[1]甘露,王季芳,赵武校.角膜塑形镜偏位对近视眼视网膜周边离焦量的影响[J].眼科新进展,2024,44(4):287-290.[doi:10.13389/j.cnki.rao.2024.0056]
　GAN Lu,WANG Jifang,ZHAO Wuxiao.Influence of orthokeratology lens decentration on periretinal defocus in myopic eyes[J].Recent Advances in Ophthalmology,2024,44(4):287-290.[doi:10.13389/j.cnki.rao.2024.0056]
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
44卷
期数:
2024年4期
页码:
287-290
栏目:
应用研究
出版日期:
2024-04-05

文章信息/Info

Title:
Influence of orthokeratology lens decentration on periretinal defocus in myopic eyes
作者:
甘露; 王季芳; 赵武校
530021　广西壮族自治区南宁市，广西医学科学院，广西视光中心，广西壮族自治区人民医院视光科（甘露，赵武校）；200031　上海市，复旦大学附属眼耳鼻喉科医院（王季芳）
Author(s):
GAN Lu1; WANG Jifang2; ZHAO Wuxiao1
1.Center for Optometry and Visual Science,Guangxi Academy of Medical Sciences,the People’s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,Guangxi Zhuang Autonomous Region,China
2.Eye Institute and Department of Ophthalmology,Eye and ENT Hospital,Fudan University,Shanghai 200031,China
关键词:
近视; 角膜塑形镜; 偏位; 周边离焦
Keywords:
myopia;  orthokeratology lens;  decentration;  peripheral defocus
分类号:
R778.2
DOI:
10.13389/j.cnki.rao.2024.0056
文献标志码:
A
摘要:
目的　探讨角膜塑形镜（OK镜）偏位对近视眼视网膜周边离焦量的影响。
方法　临床对照研究。选择性收集持续配戴OK镜≥1个月的近视患者154例（234眼），根据角膜地形图离焦环位置将其分为正位组（118眼）和偏位组（116眼）。运用多光谱屈光地形图采集每位患者的视网膜周边离焦量数据，包括全视场角内的离焦值，15°、30°、45°视场角内的离焦值，上方、下方、颞侧、鼻侧眼底区域的离焦值等。采用独立样本t检验比较两组患者间各指标的差异，多因素相关分析（广义估计方程）用于分析组内临床参数与视网膜周边离焦量的关系。
结果　偏位组患者鼻侧视网膜周边离焦量显著低于正位组（t=2.668，P=0.008），其余参数间差异均无统计学意义（均为P>0.05)。广义估计方程显示，年龄是上方视网膜周边离焦量的影响因素，二者呈正相关；角膜陡K是下方视网膜周边离焦量的影响因素，二者呈负相关；性别是颞侧视网膜周边离焦量的影响因素，女性OK镜配戴者所产生的颞侧视网膜周边离焦量更小；鼻侧视网膜周边离焦量的影响因素包含镜片是否偏位、眼别及患者年龄，其中鼻侧视网膜周边离焦量与年龄呈正相关，左眼鼻侧视网膜周边离焦量明显优于右眼。
结论　OK镜亚临床水平的偏位可能使近视患者获得较好的鼻侧视网膜周边离焦量；近视患者视网膜周边离焦量受OK镜配戴者年龄、性别、角膜陡K、镜片偏位量及眼别等多因素影响。
Abstract:
Objective　To investigate the effect of orthokeratology (OK) lens decentration on peripheral retinal defocus in myopic eyes.
Methods　Totally 154 patients (234 eyes) continuously wearing OK lenses for one month or more were recruited in this study. According to the location of defocus rings in corneal topography, these eyes were divided into the centration group (118 eyes) and the decentration group (116 eyes). Peripheral retinal defocus data of each patient was collected by multispectral refraction topography, including total refraction difference value (TRDV), refraction difference value at 15° (RDV-15), refraction difference value at 30° (RDV-30), refraction difference value at 45° (RDV-45), superior refraction difference value (RDV-S), inferior refraction difference value (RDV-I), temporal refraction difference value (RDV-T) and nasal refraction difference value (RDV-N). An independent sample t-test was used to compare the differences in these parameters between the two groups, and multivariate correlation analysis (generalized estimating equation, GEE) was conducted to analyze the relationship between clinical parameters and the amount of peripheral retinal defocus within the group.
Results　The RDV-N of patients in the decentration group was significantly lower than that in the centration group (t=2.668, P=0.008), and there were no significant differences in other parameters (all P>0.05). GEE showed that age was the determinant of RDV-S, and they were positively correlated; steep K was the determinant of RDV-I, and they were negatively correlated; gender was the determinant of RDV-T, and female OK lens wearers showed less RDV-T; the determinants of RDV-N include the alignment of OK lens, eye distribution and age, among which, RDV-N was positively corrected with age, and RDV-N of the left eyes was significantly superior to that of the right eyes.
Conclusion　Subclinical decentration of the OK lens may result in better RDV-N of myopia patients. The peripheral retinal defocus is influenced by factors such as age, gender, steep K, amount of decentration and eye distribution of OK lens wearers.

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备注/Memo

备注/Memo:
国家自然科学基金项目（编号：82360214）；广西自然科学基金项目（编号：2023GXNSFAA026114）
更新日期/Last Update: 2024-04-05