[1]何小寒,吴松一,张国明,等.玻璃体手术治疗眼内晚期视网膜母细胞瘤临床研究[J].眼科新进展,2014,34(8):764-765.[doi:10.13389/j.cnki.rao.2014.0210]
　HE Xiao-Han,WU Song-Yi,ZHANG Guo-Ming,et al.Vitreous surgery for advanced intraocular retinoblastoma[J].Recent Advances in Ophthalmology,2014,34(8):764-765.[doi:10.13389/j.cnki.rao.2014.0210]
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玻璃体手术治疗眼内晚期视网膜母细胞瘤临床研究
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
34卷
期数:
2014年8期
页码:
764-765
栏目:
应用研究
出版日期:
2014-08-05

文章信息/Info

Title:
Vitreous surgery for advanced intraocular retinoblastoma
作者:
何小寒; 吴松一; 张国明; 唐松; 宋湘梅; 田汝银; 赵军阳
广东省深圳市，深圳华侨城医院眼科
Author(s):
HE Xiao-Han; WU Song-Yi; ZHANG Guo-Ming; TANG Song; SONG Xiang-Mei; TIAN Ru-Yin; ZHAO Jun-Yang
关键词:
视网膜母细胞瘤; 玻璃体手术; 激光光凝
Keywords:
retinoblastoma ;  vitreous surgery ;  laser photocoagulation
DOI:
10.13389/j.cnki.rao.2014.0210
文献标志码:
A
摘要:
目的　探讨玻璃体手术治疗眼内晚期视网膜母细胞瘤的效果。方法　２０１２年７月至２０１３年６月，选择眼内晚期（Ｄ期或Ｅ期）视网膜母细胞瘤患儿１１例（１２眼），采用博士伦２３Ｇ玻璃体切割系统，进行玻璃体视网膜手术，包括玻璃体切割、肿瘤切除、视网膜光凝、眼内填充等。手术后随访６～１８个月（平均９．４个月）。结果　所有患眼均完成视网膜肿物切除。术后１０眼视网膜裂孔封闭、视网膜复位；２眼因肿瘤范围大，视网膜大部分切除。８眼硅油填充，２眼行Ｃ３Ｆ８填充，２眼未作眼内填充。随访末，病情稳定者８眼，肿瘤复发４眼，眼球摘除１眼，因肿瘤眼外转移去世１例，２眼再行玻璃体内注射马法兰。硅油取出３眼，硅油置换１眼，４眼硅油长期填充。视力保持０．２以上５眼，患儿因年龄小不配合视力检查者７眼。并发白内障２眼，行白内障摘出术。结论　玻璃体手术能够有效切除眼内晚期视网膜母细胞瘤，对保留眼球和患眼视力，提高患儿生存率有一定帮助，但其安全性和长期疗效还有待进一步研究。
Abstract:
Objective To investigate the effects of vitreous surgery for advanced intraocular retinoblastoma. Methods From July 2012 to June 2013 , 11 cases ( 12 eyes) with advanced intraocular retinoblastoma ( stage D or E) were collected. Vitreoretinal operation was performed using the Bausch & Lomb 23G vitrectomy system, including vitrectomy ,retinal tumor resection , photocoagulation and intraocular tamponade. After operation the follow-up time ranged from 6 months t0 18 months ( averaged 9. 4 months ) . Results Retinal tumor resection was completed in all patients. Retinal holes were closed and retina reattached inlo eyes. The tumor was too large and more retinal excisions were made in 2 eyes. There were 8 eyes with silicone oil tamponade,2 eyes with C3F8 tamponade and 2 eyes with no tamponade. At the end of follow-up , the disease was stable in 7 eyes , tumor recurred in 4 eyes , I eye underwent enucleation and I case died from tumor extraocular metastasis. Three eyes underwent silicone oil removal,l eyes underwent silicone oil replacement. Visual acuity remained above 0. 2 in 5 eyes ,7 cases were too young to be able to check visual acuity. Complicated cataract occurred in 2 eyes , the cataract extractions were performed. Conclusion Vitreous operation can effectively remove advanced intraocular retinoblastoma.retain the eyeball and visual acuities . and help to improve the survival rate ,but its safety and long-term efficacy need to further study.

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备注/Memo

备注/Memo:
深圳市卫人委项目（编号：２０１３０２１３３）
更新日期/Last Update: 2014-07-30