[1]何吕福,王晓华,湛丽莎,等.带中心孔植入式透镜（V4c-ICL）矫正高度近视的视觉质量研究[J].眼科新进展,2019,39(9):866-869.[doi:10.13389/j.cnki.rao.2019.0197]
　HE Lü-Fu,WANG Xiao-Hua,ZHAN Li-Sha,et al.Quality of vision after implantation of implantable collamer lens with a central hole (V4c-ICL) for high myopia[J].Recent Advances in Ophthalmology,2019,39(9):866-869.[doi:10.13389/j.cnki.rao.2019.0197]
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带中心孔植入式透镜（V4c-ICL）矫正高度近视的视觉质量研究/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年9期
页码:
866-869
栏目:
应用研究
出版日期:
2019-09-05

文章信息/Info

Title:
Quality of vision after implantation of implantable collamer lens with a central hole (V4c-ICL) for high myopia
作者:
何吕福; 王晓华; 湛丽莎; 张新
621000　四川省绵阳市，绵阳市第三人民医院，四川省精神卫生中心
Author(s):
HE Lü-Fu; WANG Xiao-Hua; ZHAN Li-Sha; ZHANG Xin
Third Hospital of Mianyang，Sichuan Mental Health Center，Mianyang 621000，Sichuan Province，China
关键词:
高度近视; V4c-ICL; 临床效果; 视觉质量
Keywords:
high myopia; V4c-ICL; clinical effect; quality of vision
分类号:
R778.1
DOI:
10.13389/j.cnki.rao.2019.0197
文献标志码:
A
摘要:
目的　观察高度近视患者植入带中心孔植入式透镜（implantable collamer lens，ICL）后的临床疗效和视觉相关的生活质量。方法　前瞻性病例研究。选取我院诊断为高度近视，并植入V4c-ICL患者25例（50眼）为研究对象。术前及术后1个月、3个月、6个月分别检查患者屈光状态，裸眼远、中、近视力，最佳矫正远视力，远视力矫正下中、近视力，双眼视力，眼压，角膜内皮细胞密度（corneal endothelial cell density，ECD），并进行国家眼科研究所视功能问卷-25（national eye institute-visual function questionnaire，NEI-VFQ-25）调查及评分。结果　高度近视患者植入V4c-ICL后不同时间球镜、柱镜、等效球镜（spherical equivalent，SE）度较术前均明显降低（F=884.35、17.15、810.25，均为P＜0.05）；术后不同时间裸眼远、中、近视力，最佳矫正远视力，远视力矫正下中、近视力和双眼视力较术前均明显改善（F=604.47、878.13、713.92、22.25、5.33、6.90、16.51，均为P＜0.05）。术前及术后随访期间眼压、ECD无明显变化（F=0.07、1.53，均为P＞0.05）；术后NEI-VFQ-25评分较术前明显提高（F=21.76，P＜0.05）。结论　高度近视患者植入V4c-ICL后屈光不正得到矫正、短期内屈光稳定，随访期间远、中、近视力明显提高，视觉相关的生活质量明显改善。V4c-ICL植入术治疗高度近视安全、有效。
Abstract:
Objective　To observe the clinical effect and vision related quality of life after implantation of V4c-ICL for high myopia.Methods　Prospective case study.We observed 25 high myopia patients (50 eyes) with V4c-ICL as the research objects.Patients’ refractive status,the uncorrected distant vision acuity (UDVA),uncorrected intermediate vision acuity (UIVA) and uncorrected near vision acuity (UNVA),the best corrected distant vision acuities (CDVA),distance-corrected intermediate visual acuity and distance-corrected near visual acuity (DCNVA),binocular visual acuities(BVA),intraocular pressure,corneal endothelial cell density (ECD) were examined preoperatively and one month,three months and six months after the implantation respectively,and the national eye institute-visual function questionnaire-25(NEI-VFQ-25) was conducted and evaluated.Results　Diopter (D) of sphere power,cylinder power and spherical equivalent (SE) after implantation of V4c-ICL for high myopia were decreased significantly during the follow-up period(F=884.35,17.15,810.25,respectively;all P<0.05).UDVA,UIVA,UNVA,CDVA,DCIVA,DCNVA and BVA were increased significantly after implantation of V4c-ICL(F=604.47,878.13,713.92,22.25,5.33,6.90,16.51,respectively;all P<0.05).Intraocular pressure and ECD had no obvious change before the operation and during the post-operation follow-up period (F=0.07,1.53,respectively;all P>0.05).After the implantation,scored in the NEI-VFQ-25 were remarkably higher compared with the preoperative ones,(F=21.76,P＜0.05).Conclusion　The ametropia in high myopia is corrected after implantation of V4c-ICL and the refraction remains stable in the short term.The distant,intermediate and near visual acuities during the follow-up period are obviously improved,and vision related quality of life is also obviously improved.Implantation of V4c-ICL for high myopia is safe and effective.

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更新日期/Last Update: 2019-08-26