[1]赖伟霞,贾亦悦,张雨艺,等.低强度红光在低龄高度近视儿童中的疗效研究[J].眼科新进展,2022,42(9):727-730.[doi:10.13389/j.cnki.rao.2022.0149]
　LAI Weixia,JIA Yiyue,ZHANG Yuyi,et al.Efficacy of low-level red light in young children with high myopia[J].Recent Advances in Ophthalmology,2022,42(9):727-730.[doi:10.13389/j.cnki.rao.2022.0149]
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低强度红光在低龄高度近视儿童中的疗效研究/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
42卷
期数:
2022年9期
页码:
727-730
栏目:
应用研究
出版日期:
2022-09-05

文章信息/Info

Title:
Efficacy of low-level red light in young children with high myopia
作者:
赖伟霞; 贾亦悦; 张雨艺; 黎海平; 吴西西
530023　广西壮族自治区南宁市，广西中医药大学第一附属医院眼科
Author(s):
LAI Weixia; JIA Yiyue; ZHANG Yuyi; LI Haiping; WU Xixi
Department of Ophthalmology,the First Affiliated Hospital of Guangxi Traditional Chinese Medical University,Nanning 530023,Guangxi Zhuang Autonomous Region,China
关键词:
低强度红光; 低龄高度近视; 眼轴长度; 等效球镜
Keywords:
low-level red light;  high myopia at a young age;  axis length;  spherical equivalent
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2022.0149
文献标志码:
A
摘要:
目的　评估低强度红光（LLRL）在低龄高度近视儿童中的疗效。方法　招募年龄≤10岁的高度近视儿童50例，最终40例（右眼）纳入研究。根据LLRL、足矫单光眼镜（SVS）干预及弱视情况分为LLRL弱视组（15例）、LLRL非弱视组（11例）、SVS弱视组（9例）、SVS非弱视组（5例）。干预前（基线）以及干预后（1个月、3个月、6个月），分别对入组儿童进行最佳矫正视力（BCVA）、等效球镜（SER）、眼轴长度（AL）、SER增长量、AL增长量检测。分别比较两弱视组间、两非弱视组间各时间点检测指标的差异。结果　两弱视组间和两非弱视组间患者的性别、年龄、基线BCVA、基线SER、基线AL差异均无统计学意义（均为P>0.05）。LLRL弱视组患者BCVA在干预后1个月、3个月、6个月均大于SVS弱视组，SER增长量在干预后3个月、6个月均高于SVS弱视组，AL增长量在干预后1个月、3个月、6个月均低于SVS弱视组（均为P<0.05），而两弱视组患者间干预后1个月、3个月、6个月SER、AL以及干预后1个月SER增长量差异均无统计学意义（均为P>0.05）。LLRL非弱视组患者SER增长量在干预后1个月、3个月、6个月均大于SVS非弱视组（均为P<0.05），AL增长量在干预后1个月、3个月、6个月均低于SVS非弱视组（均为P<0.05），而干预后1个月、3个月、6个月两弱视组患者间BCVA、SER、AL差异均无统计学意义（均为P>0.05）。结论　LLRL在低龄高度近视儿童中有一定短期疗效，既能治疗弱视的同时也能很好防控近视，可作为低龄高度近视儿童治疗的一个优质选择。
Abstract:
Objective　To evaluate the efficacy of low-level red light (LLRL) in young children with high myopia. Methods　Fifty children with high myopia under the age of 10 were recruited, and 40 (right eyes) were finally included in the study. According to LLRL, single vision spectacles (SVS) intervention and amblyopia, they were divided into the LLRL amblyopic group (15 patients), LLRL non-amblyopic group (11 patients), SVS amblyopic group (9 patients), and SVS non-amblyopic group (5 patients). Before the intervention (baseline) and after the intervention (1 month, 3 months, 6 months), the best corrected visual acuity (BCVA), spherical equivalent refraction (SER), axial length (AL), SER growth, and AL growth were measured, respectively. The differences in said indicators at each time point were compared between the two amblyopic groups and the two non-amblyopic groups. Results　There were no statistically significant differences in gender, age, baseline BCVA, baseline SER, and baseline AL between the two amblyopic groups and the two non-amblyopic groups (all P>0.05).Compared with the SVS amblyopic group, BCVA at 1 month, 3 months and 6 months after the intervention in the LLRL amblyopic group was higher, SER growth at 3 months and 6 months after the intervention was higher, and AL growth at 1 month, 3 months and 6 months after the intervention was lower (all P<0.05), while there were no significant differences in SER and AL at 1 month, 3 months and 6 months after the intervention and SER growth at 1 month after the intervention between the two amblyopic groups (all P>0.05).Compared with the SVS non-amblyopic group, SER growth at 1 month, 3 months and 6 months after the intervention in the LLRL non-amblyopic group was higher (all P<0.05), and AL growth at 1 month, 3 months and 6 months after the intervention was lower (all P<0.05), while there were no significant differences in BCVA, SER and AL between the two non-amblyopic groups at 1 month, 3 months and 6 months after the intervention (all P>0.05). Conclusion　LLRL has a short-term effect in young children with high myopia, which can treat amblyopia and prevent myopia. So, it can be used as a high-quality treatment option for young children with high myopia.

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备注/Memo

备注/Memo:
广西科技厅资助项目（编号：桂科AB18126034，桂科AB20238029）;广西中医药大学第一附属医院青年科学基金（编号：GZYQJ24）
更新日期/Last Update: 2022-09-05