[1]任中豪,徐丽妍,杨凯丽,等.配戴硬性透气性角膜接触镜对轻中度圆锥角膜患者视觉质量的影响[J].眼科新进展,2020,40(7):634-637.[doi:10.13389/j.cnki.rao.2020.0145]
 REN Zhonghao,XU Liyan,YANG Kaili,et al.Assessment of rigid gas-permeable contact lenses on visual quality in mild and moderate keratoconus[J].Recent Advances in Ophthalmology,2020,40(7):634-637.[doi:10.13389/j.cnki.rao.2020.0145]
点击复制

配戴硬性透气性角膜接触镜对轻中度圆锥角膜患者视觉质量的影响/HTML
分享到:

《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
40卷
期数:
2020年7期
页码:
634-637
栏目:
应用研究
出版日期:
2020-07-05

文章信息/Info

Title:
Assessment of rigid gas-permeable contact lenses on visual quality in mild and moderate keratoconus
作者:
任中豪徐丽妍杨凯丽范棋任胜卫赵东卿
450003 河南省郑州市,河南大学人民医院 河南省人民医院 河南省立眼科医院
Author(s):
REN Zhonghao XU Liyan YANG Kaili FAN Qi REN Shengwei ZHAO Dongqing
Henan University People’s Hospital, Henan Provincial People’s Hospital, Henan Eye Hospital, Zhengzhou 450003, Henan Province,China
关键词:
圆锥角膜视觉质量客观散射指数调制传递函数截止频率对比度视力
Keywords:
keratoconus visual quality objective scatter index modulation transfer function cut off frequency contrast vision
分类号:
R778
DOI:
10.13389/j.cnki.rao.2020.0145
文献标志码:
A
摘要:
目的 探讨配戴硬性透气性角膜接触镜(rigid gas-permeable contact lense,RGPCL)对轻中度圆锥角膜患者视觉质量的影响。方法 选取2018年12月至2019年6月在河南省人民医院门诊确诊为轻中度圆锥角膜的患者20例25眼。轻中度圆锥角膜的诊断标准及分期依据全球圆锥角膜专家共识及圆锥角膜评分标准。应用视觉质量分析系统II(OQAS-II)检查患者在配戴RGPCL前及配戴1个月后各视觉质量参数,包括客观散射指数(objective scatter index,OSI)、调制传递函数截止频率(modulation transfer function cut off frequency,MTFcut off)、斯特列尔比(strehl ratio,SR),三种模拟对比度下视力OV100%、OV20%、OV9%及19.5 s内不瞬目情况下泪膜散射指数(tear film objective scatter index,TF-OSI)。同时分析各视觉质量参数与角膜前表面中央3 mm光学区Ksteep的相关性。结果 配戴RGPCL前与配戴1个月后相比,OSI明显降低,MTFcut off、SR、OV100%、OV20%、OV9%均明显升高,差异均有统计学意义(均为P<0.05)。配戴RGPCL前与配戴1个月后相比,TF-OSI差异无统计学意义(P>0.05)。配戴RGPCL前,OSI及TF-OSI与Ksteep呈正相关,MTFcut off、SR、OV100%、OV20%、OV9%与Ksteep均呈负相关(均为P<0.05);配戴RGPCL 1个月后,除TF-OSI与Ksteep呈正相关(P<0.05)外,OSI、MTFcut off、SR、OV100%、OV20%、OV9%与Ksteep均无相关性(均为P>0.05)。结论 RGPCL可明显提高轻中度圆锥角膜患者的视觉质量。
Abstract:
Objective To evaluate the influence of rigid gas-permeable contact lens (RGPCL) on visual quality in patients with mild and moderate keratoconus. Methods Twenty-five eyes of twenty mild and moderate keratoconus patients were recruited in Henan Provincial People’s Hospital from December 2018 to June 2019. The diagnosis and staging of mild and moderate keratoconus were based on Global Consensus on Keratoconus and Keratoconus Severity Score Ranking Scheme (KSS). The patients were analyzed by optical quality analysis system II (OQAS-II) before and one month after wearing RGPCL respectively, including the value of objective scattering index (OSI), modulation transfer function cut off frequency (MTFcut off), strehl ratio (SR), OQAS values under different contrast(OV100%, OV20% and OV9%), and tear film objective scatter index (TF-OSI) without blinking for 19.5 seconds. Person product moment coefficient was used to evaluate the correlation between the optical quality parameters and Ksteep. Results The OSI decreased significantly and the MTFcut off, SR, OV100%, OV20% and OV9% increased significantly one month after wearing RGPCL, and there were statistically significant difference compared to the pre-treatment (all P<0.05). The TF-OSI showed no statistical difference one month after wearing RGPCL compared to the pre-treatment (P>0.05). The OSI and TF-OSI were positively correlated with Ksteep, and the MTFcut off, SR, OV100%, OV20% and OV9% were negatively correlated with Ksteep before wearing RGPCL (all P<0.05).The OSI, MTFcut off, SR, OV100%, OV20% and OV9% showed no significant correlation with Ksteep one month after wearing RGPCL (all P<0.05) except the TF-OSI was positively correlated with Ksteep (P>0.05). Conclusion RGPCL can significantly improve the visual quality in patients with mild and moderate keratoconus.

参考文献/References:

[1] RABINOWITZ Y S.Keratoconus [J].Surv Ophthalmol,1998,42(4):297-319.
[2] KYMES S M,WALLINE J J,ZADNIK K,STERLING J,GORDON M O.Changes in the quality-of-life of people with keratoconus [J].Am J Ophthalmol,2008,145(4):611-617.
[3] MILLODOT M,SHNEOR E,ALBOU S,ATLANI E,GORDON-SHAAG A.Prevalence and associated factors of keratoconus in Jerusalem: A cross-sectional study [J].Ophthalmic Epidemiol,2011,18(2):91-97.
[4] MCGHEE C N,KIM B Z,WILSON P J.Contemporary treatment paradigms in keratoconus [J].Cornea,2015,34(Suppl 10):16-23.
[5] DOWNIE L E,LINDSAY R G.Contact lens management of keratoconus [J].Clin Exp Optom,2015,98(4):299-311.
[6] 谢培英,王丹,杨丽娜,周文娟.透气性硬性接触镜矫正圆锥角膜的视觉质量评价[J].中华眼科杂志,2005,41(12):1086-1091.
XIE P Y,WANG D,YANG L N,ZHOU W J.The evaluation of visual quality in keratoconus eyes corrected by rigid gas-permeable contact lens [J].Chin J Ophthalmol,2005,41(12):1086-1091.
[7] VILASECA M,ARJONA M,PUJOL J,ISSOLIO L,GUELL J L.Optical quality of foldable monofocal intraocular lenses before and after injection: comparative evaluation using a double-pass system [J].J Cataract Refract Surg,2009,35(8):1415-1423.
[8] GOMES J A,TAN D,RAPUANO C J,BELIN M W,AMBRSIO R Jr,GUELL J L,et al.Global consensus on keratoconus and ectatic diseases [J].Cornea,2015,34(4):359-369.
[9] ZADNIK K,BARR J T,GORDON M O,EDRINGTON T B.Biomicroscopic signs and disease severity in keratoconus.Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Group[J].Cornea,1996,15(2):139-146.
[10] APPLEGATE R A,MARSACK J D,RAMOS R,SARVER E J.Interaction between aberrations to improve or reduce visual performance [J].J Cataract Refract Surg,2003,29(8):1487-1495.
[11] JINABHAI A,NEIL CHARMAN W,O’DONNELL C,RADHAKRISHNAN H.Optical quality for keratoconic eyes with conventional RGP lens and simulated,customised contact lens corrections: a comparison [J].Ophthalmic Physiol Opt,2012,32(3):200-212.
[12] SPADEA L,MARAONE G,VERBOSCHI F,VINGOLO E M,TOGNETTO D.Effect of corneal light scatter on vision: a review of the literature [J].Int J Ophthalmol,2016,9(3):459-464.
[13] DíAZ-DOUTN F,BENITO A,PUJOL J,ARJONA M,GELL J L,ARTAL P.Comparison of the retinal image quality with a Hartmann-Shack wavefront sensor and a double-pass instrument [J].Invest Ophthalmol Vis Sci,2006,47(4):1710-1716.
[14] YE C,NG P K,JHANJI V.Optical quality assessment in normal and forme fruste keratoconus eyes with a double-pass system: a comparison and variability study [J].Br J Ophthalmol,2014,98(11):1478-1483.
[15] MARTNEZRODA J A,VILASECA M,ONDATEGUI J C,GINER A,BURGOS F J,CARDONA G,et al.Optical quality and intraocular scattering in a healthy young population [J].Clin Exp Optom,2011,94(2):223-229.
[16] LEONARD A P,GARDNER S D,ROCHA K M,ZELDIN E R,TREMBLAY D M,WARING G O.Double-pass retina point imaging for the evaluation of optical light scatter,retinal image quality,and staging of keratoconus [J].J Refract Surg,2016,32(11):760-765.
[17] HINDMAN H B,MCCALLY R L,MYROWITZ E,TERRY M A,STARK W J,WEINBERG R S,et al.Evaluation of deep lamellar endothelial keratoplasty surgery using scatterometry and wavefront analyses [J].Ophthalmology,2007,114(11):2006-2012.
[18] JESTER J V,MOLLER-PEDERSEN T,HUANG J,SAX C M,KAYS W T,CAVANGH H D,et al.The cellular basis of corneal transparency: evidence for ‘corneal crystallins’[J].J Cell Sci,1999,112 ( Pt 5):613-622.
[19] BITIRGEN G,OZKAGNICI A,MALIK R A,OLTULU R.Evaluation of contact lens induced changes in keratoconic corneas using in vivo confocal microscopy [J].Invest Ophthalmol Vis Sci,2013,54(8):5385-5391.
[20] JINABHAI A,RADHAKRISHNAN H,TROMANS C,O’DONNELL C.Visual performance and optical quality with soft lenses in keratoconus patients [J].Ophthalmic Physiol Opt,2012,32(2):100-116.
[21] MAEDA N,FUJIKADO T,KURODA T,MIHASHI T,HIROHARA Y,NISHIDA K,et al.Wavefront aberrations measured with Hartmann-Shack sensor in patients with keratoconus [J].Ophthalmology,2002,109(11):1996-2003.
[22] OKAMOTO C,OKAMOTO F,SAMEJIMA T,MIYATA K,OSHIKA T.Higher-order wavefront aberration and letter-contrast sensitivity in keratoconus [J].Eye,2008,22(12):1488-1492.
[23] NEGISHI K,KUMANOMIDO T,UTSUMI Y,TSUBOTA K.Effect of higher-order aberrations on visual function in keratoconic eyes with a rigid gas permeable contact lens[J].Am J Ophthalmol,2007,144(6):924-929.
[24] GORDON-SHAAG A,MILLODOT M,IFRAH R,SHNEOR E.Aberrations and topography in normal,keratoconus-suspect,and keratoconic eyes [J].Optom Vis Sci,2012,89(4):411-418.
[25] 石迎辉,王丽娅,吕天斌,覃建.配戴透气性硬性角膜接触镜后圆锥角膜眼高阶像差的变化[J].中华眼科杂志,2011,47(7):601-606.
SHI Y H,WANG L Y,LYU T B,QIN J.Changes of ocular higher order aberration in keratoconus eyes wearing rigid gas-permeable contact lens [J].Chin J Ophthalmol,2011,47(7):601-606.
[26] SHOKROLLAHZADEH F,HASHEMI H,JAFARZADEHPUR E,MIRZAJANI A,KHABAZKHOOB M,YEKTA A,et al.Corneal aberration changes after rigid gas permeable contact lens wear in keratokonic patients [J].J Curr Ophthalmol,2016,28(4):194-198.
[27] LU F,MAO X,QU J,XU D,HE J C.Monochromatic wavefront aberrations in the human eye with contact lenses [J].Optom Vis Sci,2003,80(2):135-141.
[28] 高彦,林潇,刘明娜,王海莹,陈百秋,史伟云,等.硬性透气性角膜接触镜矫正圆锥角膜不规则散光后对比度视力的观察[J].眼科,2010,19(3):183-186.
GAO Y,LIN X,LIU M N,WANG H Y,CHEN B Q,SHI W Y,et al.Clinical observation of contrast visual acuity after correcting irregular astigmatism for keratoconus by rigid gas-permeable lenses [J].Ophthalmol CHN,2010,19(3):183-186.
[29] JINABHAI A,O’DONNELL C,RADHAKRISHNAN H.Changes in refraction,ocular aberrations,and corneal structure after suspending rigid gas-permeable contact lens wear in keratoconus[J].Cornea,2012,31(5):500-508.
[30] CARRACEDO G,GONZLEZ-MIJOME J M,MARTN-GIL A,CARBALLO J,PINTOR J.The influence of rigid gas permeable lens wear on the concentrations of dinucleotides in tears and the effect on dry eye signs and symptoms in keratoconus [J].Cont Lens Anterior Eye,2016,39(5):375-379.

相似文献/References:

[1]王向华 赵宏 丁相奇.两种深板层角膜移植术治疗圆锥角膜的比较研究[J].眼科新进展,2012,32(4):000.
[2]刘彩娟 谭少健 李霞 唐东永 黄宝宇 梁皓.有晶状体眼虹膜固定型人工晶状体植入术后远期视觉质量[J].眼科新进展,2012,32(11):000.
[3]吴东芳 张小兰 邱乐梅 王顺清 孙成淑 邓应平.圆锥角膜的诊断与治疗[J].眼科新进展,2012,32(12):000.
[4]罗畅 邓应平.性别及年龄对圆锥角膜发病与进展的影响[J].眼科新进展,2013,33(2):000.
[5]王凌飞 杨瑞波 赵少贞.CACHET有晶状体眼人工晶状体植入术后视觉质量的临床评价[J].眼科新进展,2013,33(6):000.
[6]蔡啸谷 乔利亚 张烨 谭家璿 管征 万修华 王宁利.双通道视觉质量分析系统可靠性评价及相关影响因素分析[J].眼科新进展,2013,33(7):000.
[7]范罕英 张玙 杜之渝.飞秒激光与机械刀制瓣LASIK术后视觉质量的研究进展[J].眼科新进展,2013,33(7):000.
[8]李兆春 倪海龙 吴静辉 王丽娟 宋峰伟.不同折射率和镀膜工艺光学镜片对近视眼视觉质量的影响[J].眼科新进展,2013,33(9):000.
[9]韩莎莎 王婷 孟丽丽 史伟云.深板层及穿透性角膜移植术治疗圆锥角膜术后屈光状态的比较[J].眼科新进展,2013,33(9):000.
[10]韦伟 杨晓钊 张长宁 朱秀萍.Comfort-Kone硬性角膜接触镜矫治圆锥角膜的临床观察[J].眼科新进展,2012,32(1):000.

备注/Memo

备注/Memo:
河南省基础与前沿技术研究计划项目(编号:162300410235);河南省自然科学基金项目(编号:182300410362)
更新日期/Last Update: 2020-07-05