[1]李映昱,袁翌斐,张钰,等.硅水凝胶角膜接触镜senofilcon A和comfilcon A在LASEK术后应用的对比研究[J].眼科新进展,2022,42(3):226-229.[doi:10.13389/j.cnki.rao.2022.0046]
　LI Yingyu,YUAN Yifei,ZHANG Yu,et al.Comparison of clinical effects of senofilcon A and comfilcon A silicone hydrogel contact lenses after laser-assisted subepithelial keratectomy[J].Recent Advances in Ophthalmology,2022,42(3):226-229.[doi:10.13389/j.cnki.rao.2022.0046]
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硅水凝胶角膜接触镜senofilcon A和comfilcon A在LASEK术后应用的对比研究/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
42卷
期数:
2022年3期
页码:
226-229
栏目:
应用研究
出版日期:
2022-03-05

文章信息/Info

Title:
Comparison of clinical effects of senofilcon A and comfilcon A silicone hydrogel contact lenses after laser-assisted subepithelial keratectomy
作者:
李映昱; 袁翌斐; 张钰; 刘嫣; 陈跃国
100191　北京市，北京大学第三医院眼科
Author(s):
LI Yingyu; YUAN Yifei; ZHANG Yu; LIU Yan; CHEN Yueguo
Department of Ophthalmology,Peking University Third Hospital,Beijing 100191，China
关键词:
角膜接触镜; 硅水凝胶; LASEK
Keywords:
corneal contact lens;  silicone hydrogel;  laser-assisted subepithelial keratectomy
分类号:
R779.6
DOI:
10.13389/j.cnki.rao.2022.0046
文献标志码:
A
摘要:
目的　对比硅水凝胶角膜接触镜senofilcon A和comfilcon A在准分子激光上皮下角膜磨镶术（LASEK）术后应用的临床效果。方法　采用前瞻性随机双盲自身对照试验的方法，纳入行LASEK患者39例（78眼），术后同一患者一眼配戴senofilcon A角膜接触镜（A组），另一眼配戴comfilcon A角膜接触镜（B组），连续配戴7 d。评估并比较两组患眼术后主观感受和客观体征的差别。结果　手术当天，B组患眼的眼痛评分为（2.03±2.03）分，高于A组［（1.49±1.68）分］（P=0.024）。术后1 d，B组患眼的眼痛、流泪、异物感评分均高于A组（P眼痛=0.001，P流泪=0.032，P异物感=0.025）；术后3 d、7 d，两组患眼间的主观感受评分差异均无统计学意义（均为P>0.05)。在术后视力、角膜上皮愈合、角膜上皮水肿、结膜充血等客观体征方面，两组患眼在观察期内差异均无统计学意义（均为P>0.05)。结论　硅水凝胶角膜接触镜senofilcon A和comfilcon A在LASEK术后促进角膜上皮再生方面没有明显差别，但senofilcon A在术后早期患者舒适度方面较comfilcon A更有优势。
Abstract:
Objective　To evaluate and compare the clinical effect of senofilcon A and comfilcon A silicone hydrogel contact lenses following the laser-assisted subepithelial keratectomy (LASEK).Methods　A prospective, randomized, double-blind, self-control trial was conducted in 39 patients (78 eyes) who underwent LASEK. After the operation, one eye wore senofilcon A lens (group A) and the fellow eye wore comfilcon A lens (group B) for 7 consecutive days. The subjective feelings and objective signs between the two groups were evaluated and compared.Results　On the day of surgery, the pain score of eyes in group B was 2.03±2.03, higher than that in group A (1.49±1.68) (P=0.024). On the first day after surgery, the scores for eye pain, lacrimation and foreign body sensation in group B were higher than those in group A (Peye pain=0.001, Placrimation=0.032, Pforeign body sensation=0.025). On the third and seventh days after surgery, there was no significant difference in subjective feelings between the two groups (all P>0.05). During the observation period, there was no significant difference between the two groups in objective signs, such as visual acuity, corneal epithelial healing, corneal epithelial edema, and conjunctival congestion (all P>0.05).Conclusion　Senofilcon A and comfilcon A silicone hydrogel contact lenses have no significant difference in promoting corneal epithelial regeneration after LASEK. However, senofilcon A lenses are more comfortable than comfilcon A lenses in the early postoperative period.

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更新日期/Last Update: 2022-03-05