[1]于莎莎,赵云,汤欣.视神经损伤药物治疗的研究进展[J].眼科新进展,2019,39(3):291-295.[doi:10.13389/j.cnki.rao.2019.0066]
　YU Sha-Sha,ZHAO Yun,TANG Xin.Recent advances in pharmacological therapy for the optic nerve injury[J].Recent Advances in Ophthalmology,2019,39(3):291-295.[doi:10.13389/j.cnki.rao.2019.0066]
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视神经损伤药物治疗的研究进展/HTML
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《眼科新进展》[ISSN:1003-5141/CN:41-1105/R]

卷:
39卷
期数:
2019年3期
页码:
291-295
栏目:
文献综述
出版日期:
2019-03-05

文章信息/Info

Title:
Recent advances in pharmacological therapy for the optic nerve injury
作者:
于莎莎; 赵云; 汤欣
300020　天津市，天津市眼科医院、天津市眼科学与视觉科学重点实验室、天津市眼科研究所、天津医科大学眼科临床学院
Author(s):
YU Sha-Sha; ZHAO Yun; TANG Xin
Tianjin Eye Hospital and Institute，Clinical College of Ophthalmology of Tianjin Medical，Tianjin Key Laboratory of Ophthalmology and Vision Science Tianjin 300020，China
关键词:
药物疗法; 视网膜神经节细胞; 视神经损伤
Keywords:
drug therapy; retinal ganglion cells; optic nerve injury
分类号:
R774.6
DOI:
10.13389/j.cnki.rao.2019.0066
文献标志码:
A
摘要:
视神经损伤是眼科常见的致盲性眼病，目前临床上尚无特效治疗方法。临床上常用的视神经损伤治疗方法主要有药物和手术两大类。治疗视神经损伤的药物主要有糖皮质激素、血管舒张剂、神经营养因子、钙离子通道阻滞剂、N-甲基-D-天门冬氨酸受体拮抗剂、Rho激动酶抑制剂以及抗氧化剂等。但传统激素和神经营养因子的疗效有限，为此，各国研究者仍在不断探索新的治疗药物。本文就近年来国内外视神经损伤药物治疗的研究进展进行综述。
Abstract:
Optic nerve injury is one of the leading causes of blindness，and effective treatment methods are still lacking up to now.In clinical，drug and operative therapy are the two major methods adopted for the treatment of the optic nerve injury.Drug therapy included the glucocorticoid，vasodilator，neuro-trophic factors，calcium channel blocker，N-methyl-D-aspartate receptors，Rho-kinase inhibitor and antioxidants，etc.However，the effect of the traditional glucocorticoid and neuro-trophic factors is limited，so new drugs are still under explored by experts worldwide.In this study，we reviewed the updated studies of the drug therapy for the optic nerve injury.

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更新日期/Last Update: 2019-03-15