much higher than preoperative ones ( all P < 0. 05 ) . At postoperative 6 months ,posterior corneal surface Diff value increased amount of group C and B were lower than those of group A,but the difference was not statistically significant ( P > 0. 05 ) . Conclusion Small incision lenticule extraction show good effects in postoperative corneal astigmatism, corneal regularity and posterior corneal surface ectasia.

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更新日期/Last Update: 2014-12-04